Wednesday, March 12, 2025

 CIVILIZATION HO!

Marine litter has already reached the deepest point in the Mediterranean Sea



The bottom of the Calypso Deep, a 5,112-metre deep depression in the Ionian Sea, contains one of the highest concentrations of marine debris in the deep ocean



University of Barcelona

Marine litter has already reached the deepest point in the Mediterranean Sea 

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The bottom of the Calypso Deep, a 5,112-metre deep depression in the Ionian Sea, contains one of the highest concentrations of marine debris in the deep ocean: it is yet another testimony to the increasingly worrying human footprint that has turned seas and oceans into a vast waste dump.

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Credit: Caladan Oceanic




Waste generated by human activities has now reached the deepest point in the Mediterranean: the 5,112-metre-deep Calypso Deep in the Ionian Sea. A total of 167 objects — mainly plastics, glass, metal and paper — have been identified at the bottom, of which 148 are marine debris and 19 others are of possible anthropogenic origin. These results represent one of the highest concentrations of marine litter ever detected at great depths.

These findings are presented in an article published in Marine Pollution Bulletin. The article’s main authors are Miquel Canals, from the University of Barcelona’s Faculty of Earth Sciences; Georg Hanke, from the European Commission’s Joint Research Centre (JRC); François Galgani, from the French Research Institute for Exploitation of the Sea (IFREMER), and Victor Vescovo, from the American company Caladan Oceanic.

To reach the bottom of the trench — the most critical aspect of the entire study — the team used a high-tech manned submarine, the Limiting Factor, a deep-submergence vehicle (DSV). The images provided by the Limiting Factor confirm that, in addition to accumulating on coasts, surface waters and shallower bottoms, marine litter also reaches the deepest and most remote points of the Mediterranean, a sea that is particularly affected by human activities.

The debris identified by the international team in the Calypso Deep warns of the need to implement global policy actions to reduce ocean waste, as well as to encourage changes in citizens’ consumption habits and waste reduction in order to protect seas and oceans around the world.

Marine debris in the deepest Mediterranean Sea

The Calypso Deep is a depression located 60 kilometres west of the Peloponnese coast in Greece, within the so-called Hellenic Trench, with several similar but shallower depressions. Located in an area of high seismicity due to active faults, it is surrounded by fairly steep, stepped relief and has slopes of thousands of metres, and a virtually flat bottom. The inner part of the trench, more than 5,000 metres deep, is kidney-shaped and measures approximately 20 km by 5 km.

But how did the rubbish get so deep? The debris at the bottom of the Calypso Deep “comes from various sources, both terrestrial and marine. It could have arrived by various routes, including both long-distance transport by ocean currents and direct dumping”, explains Miquel Canals, professor at the Department of Earth and Ocean Dynamics and director of the UB Chair on Sustainable Blue Economy. “Some light waste, such as plastics, comes from the coast, from where it escapes to the Calypso Deep, just 60 kilometres away. Some plastics, such as bags, drift just above the bottom until they are partially or completely buried, or disintegrate into smaller fragments” he says.

“We have also found evidence of the boats’ dumping of bags full of rubbish, as revealed by the pile-up of different types of waste followed by an almost rectilinear furrow. Unfortunately, as far as the Mediterranean is concerned, it would not be wrong to say that “not a single inch of it is clean”, warns the expert. The Calypso Trench traps and accumulates the anthropogenic materials that reach it at the bottom: “It is a closed depression, which favours the accumulation of debris inside it. The weak currents in the trench — about two centimetres per second and, exceptionally, 18 — also facilitate the deposition of light debris at the bottom”.

The currents carry floating debris mainly from the southern Ionian Sea and from marine areas further south. Surface eddies also tend to form, concentrating the debris inland. “When these eddies are located over the Calypso Trench, some debris tends to fall slowly to the bottom, aided by degradation mechanisms and ballasting processes that increase its density. Surface currents can also transport debris from the Adriatic Sea to the north, through the Strait of Otranto, and from the waters off north-western Greece”.

The Limiting Factor: cutting-edge technology for deep-sea exploration

Accessing the deepest sea basins is a huge challenge that requires the use of cutting-edge technology. In this case, the innovation is the Limiting Factor submarine, built by Triton Submarines. This vehicle, which is deployed from specially prepared mother ships, is capable of carrying two passengers to the deepest ocean trenches. During the inspection of the seabed, this unique technological device moves slowly — about 1.8 kilometres per hour — to obtain good quality images.

In the Calypso Deep, the Limiting Factor was able to cover a distance equivalent to 650 metres in a straight line, during a 43-minute stay near the bottom. “On each dive, more time is usually spent descending and ascending the vehicle back to the surface than inspecting the bottom. Each complete dive usually takes a few hours”, Canals notes.

This technology has made it possible to calculate the density of marine litter at the bottom of the trench, although no significant impacts on marine life have been detected, as it is particularly impoverished in this chasm of the Ionian Sea. The images only revealed the presence of the species Coryphaenoides mediterraneus, a fish of the macrouridae family, and the decapod Acanthephyra eximia.

“However, in places with more biodiversity, there are different types of interaction between the debris deposited on the bottom and the organisms, such as ghost fishing, burial, hooking or ingestion, but also the use of debris as a substrate where animals can grow, hide or lay their eggs”, Canals notes.

The Mediterranean is one of the most polluted seas by marine debris

The first evidence of debris on the world’s seabed dates back to 1975, in the Skagerrak Strait in the North Atlantic. Canyons and seamounts are the major accumulation points for debris, which can be buried, crumbled or moved by gravity, ocean currents and other oceanographic factors.

Today, the Mediterranean is a marine region particularly affected by this environmental problem. In 2021, a study already identified the Strait of Messina as the area with the highest known density of marine litter in the world (Miquel Canals et al., Environmental Research Letters). This is a real hotspot where large quantities of waste accumulate.

“The Mediterranean is an enclosed sea, surrounded by humanity, with intense maritime traffic and widespread fishing activity. The evidence provided by our research should shake up global efforts, and in particular in the Mediterranean, to mitigate waste dumping, especially plastics, in the natural environment and ultimately in the sea, in line with the UN Global Plastics Treaty against plastic pollution, which is still pending approval. Even the papal encyclical Laudato si’ of May 2015 goes in this direction, as well as some declarations of the G7 world summits, although we are still far from achieving a great social echo in terms of seabed litter”, Canals notes.

Unlike other popular places, such as beaches or the coastline, “the ocean floor is still largely unknown to society as a whole, which makes it difficult to raise social and political awareness about the conservation of these spaces”, the expert continues. “It is necessary to make a joint effort between scientists, communicators, journalists, the media, influencers and other people with social impact. The problem is there, and it has an enormous scope, even if it is not directly visible. We should not forget about it”, concludes Miquel Canals.


The debris at the bottom of the Calypso Deep comes from various sources, both terrestrial and marine.

The debris identified by the international team in the Calypso Deep warns of the need to implement global policy actions to reduce ocean waste, as well as to encourage changes in citizens’ consumption habits and waste reduction in order to protect seas and oceans around the world.


The Limiting Factor submarine is capable of carrying two passengers to the deepest ocean trenches.



Credit

Caladan Oceani


 

Delhi air pollution worse than expected as water vapour skews figures




University of Birmingham






New Delhi's air pollution is more severe than previously estimated with particles absorbing atmospheric water vapour leading to particulate matter levels across the city being underestimated by up to 20%, a new study reveals. 

Hygroscopic growth causes fine particulate matter (PM1) to swell, reducing sampling devices efficiency and leading to underestimation, with greatest underestimation in estimated concentrations happening during winter morning rush hours, when humidity is highest and pollution is most severe.  

In contrast, research shows that the monsoon season shows negligible bias due to the washout of hygroscopic particles by heavy rainfall - the bias is more pronounced during high pollution episodes, with underestimation increasing exponentially with humidity. 

Publishing the findings today (12 Mar) in NPJ Clean Air, study author Dr Ying Chen, from the University of Birmingham, concludes that PM1 pollution in the city is worse than previously thought, but provides correction tools for future studies to better estimate particulate levels. 

Dr Chen commented: “This study highlights the true extent of air pollution in New Delhi and offers a framework for more accurate future assessments that better inform public health strategies and mitigation efforts.  When carrying out air quality assessments, it is crucial to consider hygroscopic growth and the potential for significant underestimation of pollution levels in humid conditions.” 

Biased measurements due to hygroscopic growth are significant in New Delhi due to the high-water content of its aerosol particles, which can contain up to 740 µg/m³ of water and is the highest in megacities all over the world.  

The study suggests that controlling emissions from biomass burning and residential sources, which emits highly hygroscopic chlorine species, could effectively improve air quality and reduce this bias, therefore improve air quality understanding as well. Dr Chen calls for more in-situ observations of PM2.5 and PM10 to gain a more rounded understanding of air pollution in New Delhi.  

There are several seasonal variations identified in the study: 

  • Winter (December to January): The most significant underestimation (up to 20%) occurs during the morning rush hour (8-9 am) due to high humidity (90%) and a shallow planetary boundary layer - the lowest part of the atmosphere, where the surface of the Earth affects the wind, temperature, and moisture.  

  • Spring (February to March): The second highest variance occurs during the morning rush hour with an average relative humidity (RH) of 80%, leading to an 8.6% underestimation. 

  • Monsoon (July to September): Despite high humidity (85%), bias is minimal due to the washout of hygroscopic particles by frequent rain. 

  • Summer (April to June): The driest season with RH between 28% and 50%, resulting in negligible bias due to limited hygroscopic growth. 

New Delhi is recognized as the world’s most polluted capital city, with severe air quality issues threatening the health of its 33 million residents. Particulate matter is the dominant pollutant, responsible for approximately 10,000 premature deaths annually. The World Health Organization (WHO) reports that New Delhi's PM1 levels are 24 times higher than recommended safe levels, even though based on the underestimated observations.  

ENDS 

For more information or an embargoed copy of the research paper, please contact Tony Moran, International Communications Manager, University of Birmingham on +44 (0)782 783 2312 or t.moran@bham.ac.uk. For out-of-hours enquiries, please call +44 (0) 121 414 2772. 

Notes to editor: 

  • The University of Birmingham is ranked amongst the world’s top 100 universities institutions. Its work brings people from across the world to Birmingham, including researchers, teachers and more than 8,000 international students from over 150 countries.  

  • ‘Air pollution in New Delhi is more severe than observed due to hygroscopicity-induced bias in aerosol sampling’ - Ying Chen is published in NPJ Clean Air. 

 

Wrong on skin cares: keratinocytes, not fibroblasts, make collagen for healthy skin




Keratinocytes produce collagen fibers, while deeper fibroblasts later modify the collagen fibers initially formed by keratinocytes



Okayama University

Axolotl, an amphibian with a natural ‘glass skin’ 

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Axolotl is an animal model widely used in dermatology research due to its transparent ‘glass skin.’ A study by researchers from Okayama University, Japan, discovered that healthy collagen fibers, which maintain good skin texture and appearance, are produced by the outer skin cells called keratinocytes rather than the support cells called fibroblasts that help in skin repair, as previously thought.

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Credit: Professor Akira Satoh from Okayama University, Japan




The skin consists of two primary layers. The epidermis, the outermost layer, is predominantly made up of keratinocytes, while the deeper dermis contains blood vessels, nerves, and structural proteins such as collagen, which give the skin its strength and texture. Traditionally, fibroblasts—specialized supporting cells within the dermis—have been believed to play a key role in producing collagen.

In humans, collagen is formed before and after birth. It has been believed that fibroblasts play an exclusive role in collagen production in the skin, and no keratinocytes contribute to collagen production. The statement “Collagen production in the human skin is achieved by fibroblasts” has been an unspoken agreement in the skin research field.

However, in a groundbreaking study published in Volume 16 of Nature Communications on February 24, 2025, scientists from Okayama University, Japan, challenged this long-standing belief. Using the transparent skin of axolotls, an aquatic amphibian widely used in dermatology research, they uncovered a different mechanism for dermal collagen formation.

To track collagen development, the researchers examined axolotl skin at different growth stages—5 cm, 8 cm, 10 cm, and 12 cm in length—using advanced fluorescence-based microscopy techniques. At 5 cm, the axolotl’s skin consisted of an epidermis with keratinocytes and a thin, fibroblast-free collagen layer in the dermis, which they named the stratum coniunctum. As the axolotl grew, the collagen layer thickened, and only later did fibroblasts begin migrating into it, eventually forming three distinct dermal layers beneath the epidermis: the stratum baladachinumstratum spongiosum, and stratum compactum. Each of these layers had a unique collagen structure, none of which matched the original pattern of the stratum coniunctum.

Since collagen was already present before fibroblasts start contributing the dermal collagen formation, the team searched for the source of collagen production by a novel collagen labeling technique that can clarify newly synthesized collagen fibers. The results were surprising: strong fluorescent signals were detected in collagen fibers made by keratinocytes, not fibroblasts. “So far, fibroblasts have been thought to be the major contributors to skin collagen. All efforts in cosmetic science and skin medical research have focused on fibroblast regulation. But the present study demands a change in mindset. We clarified that keratinocytes are primarily responsible for dermal collagen formation,” explains Ayaka Ohashi, a Ph.D. student at the Graduate School of Environmental, Life, Natural Science, and Technology at Okayama University.

Further investigation revealed that keratinocytes produce collagen in a structured, grid-like arrangement on their undersurface. Later, fibroblasts, which have a lattice-like structure and finger-like projections, migrated into this collagen layer, modifying, and reinforcing it. To confirm that this process is not unique to axolotls, the researchers examined other vertebrate models, including zebrafish, chick embryos, and mammalian (mouse) embryos. Their findings were consistent across all species, suggesting that keratinocyte-driven collagen production is an evolutionarily conserved mechanism.

Understanding how collagen forms before birth is crucial for addressing skin aging and developing new treatments for collagen-related conditions. “Axolotls can maintain good skin texture and appearance for a long time. I mean, they have a sort of eternal youth,” says Professor Akira Satoh from Okayama University. “This might be because they continue producing collagen in keratinocytes for a long time. On the other hand, we humans cannot maintain collagen production in keratinocytes after birth. If we can clarify the mechanism that allows axolotls to keep keratinocytes producing collagen throughout their lifetime, we might be able to achieve eternal youth, just like axolotls.”

This discovery reshapes our understanding of skin biology and could lead to breakthroughs in regenerative medicine, wound healing, and cosmetic formulations. Current skincare products primarily target fibroblast activity, but future treatments may need to focus on stimulating keratinocyte-driven collagen production instead.

By overturning a decades-old belief, this research paves the way for a new era in skincare science—one that could bring us closer to maintaining youthful, resilient skin for a lifetime.

 

About Okayama University, Japan

As one of the leading universities in Japan, Okayama University aims to create and establish a new paradigm for the sustainable development of the world. Okayama University offers a wide range of academic fields, which become the basis of the integrated graduate schools. This not only allows us to conduct the most advanced and up-to-date research, but also provides an enriching educational experience.

Website: https://www.okayama-u.ac.jp/index_e.html

 

About Professor Akira Satoh from Okayama University, Japan

Dr. Akira Satoh is a faculty of the Graduate School of Environmental, Life, Natural Science, and Technology at Okayama University, Japan. He has a total of 68 publications to his name, with his primary focus being Life Sciences and Developmental Biology. He works on amphibian limb models to understand why humans have lost their ability to regenerate organs. He was conferred ‘The Young Scientists’ Prize – 2015’ by the Minister of Education, Culture, Sports, Science, and Technology, Japan.

 

About Ayaka Ohashi from Okayama University, Japan

Ayaka Ohashi is a Ph.D. student at the Graduate School of Environmental, Life, Natural Science, and Technology at Okayama University, Japan. She works with amphibian animal models, primarily axolotl to gain deeper insights into various aspects of developmental biology, with 9 publications to her credit. Her recent works were focused on skin, muscle, and limb regeneration.

 

New membrane discovery makes possible cleaner lithium extraction



University of Birmingham





Researchers have developed a new process for sustainable lithium extraction, which could help to address the growing global demand for the metals used in electric vehicle batteries and renewable energy storage. 

Current ways of getting lithium are bad for the environment and more sustainable approaches are hard to perform on a large scale, but scientists have developed new membranes to pull lithium directly out of salty lake water using electricity, leaving other metal ions behind. 

Publishing their findings in Nature Water today (12 Mar), the international group of researchers from the UK, France, and China reveal that the process offers a promising alternative to traditional lithium extraction methods. 

Co-author Professor Melanie Britton, from the University of Birmingham, commented: “There is a critical demand for more-sustainable processes addressing the global challenges of mineral availability and clean water supply, which lead to a circular economy.

“We believe our findings could lead to more efficient and sustainable lithium extraction, which is crucial for the batteries powering everyday devices such as smartphones, laptops, and electric vehicles.” 

The new filtration membranes enable direct lithium extraction from salt-lake brines through a selective electrodialysis process – efficiently separating lithium ions from other ions present in the brine. 

Dr. Qilei Song, from Imperial College London who lead the work, commented: "Our research could reduce the environmental impact of lithium mining and contribute to the development of more efficient energy storage systems for renewable energy sources. There may also be applications in other areas of resource recovery – for example, critical metal recovery from wastewater, plastic and battery recycling.”  

These novel filters can tell the difference between ions with one electrical charge (monovalent) and those with two charges (divalent) - making them very good at separating different types of salt ion.  

The membranes use very tiny channels, smaller than a nanometer (a billionth of a meter) lined with special chemical groups that interact with the ions as they pass through. PhD student Louie Lovell in Prof Britton’s team applied pulsed field gradient nuclear magnetic resonance (PFG-NMR) technique to characterize the water and ion diffusion in the subnanometer channels in the membranes.

They found that the water diffusion co-efficients strongly depend on the channel sizes and the chemical groups within the membranes.  These membranes can produce very pure lithium carbonate (Li2CO3), which is good enough quality to be used in batteries.  

ENDS 

For more information, please contact Tony Moran, International Communications Manager, University of Birmingham on +44 (0)782 783 2312 or t.moran@bham.ac.uk. For out-of-hours enquiries, please call +44 (0) 7789 921 165. 

Notes to editor: 

  • The University of Birmingham is ranked amongst the world’s top 100 universities institutions. Its work brings people from across the world to Birmingham, including researchers, teachers and more than 8,000 international students from over 150 countries.  

  • ‘Solution-processable polymer membranes with hydrophilic subnanometre pores for sustainable lithium extraction’ - Dingchang Yang, Yijie Yang, Toby Wong, Sunshine Iguodala, Anqi Wang, Louie Lovell, Fabrizia Foglia, Peter Fouquet, Charlotte Breakwell, Zhiyu Fan, Yanlin Wang, Melanie M. Britton, Daryl R. Williams, Nilay Shah, Tongwen Xu, Neil B. McKeown, Maria-Magdalena Titirici, Kim E. Jelfs, and Qilei Song is published in Nature Water. 

  • Participating institutions: Imperial College London; University of Birmingham; University College London; University of Edinburgh; Institut Laue Langevin, Grenoble, France; and University of Science and Technology of China, Hefei.