Wednesday, April 16, 2025

 

Iron Age purple dye "factory" in Israel was in operation for almost 500 years, using mollusks in large-scale specialized manufacturing process



PLOS
Tel Shiqmona during the Iron Age: A first glimpse into an ancient Mediterranean purple dye ‘factory’ 

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Hexaplex trunculus shell collected near Tel Shiqmona. 400 such shells were identified by two free-style divers within 90 mins at a depth of one to two meters on October 20, 2020. Photo by Ayelet Gilboa.

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Credit: Shalvi et al., 2025, PLOS One, CC-BY 4.0





 

 

Article URLhttps://plos.io/44elLDX

Article title: Tel Shiqmona during the Iron Age: A first glimpse into an ancient Mediterranean purple dye ‘factory’

Author countries: U.S., Israel

Funding: The author(s) received no specific funding for this work.

Sunscreen, clothes and caves may have helped Homo sapiens survive 41,000 years ago




University of Michigan





ANN ARBOR—Ancient Homo sapiens may have benefitted from sunscreen, tailored clothes and the use of caves during the shifting of the magnetic North Pole over Europe about 41,000 years ago, new University of Michigan research shows.

These technologies could have protected Homo sapiens living in Europe from harmful solar radiation. Neanderthals, on the other hand, appear to have lacked these technologies and disappeared around 40,000 years ago, according to the study, published in Science Advances and led by researchers at Michigan Engineering and the U-M Department of Anthropology.

The team found that the North Pole wandered over Europe when the magnetic field's poles started to flip positions, a natural process that has happened around 180 times over Earth's geological history. While the magnetic reversal didn't complete at the time, the magnetic field weakened to cause aurora to occur over most of the globe, and allowed more harmful UV light to come in from space. 

Around the same time, Homo sapiens appear to have started making tailored clothing and using ochre, a mineral that has sun-protective properties when applied to the skin,  with greater frequency. These behaviors could have contributed to their spread throughout Europe and Asia at a time when the Neanderthal population was declining.

"In the study, we combined all of the regions where the magnetic field would not have been connected, allowing cosmic radiation, or any kind of energetic particles from the sun, to seep all the way in to the ground," said Agnit Mukhopadhyay, lead author and U-M research affiliate in climate and space sciences and engineering. 

"We found that many of those regions actually match pretty closely with early human activity from 41,000 years ago, specifically an increase in the use of caves and an increase in the use of prehistoric sunscreen."

Wandering poles

Earth's magnetic field is created by its rotation, and by extension, the rotation of its core. The core, which is composed of molten iron, generates electrical currents, which extend in a halo around the globe. This halo helps protect Earth from cosmic radiation—the stuff that thins Earth's ozone layer and lets in more UV light. The interaction of these particles with Earth's magnetic field results in aurora as well.

Mukhopadhyay began building models of this interaction using the Space Weather Modeling Framework, a versatile numerical tool developed and maintained by the U-M Center for Space Environment Modeling, to study the sun, heliosphere and planetary space environments, including that of Earth. 

The sun continually throws hot gases and charged particles toward Earth, which, because of their extremely high temperatures, act as a plasma system. Mukhopadhyay developed a model that predicts how this plasma system interacts with Earth's magnetic field, ultimately driving the formation of the aurora.

This magnetic field has a north and south orientation: the North and South poles. The orientation of the magnetic field is why you typically only see aurora at the North and South poles, where magnetic fields are the strongest. But occasionally throughout history, these poles wander from their traditional geographic positions. These are called "geomagnetic excursions," says Mukhopadhyay. The most recent event is called the Laschamps excursion, which occurred about 41,000 years ago.

Working with Sanja Panovska, a researcher at Germany's GFZ Helmholtz Centre for Geosciences, Mukhopadhyay created a 3D reconstruction of Earth's geospace system. To do this, the researchers combined three separate models: one global model that reconstructs the geomagnetic field during the Laschamps excursion, a model of the space plasma environment around Earth, and a model that predicted what Earth's aurora looked like at the time. The resulting 3D model showed where charged particles were able to slip through Earth's geomagnetic field.

The researchers found that during the Laschamps excursion, Earth's magnetic field reduced in size to about 10% of its current strength. This allowed Earth's magnetic poles to droop down near the equator and for its magnetic field lines to expand. This would have also allowed aurora to be seen all over Europe and into northern Africa.

The researchers then laid their 3D map of Earth's space system over the world, and found that the time period of the Laschamps excursion—which lasted from about 41,000 to 39,000 BP—coincided with periods of change for groups of humans living on the planet

Cosmic rays, radiation and survival

Neanderthals and Homo sapiens coexisted in Europe, with Homo sapiens—often called anatomically modern humans—arriving roughly 56,000 years ago, says Raven Garvey, U-M associate professor of anthropology. By about 40,000 years ago, Neanderthals were no longer identified as a species in Europe.

"What some of the differences are between these species, between Neanderthals and anatomically modern humans, that might account for that disappearance has been a major anthropological question for decades," Garvey said.

Clothing may have been a contributing factor, she said. The technological means of producing clothing that fitted to the body has been discovered at archaeological sites associated with anatomically modern humans, but not necessarily Neanderthals. 

However, at sites associated with anatomically modern humans, archaeologists have found not only scrapers used in hide production, but also needles and awls—items associated with sewing. According to Garvey, tailored clothing has a twofold benefit: It was significantly warmer and the added warmth meant that people could travel farther from their hearths and shelters in search of food.

Tailored clothing could have also provided another unintended benefit—protection from sun damage, she said.

There are multiple detrimental effects of solar radiation, including ocular pathologies and folate depletion (which can lead to birth defects and increased infant mortality), "so having protection against solar radiation would also have conferred significant advantage to anyone who possessed it," Garvey said. 

Homo sapiens may have also ramped up their use of ochre, a naturally occurring pigment composed of iron oxide, clay and silica that has been used by many species of hominins for a very long time. People used it to paint objects, cave walls and even to decorate their bodies.

"There have been some experimental tests that show it has sunscreen-like properties. It's a pretty effective sunscreen, and there are also ethnographic populations that have used it primarily for that purpose," Garvey said. "Its increased production and its association primarily with anatomically modern humans (during the Laschamps) is also suggestive of people's having used it for this purpose as well."

Finding caution in the (solar) wind

The researchers are careful to underscore that their findings aren't definitive. However, they are a new way to look at already existing data.

"I think it's important to note that these findings are correlational and (ours is a) meta analysis, if you will," Garvey said. "But I think it is a fresh perspective on these data in light of the Laschamps excursion."

In addition to examining how previous excursions might have affected humans long ago, Mukhopadhyay said the 3D model offers people a way to predict how excursions might affect us in the future.

"If such an event were to happen today, we would see a complete blackout in several different sectors," he said. "Our communication satellites would not work. Many of our telecommunication arrays, which are on the ground, would be severely affected by the smallest of space weather events, not to mention the human impacts which would also play a pretty massive role in our day-to-day lives."

Mukhopadhyay also pointed out that their work also highlights that people were still able to survive on a planet whose atmosphere looked a lot different than ours does today, and this has implications for the search for life on planets other than Earth.

"Many people say that a planet cannot sustain life without a strong magnetic field," he said. "Looking at prehistoric Earth, and especially at events like this, helps us study exoplanetary physics from a very different vantage point. Life did exist back then. But it was a little bit different than it is today."

Study co-authors also include Michael Liemohn, Daniel Welling and Austin Brenner of Michigan Engineering, Natalia Ganjushkina of both Michigan Engineering and the Finnish Meteorological Institute, Ilya Usoskin of the University of Oulu and Mikhail Balikhin of the University of Sheffield.

 

UTA professor explores healing power of music



Inspired by Alzheimer’s-stricken Glen Campbell, UT Arlington’s Rhonda Winegar explores how music therapy can support neurological care



University of Texas at Arlington

Rhonda Winegar 

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“Music delays neurodegeneration in conditions such as Alzheimer’s,” said Rhonda Winegar, UTA assistant professor.

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Credit: UTA




Rhonda Winegar remembers watching the 2014 documentary “I’ll Be Me,” which chronicled country music legend Glen Campbell’s struggles with Alzheimer’s disease. An assistant professor at The University of Texas at Arlington with 25 years of experience as a nurse practitioner in neurology, Winegar was struck by how the disease had stripped away so much of Campbell’s life—yet he could still strum his guitar and sing his songs.

“He kept wandering off, and they’d have to push him back on stage,” Winegar said. “Yet he could still play all those difficult chords and remember the lyrics to his songs. I often recommend that documentary to my patients who are newly diagnosed with Alzheimer’s or dementia—it helps them understand the disease.”

That experience prompted Winegar to research the topic more deeply. While music therapy dates back some 20,000 years, when shamans used ritualistic drumming to ward off disease, Winegar discovered just how effective music can be as a complementary treatment for a range of conditions, including dementia, chronic pain, developmental delays and heart rate regulation.

Related: Inspiration Takes Aim: Wearable music therapy

She partnered with colleague Dustin Hixenbaugh, a professor at San Jacinto College in Pasadena, Texas, to coauthor "Prescribing Music as an Adjunctive Treatment," published in the March 2025 edition of The Journal for Nurse Practitioners.

“Music delays neurodegeneration in conditions such as Alzheimer’s,” Winegar said. “Sometimes, patients with memory issues get anxious and upset, which can start affecting their speech and ability to communicate. But if they’re able to sing, they can express their feelings, which helps reduce anxiety, stress and depression.”

Winegar described two types of music therapy: active, which involves playing an instrument or singing, and passive, which involves simply listening. Both can be beneficial in different situations. A military veteran who served from 1987-2003, Winegar recalls how music helped calm her nerves or gave her a needed boost during a difficult time.

“If you’re running with music playing, it can push you to keep going,” Winegar said. “In a clinical setting, patients dealing with Parkinson’s disease and other movement disorders can improve their walking cadence and frequency just by listening to music.

“In neurology, music has been shown to decrease seizure activity by calming abnormal electrical impulses in the brain. Research also shows that music can regulate heart rate and blood pressure by reducing overexcitation in the nervous system.”

When it comes to the most beneficial types of music, Winegar said it depends entirely on the person. Someone might find heavy metal more calming than country music, or vice versa. Personal preference is key.

Winegar, a country music fan herself, organized her presentation of this research around the genre when she shared her findings at the International Country Music Conference in Nashville last year.

“We focused on how country music can be used in a clinical setting,” she said. “It often tells the stories of struggle—my wife left me, I’m an alcoholic, my truck won’t start. We framed our presentation around the idea that music can serve as a support group, helping people connect with others facing similar struggles.

“At the end of the day, music is a powerful tool,” she continued. “It doesn’t cost anything to turn on the radio, and it can be there for you during rough patches—whether you’re feeling anxious, depressed or in pain. It can motivate you, help you exercise or provide comfort. Music has always been there for us. That’s the most important takeaway from this research.”

 

Even vegans who get enough total protein may fall short for some essential amino acids



In New Zealand study, 3 in 4 vegans ate sufficient protein, but half didn’t meet daily lysine and leucine requirements



PLOS

Evaluation of protein intake and protein quality in New Zealand vegans 

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Variation in vegan dietary patterns and their influence on total protein intake and protein quality using a story of three vegans. Mandy demonstrates the most balanced approach of achieving both high total protein intake and protein quality. Jerry, on the other hand, meets his protein intake but his diet falls short on protein quality. Sandy represents a common pattern observed in our cohort, and her existing diet fails in meeting both protein quantity and protein quality. In summary, our findings show a high protein intake alone does not always guarantee adequate protein quality.

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Credit: Soh et al., CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/)




In a new study of people with long-term vegan diets, most ate an adequate amount of total daily protein, but a significant proportion did not meet required levels of the amino acids lysine and leucine. Bi Xue Patricia Soh and colleagues at Massey University, New Zealand, present these findings in the open-access journal PLOS One on April 16, 2025.

Proteins are made up of various molecular “building blocks” known as amino acids. While the human body can synthesize most of the amino acids we need to live, we completely rely on the food we eat to provide the nine “indispensable amino acids” we cannot make ourselves. Typically, plant-based foods have more varied levels of indispensable amino acids that the body can use, as compared to animal-sourced foods, so they are of particular concern in vegan diets.

However, most prior research on protein in vegan diets has not considered specific amino acids nor the digestibility of different foods, which accounts for the fact that not all of what we eat, including amino acids, is fully utilized by the body.

To help deepen understanding of amino acid intake in vegan diets, Soh and colleagues analyzed detailed, four-day food diaries kept by 193 long-term vegans living in New Zealand. They used information from the United States Department of Agriculture and the New Zealand FoodFiles database to calculate participants’ intake of different amino acids from the different foods they ate.

The analysis showed that about three quarters of participants met daily total protein requirements. Accounting for body weight, intake of all indispensable amino acids also met requirements.

However, when considering digestibility, only about half of the participants met daily requirements for lysine and leucine levels, making them the most limiting indispensable amino acids in the study. Among the food types consumed by participants, legumes and pulses were the biggest contributors to overall protein and lysine intake.

These findings underscore that meeting total daily protein requirements does not necessarily mean meeting indispensable amino acid requirements. On the basis of their findings, the researchers call for future research to explore how intake of leucine and lysine could be boosted for vegans in a nutritionally balanced manner.

The authors add: “Vegan diets are the most restrictive form of plant-based eating, relying entirely on plant sources for all nutrients. Achieving high protein quality on a vegan diet requires more than just consuming enough protein – it also depends on the right balance and variety of plant foods to supply all the amino acids in the quantities that our body needs. Prolonged deficiencies in these essential nutrients can negatively affect overall protein balance, muscle maintenance and other physiological functions, especially in more vulnerable populations.”

“In our study, lysine and leucine were the most commonly under-consumed amino acids in our vegan cohort and fall below the daily requirements needed by our body. This is because many plant foods generally contain lower quantities of these amino acids that can be absorbed and utilized by the body. However, the inclusion of legumes, nuts and seeds emerged as valuable plant sources – not only to support overall protein intake but also to specifically increase lysine and leucine quantities in a vegan diet.”

 

 

Press preview: https://plos.io/4jbLuRI

In your coverage, please use this URL to provide access to the freely available article in PLOS Onehttps://plos.io/42dJMbG

Citation: Soh BXP, Vignes M, Smith NW, von Hurst PR, McNabb WC (2025) Evaluation of protein intake and protein quality in New Zealand vegans. PLoS ONE 20(4): e0314889. https://doi.org/10.1371/journal.pone.0314889

Author countries: New Zealand

Funding: Lottery Health Project Grant (LHR-2022-185) PhD stipend from the Riddet Institute, Massey University.

 

“Ban-the-Box” policy did not effectively help job applicants with criminal records in one analysis


For one employer, “Ban-the-Box” had little impact, suggesting any benefits might depend on the setting



PLOS

Do ban-the-box policies increase the hiring of applicants with criminal records? 

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“Ban-the-Box” policy did not effectively help job applicants with criminal records, according to new study.

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Credit: Elf-Moondance, Pixabay, CC0 (https://creativecommons.org/publicdomain/zero/1.0/)




Analysis of job applicant data from one large employer suggests that a policy meant to improve employment prospects for people with criminal records did not actually lead to changes in job offers for people with records. Deborah Weiss of Northwestern University, U.S., and colleagues present these findings in the open-access journal PLOS One on April 16, 2025.

Parts of the U.S. have introduced “Ban-the-Box” (BTB) laws, which aim to improve job prospects for people with criminal records. BTB policies often include a screening ban prohibiting employers from asking about an applicant’s criminal record until after a conditional job offer, as well as a ban against withdrawal of a conditional offer based on a criminal record unless it is related closely enough to job duties.

Prior research on BTB policies has had mixed results, suggesting they may be effective in some settings but not others. However, due to challenges in obtaining internal employer data, it has been unclear how BTB may affect specific phases of the hiring process beyond initial screening. Now, Weiss and colleagues have completed the first study of BTB looking at later hiring phases.

The researchers statistically analyzed employment data from an academic health science center, covering a period of 25 months before and 52 months after enactment of a BTB policy.

They found that introduction of the policy had little or no statistical association with the rates of conditional employment offers for people with criminal records. In addition, the rate of people with records passing a final background check did not change.

After BTB implementation, in fact, people with certain prior convictions were less likely to be hired, suggesting the possibility that any benefits of a screening ban might be reversed during subsequent candidate assessment. While the study could not confirm any underlying cause-effect relationship, the researchers suggest that hiring managers might, perhaps unintentionally, undo the effects of BTB policies. After enactment of BTB policies, hiring managers might increase reliance on hiring criteria that are correlated with criminal history, such as personality traits, resulting in statistical discrimination, against applicants with criminal records.

It is unclear from the results of the study how well these findings might generalize to similar employers. Nonetheless, they underscore the possibility that the success of BTB policies may depend on the setting.

The authors add: “The most powerful tool we have to reduce recidivism is employment. People with criminal records need real chances to work and rebuild their lives. Public policy cannot limit itself to a single tool like 'ban the box'—it must address the full range of barriers these individuals face when seeking work.”

 

 

In your coverage, please use this URL to provide access to the freely available article in PLOS Onehttps://plos.io/4iHXKJw

Citation: Weiss DM, Dawson W, McKinley R, Webster L (2025) Do ban-the-box policies increase the hiring of applicants with criminal records? PLoS ONE 20(4): e0320736. https://doi.org/10.1371/journal.pone.0320736

Author countries: U.S.

Funding: The author(s) received no specific funding for this work.