Wednesday, March 19, 2025

 

A squirrel-inspired robot that can leap from limb to limb



Based on studies of leaping squirrels, researchers design a robot that can stick a landing on a branch




University of California - Berkeley

Squirrel-inspired robot sticks a landing 

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Top photo: A free-ranging squirrel leaps from one branch to a branch instrumented to measure force. (Image credit: Sebastian Lee). Bottom photo: A one-legged robot, called Salto, was modified to jump from one branch-like perch to another using principles derived from studies of leaping squirrels. (Image credit: Justin Yim).

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Credit: Sebastian Lee and Justin Yim





Engineers have designed robots that crawl, swim, fly and even slither like a snake, but no robot can hold a candle to a squirrel, which can parkour through a thicket of branches, leap across perilous gaps and execute pinpoint landings on the flimsiest of branches.

University of California, Berkeley, biologists and engineers are trying to remedy that situation. Based on studies of the biomechanics of squirrel leaps and landings, they have designed a hopping robot that can stick a landing on a narrow perch.

The feat, to be reported in the March 19 issue of the journal Science Robotics, is a big step in the design of more agile robots, ones that can leap among the trusses and girders of buildings under construction or robots that can monitor the environment in tangled forests or tree canopies.

"The robots we have now are OK, but how do you take it to the next level? How do you get robots to navigate a challenging environment in a disaster where you have pipes and beams and wires? Squirrels could do that, no problem. Robots can't do that," said Robert Full, one of paper’s senior authors and a professor of integrative biology at UC Berkeley.

"Squirrels are nature's best athletes,” Full added. “The way that they can maneuver and escape is unbelievable. The idea is to try to define the control strategies that give the animals a wide range of behavioral options to perform extraordinary feats and use that information to build more agile robots."

Justin Yim, a former UC Berkeley graduate student and co-first author of the paper, translated what Full and his biology students discovered in squirrels to Salto, a one-legged robot developed at UC Berkeley in 2016 that could already hop and parkour and stick a landing, but only on flat ground. The challenge was to stick the landing while hitting a specific point — a narrow rod.

"If you think about trying to jump to a point — maybe you're doing something like playing hopscotch and you want to land your feet in a certain spot — you want to stick that landing and not take a step," explained Yim, now an assistant professor of mechanical science and engineering at the University of Illinois, Urbana Champaign (UIUC). "If you feel like you're going to fall over forward, then you might pinwheel your arms, but you'll also probably stand up straight in order to keep yourself from falling over. If it feels like you're falling backward and you might have to sit down because you're not going to be able to quite make it, you might pinwheel your arms backward, but you're likely also to crouch down as you do this. That is the same behavior that we programmed into the robot. If it's going to be swinging under, it should crouch. If it's going to swing over, it should extend out and stand tall."

Using these strategies, Yim is embarking on a NASA-funded project to design a small, one-legged robot that could explore Enceladus, a moon of Saturn, where the gravity is one-eightieth that of Earth, and a single hop could carry the robot the length of a football field.

The new robot design is based on a biomechanical analysis of squirrel landings detailed in a paper accepted for publication in the Journal of Experimental Biology and posted online Feb. 27. Full is senior author and former graduate student Sebastian Lee is first author of that paper.

Mixing biology and robotics

Salto, short for Saltatorial Agile Locomotion on Terrain Obstacles, originated a decade ago in the lab of Ronald Fearing, now a Professor in the Graduate School in UC Berkeley’s Department of Electrical Engineering and Computer Sciences (EECS). Much of its hopping, parkouring and landing ability is a result of a long-standing interdisciplinary collaboration between biology students in Full's Polypedal Lab and engineering students in Fearing's Biomimetic Millisystems Lab.

During the five years Yim was a UC Berkeley graduate student  — he got his Ph.D. in EECS in 2020, with Fearing as his adviser — he met with Full's group every other week to learn from their biology experiments. Yim was trying to leverage Salto's ability to land upright on a flat spot, even outdoors, to get it to hit a specific target, like a branch. Salto already had a motorized flywheel, or reaction wheel, to help it balance, much the way humans wheel their arms to restore balance. But that wasn't sufficient for it to stick a direct landing on a precarious perch. He decided to try reversing the motors that launch Salto and use them to brake when landing.

Suspecting that squirrels did the same with their legs when landing, the biology and robotics teams worked in parallel to confirm this and show that it would help Salto stick a landing. Full's team instrumented a branch with sensors that measured the force perpendicular to the branch when a squirrel landed and the torque or turning force with respect to the branch that the squirrel applied with its feet.

The research team found, based on high-speed video and sensor measurements, that when squirrels land after a heroic leap, they basically do a handstand on the branch, directing the force of landing through their shoulder joint so as to stress the joint as little as possible. Using pads on their feet, they then grasp the branch and twist to overcome whatever excess torque threatens to send them over or under the branch.

"Almost all of the energy — 86% of the kinetic energy — was absorbed by the front legs," he said. "They're really doing front handstands onto the branch, and then the rest of it follows. Then their feet generate a pull-up torque, if they're going under; if they are going to go over the top — they're overshooting, potentially — they generate a braking torque."

Perhaps more important to balancing, however, they found that squirrels also adjust the braking force applied to the branch when landing to compensate for over- or undershooting.

"If you're going to undershoot, what you can do is generate less leg-breaking force; your leg will collapse some, and then your inertia is going to be less, and that will swing you back up to correct," Full said. "Whereas if you are overshooting, you want to do the opposite — you want to have your legs generate more breaking force so that you have a bigger inertia and it slows you down so that you can have a balanced landing."

Yim and UC Berkeley undergraduate Eric Wang redesigned Salto to incorporate adjustable leg forces, supplementing the torque of the reaction wheel. With these modifications, Salto was able to jump onto a branch and balance a handful of times, despite the fact that it had no ability to grip with its feet, Yim said.

"We decided to take the most difficult path and give the robot no ability to apply any torque on the branch with its feet. We specifically designed a passive gripper that even had very low friction to minimize that torque," Yim said. "In future work, I think it would be interesting to explore other more capable grippers that could drastically expand the robot's ability to control the torque it applies to the branch and expand its ability to land. Maybe not just on branches, but on complex flat ground, too."

In parallel, Full is now investigating the importance of the torque applied by the squirrel's foot upon landing. Unlike monkeys, squirrels do not have a usable thumb that allows a prehensile grasp, so they must palm a branch, he said. But that may be an advantage.

"If you're a squirrel being chased by a predator, like a hawk or another squirrel, you want to have a sufficiently stable grasp, where you can parkour off a branch quickly, but not too firm a grasp," he said. "They don't have to worry about letting go, they just bounce off."

One-legged robots may sound impractical, given the potential for falling over when standing still. But Yim says that for jumping really high, one leg is the way to go.

"One leg is the best number for jumping; you can put the most power into that one leg if you don't distribute that power among multiple different devices. And the drawbacks you get from having only one leg lessen as you jump higher," Yim said. "When you jump many, many times the height of your legs, there's only one gait, and that is the gait in which every leg touches the ground at the same time and every leg leaves the ground at approximately the same time. So at that point, having multiple legs is kind of like having one leg. You might as well just use the one."

Other co-authors of the Science Robotics paper are Fearing and former UC Berkeley undergraduate Eric Wang, now a graduate student at MIT, and former graduate student Nathaniel Hunt, now an associate professor at the University of Nebraska in Omaha. Co-authors of the J. Exp. Bio. paper are Wang, Hunt, Fearing, UC Berkeley Associate Professor of Mechanical Engineering Hannah Stuart and former UC Berkeley undergraduates Stanley Wang and Duyi Kuang. The research was funded by the U.S. Army Research Office (W911NF-18-1-0038, W911NF-1810327) and the National Institutes of Health (P20GM109090).


Monopedal robot jumping from b [VIDEO] 

Justin Yim describes the success of a monopedal robot, Salto, in leaping from branch to branch thanks to principles of balance control learned from the study of leaping squirrels.

Credit

Justin Yim, with footage from Marc Knight, pexels.com



Berkeley researchers trained t [VIDEO] 

UC Berkeley researchers modified a one-legged robot, called Salto, to jump from one branch-like perch to another using principles derived from studies of leaping squirrels.

Credit

Video by Patrick Farrell, UC Berkeley. Video footage by Justin Yim, University of Illinois, Urbana Champaign.

 

US Endocrine Society calls for restoration of Diabetes Prevention Program



Three decades of diabetes research ended by government funding cuts


The Endocrine Society





WASHINGTON—Three decades of landmark research into type 2 diabetes prevention abruptly ended this month due to government funding cuts.

The Endocrine Society calls on the administration to restore the Diabetes Prevention Program (DPP) and DPP Outcomes Study funded through the National Institutes of Health.

The Society is concerned about how the loss of this ongoing research, which is being conducted at 30 institutions in 21 states, will impact tens of millions of people who have diabetes and prediabetes nationwide. The Society is the largest professional organization for clinicians who treat and scientists who study diabetes and other hormone health conditions.

The DPP, which started in 1996, found that lifestyle changes or taking the medication metformin could prevent or delay the onset of type 2 diabetes in people at risk of developing the condition. The study demonstrated that a 5%-7% weight loss lowered the risk of developing diabetes by 58%.

The DPP Outcomes Study is the long-term follow-up study of the DPP cohort, and is currently studying Alzheimer’s disease and dementia, in addition to continuing to study the long-term effects of diabetes prevention on other health conditions, such as cancer, heart disease and stroke, nerve damage, kidney disease and eye disease. It has continued to follow many of the more than 3,100 surviving DPP participants since 2002.

The research provides an important source of long-term information on diabetes prevention. According to the U.S. Centers for Disease Control and Prevention (CDC), an estimated 38.4 million people in the United States had diabetes as of 2021. That is 11.6% of the population. Another estimated 97.6 million U.S. adults had prediabetes as of 2021.

Preventing and delaying the onset of diabetes can help reduce other chronic conditions, such as heart and kidney disease, and control health care costs. The direct and indirect costs of treating diagnosed cases of diabetes nationwide total an estimated $413 billion in 2022, according to the CDC. Eliminating the Diabetes Prevention Program contradicts the country’s commitment to addressing chronic disease and making America healthy.
 

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Endocrinologists are at the core of solving the most pressing health problems of our time, from diabetes and obesity to infertility, bone health, and hormone-related cancers. The Endocrine Society is the world’s oldest and largest organization of scientists devoted to hormone research and physicians who care for people with hormone-related conditions.

The Society has more than 18,000 members, including scientists, physicians, educators, nurses and students in 122 countries. To learn more about the Society and the field of endocrinology, visit our site at www.endocrine.org. Follow us on X at @TheEndoSociety and @EndoMedia.


 

COVID-19: Lessons learned at the 5-year mark




Columbia University's Mailman School of Public Health

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March 19, 2025-- As New York City marks five years since the first confirmed case of COVID-19, the NYC Preparedness & Recovery Institute (PRI) is reflecting on the city’s response to the COVID-19 public health emergency and pandemic. A newly published article, COVID-19, Five Years Later: What We’re Learning About NYC’s Societal Response to Emergencies, outlines interim insights from PRI’s ongoing COVID-19 Review, which draws from hundreds of reports, interviews, and community discussions to assess the city’s response and identify strategies to strengthen emergency preparedness moving forward.

Launched in 2022, PRI is a resource that advances preparedness, builds resilience, and promotes public health throughout the five boroughs of NYC and around the globe.

Key report findings on the role of mutual aid networks in emergency response include:

  • Strengthening protections for essential workers
  • Rebuilding public trust in health authorities
  • Combating misinformation and addressing health inequities
  • Economic resilience strategies for small businesses and marginalized communities
  • The need for ongoing, sustained public health funding
  • Preventing prejudice and discrimination during public health crises
     

PRI faculty can discuss key findings on:

  • Socio-cultural and Environmental Factors influencing diseases in immigrant and Latino populations.
  • Racial Equity and Social Determinants of Health including breast cancer etiology and health disparities.
  • Workforce Capacity and Preparedness covering occupational health, exposure science, and industrial hygiene; response evaluation, and risk communication.
  • Community Health centering on communication, health literacy, and strategic diplomacy.
  • Epidemiology and Modeling Expert in infectious disease transmission, environmental determinants, and disease forecasting.
     

For more information or to arrange interviews, please contact ICAP Communications at icap-communications@cumc.columbia.edu. For more details, visit pri.nyc.

The New York City (NYC) Pandemic Response Institute (PRI) is a resource supporting New York City agencies, organizations, and communities to prepare and respond to critical public health crises

Columbia University Mailman School of Public Health

Founded in 1922, the Columbia University Mailman School of Public Health pursues an agenda of research, education, and service to address the critical and complex public health issues affecting New Yorkers, the nation and the world. The Columbia Mailman School is the third largest recipient of NIH grants among schools of public health. Its nearly 300 multi-disciplinary faculty members work in more than 100 countries around the world, addressing such issues as preventing infectious and chronic diseases, environmental health, maternal and child health, health policy, climate change and health, and public health preparedness. It is a leader in public health education with more than 1,300 graduate students from 55 nations pursuing a variety of master’s and doctoral degree programs. The Columbia Mailman School is also home to numerous world-renowned research centers, including ICAP and the Center for Infection and Immunity. For more information, please visit www.mailman.columbia.edu.

 

 

Study sheds light on non-urgent visits to US emergency departments



New research reveals gaps between the reasons patients give for their visit, their actual need for care and their final diagnosis




Texas A&M University





Emergency departments in the United States have more than 140 million visits each year — a rate of four visits for every 10 people — that cost nearly $80 billion. Each interaction is carefully documented, including the reasons the patient gives for the visit upon arrival and the diagnosis for the illness or injury the doctor reports when the patient is discharged.

But how often do doctors and patients agree about how serious the situation is based on what the patient says when they arrive?

Not as often as you might think. A new, cross-sectional study found that emergency department doctors and patients agree on the urgency level only about 38 percent to 57 percent of the time. The research, by Benjamin Ukert with the Texas A&M University School of Public Health and colleagues at the University of Alabama at Birmingham and University of South Carolina, was published in the journal of the American Medical Association.

“This is important because nearly 40 percent of emergency department visits are not medical emergencies, which is very costly financially and in terms of staffing and other hospital resources,” Ukert said. “As a result, state legislatures and health insurers have implemented policies to transfer less-urgent cases to doctors’ offices and urgent care centers, but clinicians face profound challenges in making this decision based on what patients tell them about their condition.”

This legal process — retrospective review and adjudication — is based on medical claims and algorithms related to discharge diagnoses and can be used to decide whether insurance pays for emergency care.

“Our findings fundamentally challenge this plan design because if patients and doctors provide different evaluations of the urgency of the condition, then incentives to reduce emergency room visits may not be effective,” Ukert said. “For example, if patients could go to a primary care doctor but payment policies rely on reviewing the patient’s diagnosis and treatment after the visit to determine whether the physician assessed the condition correctly, then this would require patients to know that their condition could be treated in a doctor’s office instead of an emergency department.”

To shed light on concerns about the use of retrospective review for emergency departments, the researchers characterized visits to high-level groups based on the medical urgency of the presenting reasons for visit and to explore the concordance between discharge diagnoses and reasons for visit. They mapped all possible discharge diagnoses to the same reasons for visit for 190.7 million emergency department visits among adults aged 18 years or older for 2018 and 2019 using data from the National Hospital Ambulatory Medical Care Survey.

Most emergency room patients were women (57 percent) and had public health insurance, including Medicare (24.9 percent) and Medicaid (25.1 percent). Visits resulted in hospitalization for 13.2 percent of visits.

The researchers found that 38.5 percent of emergency department visits were classified with 100 percent certainty as involving injuries, needing emergency care, being treatable by primary care, not urgent, or related to mental health or substance use disorders, based on discharge diagnoses. In comparison, only 0.4 percent were classified the same way based on the reason patients gave for their visit.

“In sum, we found no association between the reasons patients gave for their visit at the time of arrival at an emergency department, their need for emergency department care and their final discharge diagnosis,” Ukert said.

For example, the team found that even among discharge diagnoses defined and classified as very emergent, such as strokes or heart attacks, the initial reasons given for the visit for these conditions were likewise classified as emergent only 47 percent of the time.

“This underscores the difficulty physicians face in making definitive assessments at the triage level without first evaluating patients, given that a single reason for seeking care could have multiple possible underlying causes,” Ukert said. “Alternatives to discharge diagnoses are needed.”

He said these could include getting additional information from patients upon their arrival at the emergency department, such as their main concern, symptoms and other information like mode of arrival.

“This information could lead to the development of objective tools that could more accurately assess the complexity of these visits,” Ukert said.

By Ann Kellett, Texas A&M University School of Public Health

New study reveals high levels of fusarium mycotoxins in seized cannabis from Arizona and California




Arizona State University
Seized cannabis may not be safe 

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Seized cannabis. A new study found that 16% of the 118 samples tested positive for harmful mycotoxins, posing potential health risks to consumers. This groundbreaking research highlights the unregulated and dangerous nature of black-market cannabis.

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Credit: CDC




A recent study conducted by researchers from Arizona State University has uncovered alarming levels of Fusarium mycotoxins in illicit cannabis samples seized in Arizona and California.

 

The study found that 16% of the 118 samples tested positive for harmful mycotoxins, posing potential health risks to consumers. This groundbreaking research highlights the unregulated and dangerous nature of black-market cannabis.

 

The study, led by Arizona State University professor Maxwell Leung, analyzed cannabis samples obtained between November 2023 and June 2024 from law enforcement seizures. The samples were tested for 23 types of mycotoxins and fungal metabolites.

 

Notably, Fusarium mycotoxins such as fusarenon-X and diacetoxyscirpenol were present at levels exceeding regulatory standards for agricultural products. However, there are no federal or state monitoring or reporting programs for Fusarium contamination in legal and illegal cannabis.

 

“Many Fusarium mycotoxins can contribute to vomiting symptoms in users,” said Leung, an assistant professor in the School of Mathematical and Natural Sciences and study leader. “The presence of Fusarium fungi in cannabis can also pose an infection risk in immune-compromised users.”

 

Key Findings:

 

  • 16% of samples contained detectable levels of mycotoxins.

 

  • Fusarenon-X was found in 10 samples at concentrations ranging from 500 to 1,700 ppb, exceeding typical safety thresholds for food products.

 

  • Several samples contained diacetoxyscirpenol, a federally designated biological select agent and toxin, which presents a significant health concern.

 

  • In contrast, only one sample showed a regulated mycotoxin (ochratoxin A).

 

The research raises public health concerns, as many cannabis users may be unknowingly exposed to these dangerous fungal contaminants, which are linked to symptoms such as vomiting and gastrointestinal distress. Illicit cannabis, which is grown in unregulated environments, is particularly susceptible to contamination due to poor handling, unsanitary conditions, and lack of oversight.

 

Health Implications

Cannabis contaminated with Fusarium mycotoxins may pose serious health risks, particularly for individuals with weakened immune systems or those who consume cannabis for medicinal purposes. Mycotoxins such as fusarenon-X are known to cause vomiting, and their presence in cannabis could potentially exacerbate conditions like cannabis hyperemesis syndrome, which has been linked to increased emergency room visits.

 

While the legal cannabis market is subject to stringent safety testing, the black market remains a major source of unregulated and potentially dangerous products. In 2022, the illicit cannabis market in the U.S. was estimated to be worth $76 billion, more than double the size of the legal market, further emphasizing the public health risk posed by unregulated cannabis sales.

Needs for Future Research

The authors stress the urgent need for further research into the health risks associated with Fusarium contamination in cannabis, particularly regarding inhalation exposure through smoking or vaping, as well as dietary exposure through edibles.

“Despite the legalization effort at the state level, the majority of the cannabis supply remains coming from the black and grey market,” said Leung. “The contaminants in illicit cannabis represent a public health risk that needs to be addressed.”

For more information, the full study, "Evaluation of Fusarium Mycotoxins and Fungal Metabolites in Seized Cannabis in Arizona and California, 2023-2024," can be accessed through Environmental Health Perspectives (DOI 10.1289/EHP16028).