Wednesday, December 03, 2025

How Public Finance for Agriculture Can Improve Food Security, Health, and Climate

By supporting agroecology, multilateral development banks can stop fueling harm and start financing a just and sustainable food systems transition.


Agroecology technician Yin Rangel, 49, checks seed and potato crops in one of PROINPA (Productores Integrales del Paramo) greenhouses in Mucuchies in Merida State, Venezuela, on August 4, 2023.
(Photo by Miguel Zambrano / AFP via Getty Images)
Ladd Connell
Dec 03, 2025
Common Dreams

Agriculture is essential to human life. How we feed ourselves matters for nutrition, health, climate, biodiversity, and livelihoods. Nearly 928 million people are employed in farming globally, and food systems are responsible for one-third of global greenhouse gas emissions and most new deforestation.

Multilateral development banks (MDBs), like the World Bank Group (WBG), play a critical role. The WBG has committed to double its agricultural financing to $9 billion a year by 2030. In October it launched AgriConnect, an initiative seeking to transform small-scale farming into an engine of sustainable growth, jobs, and food security.

However, while some MDB investments support equitable and sustainable transformation, too many still fuel environmental destruction and inequity. The World Bank’s private sector arm, IFC, recently invested $47 million in a multi-story pig factory farm in China, for example.

A new report from the University of Vermont Institute for Agroecology analyses MDB agricultural investments and sets out a road map for how banks can support, rather than hinder, sustainable farming. The research finds that the World Bank and other public-sector lenders can drive systemic change by supporting governments with policy reforms, rural extension services, and enabling environments. For example, a $70 million Inter-American Development Bank project in Paraíba, Brazil is promoting inclusive, low-carbon agriculture, and strengthening family farmers and traditional communities through technical assistance and climate-resilient infrastructure.

MDBs’ private sector operations must reform their lending criteria and stop financing destructive projects.

MDBs are better placed than other financial institutions to take long-term, lower-return investments aligned with climate and food security goals. Agroecological farming, a holistic, community-based approach to food systems that applies ecological and social food sovereignty concepts, along with long-term productivity, provides a channel for public sector arms of MDBs to support needed agricultural transformation. MDBs and other public banks therefore, should seek to become the enablers of agroecology. The International Fund for Agricultural Development (IFAD) and the Agence Française de Développement (AFD) are already leading efforts in this direction.
MDB Private Sector Operations: Profit-Driven Harms

In contrast to the IFAD and AFD models, the University of Vermont’s Institute for Agroecology’s report found that the majority of private-focused MDBs prioritize “bankable” projects—typically large-scale, industrial, profit-driven agribusiness. This model steers money toward factory farms that use human-edible food as feed, pollute nearby communities, raise the risks of zoonotic disease and antimicrobial resistance, and engage in animal cruelty. In 2023, a report by Stop Financing Factory Farming found that public finance institutions invested US$2.27 billion in factory farming, 68% of the total investment in animal agriculture projects that year.

As evidenced by multiple complaints from impacted communities, these investments undermine poverty reduction, Sustainable Development Goals (SDGs), and Paris Agreement climate goals. MDBs’ private sector operations must reform their lending criteria and stop financing destructive projects.

The opportunity: Public Sector Banks Can Pave the Way for Private-Sector Transformation

Rich country governments currently subsidize agriculture, mostly industrial, at a level of $842 billion per year. According to the IMF, only a quarter is dedicated to support for public goods in the sector. Shifting this support to incentivize investments in agroecology is crucial to sustain the agricultural transformation that public banks themselves have called for.

Public banks have the opportunity to join a growing number of organisations already advancing an ecological approach to meet the SDGs and wider social, cultural, and economic, and environmental objectives. To do so, they must shift from treating agroecology as merely a niche solution and instead invest in it as a priority means for achieving food systems transformation.

Agroecology puts an end to costly and harmful practices, replacing animal cruelty with humane, safe, and fair standards.

By taking this approach, public banks can better support just transitions in food systems, something that is already beginning to take shape. Earlier this year, for example, the World Bank backed an $800 million loan to the Colombian government to advance a greener and more resilient economic transformation.

The private-sector arms of MDBs, such as IFC and IDB Invest, also have a role to play in aligning with the transition. Most importantly, they can support governments with policy advice and financing criteria that break from entrenched models and exclude industrial animal agriculture from eligibility for finance.

While MDBs have taken steps to make agricultural production and rural incomes less vulnerable to climate change, they have yet to commit to agroecological farming as the most effective pathway. In contrast, IFAD is already demonstrating what this can look like, driving agroecological transitions through private-sector incentives in Ethiopia, Peru, and Vietnam. Similarly, AFD is applying agroecology to support family farming in Ethiopia, Haiti, Madagascar, Malawi, and Sierra Leone.
Agroecology as the Future of Sustainable Farming—and Public Agricultural Finance?

If MDBs are looking to advance the SDGs and solve the polycrisis (climate, biodiversity, pandemic risk, and food security), one of the most effective ways in which this can be done is for the public sector to mobilize policy support and significant capital investment into agroecology. Meanwhile, MDB private sector arms can enable this transition by providing policy advice and finance for interventions that break from entrenched models.

Agroecology puts an end to costly and harmful practices, replacing animal cruelty with humane, safe, and fair standards. But it’s not just about farming practices. It also helps transform food systems, building resilient, reparative, low-emission economies and improves livelihoods in line with the 2030 SDGs.

By supporting agroecology, MDBs can stop fueling harm and start financing a just and sustainable food systems transition. If they are serious about the SDGs, food security, and climate goals, the road map is clear—MDBs’ public sector operations must enable, their private sector operations must reform, and both must support a transition away from industrial agriculture toward a more just and sustainable food system.


Our work is licensed under Creative Commons (CC BY-NC-ND 3.0). Feel free to republish and share widely.


Lizah Makombore
Lizah Makombore is a PhD candidate at the University of Vermont Institute for Agroecology.
Full Bio >

Ladd Connell
Ladd Connell is a multilateral finance consultant at Friends of the Earth.
Full Bio >


Study: Family grocery purchases improved when online grocery carts were preloaded with healthy ingredients



UB-Instacart pilot study increased nutritional quality of groceries of families with young children without increasing grocery costs




University at Buffalo

Stephanie Anzman-Frasca, PhD, led the study 

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Stephanie Anzman-Frasca and her UB colleagues have done pioneering work in behavioral medicine and nutrition, including prior research on optimal defaults; in this study, they wanted to see how the preloaded default grocery carts would work in families with young children at risk for obesity.

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Credit: Sandra Kicman/University at Buffalo





BUFFALO, N.Y. — University at Buffalo researchers have shown that preloading Instacart online grocery carts with healthy ingredients could be a useful tool for improving the diets of families with young kids at risk for obesity.

Published on December 3 in Appetite, the randomized, controlled pilot study found that providing families with healthy recipes and then preloading online grocery carts via Instacart with the ingredients needed to make those recipes resulted in families making purchases that were significantly more nutritious compared to a group that received only the recipes. Families paid for their grocery purchases as usual and were free to switch out pre-loaded cart ingredients if they wanted to.

“The findings support the idea that healthier choices can be supported by making them easier and more automatic,” says Stephanie Anzman-Frasca, PhD, corresponding author on the paper and an associate professor of pediatrics and director of the Child Health and  Behavior Lab in the Jacobs School of Medicine and Biomedical Sciences at UB.

PHOTO: https://www.buffalo.edu/news/releases/2025/12/UB-Instacart-study-family-nutrition-default.html

Research shows that children who are overweight by age 5 are more likely to have obesity later in life, putting them at risk for cardiovascular and other diet-related diseases.

“Since experience with foods and flavors early in life can influence children’s later food preferences, eating behavior and health, it’s important to make healthy choices easier for families with young children,” Anzman-Frasca says.

A ‘real-world’ family shopping intervention

The study was the first time that a default grocery shopping intervention for families with young children was conducted in a real-world scenario, where families were purchasing the actual groceries they would be eating during the four-week study. The goal was to test in a real-world shopping situation the impact of “optimal defaults,” the idea that preselected options can be helpful in guiding people toward healthy behaviors.

Anzman-Frasca and her colleagues in the Division of Behavioral Medicine have done pioneering work in behavioral medicine and nutrition, including prior research on optimal defaults; in this study, they wanted to see how the preloaded default grocery carts would work in families with young children at risk for obesity.

Eligible families had to do at least 75% of their grocery shopping online, and one parent had to have a body mass index of at least 25, classifying them as overweight. A diverse group of 69 families, nearly half of whom were living with lower incomes, participated.

All families received healthy recipes for two weeks, and a sample recipe bundle is included in the published paper. Each weekly bundle included recipes for three dinners, plus a “bonus” recipe, such as a snack, that used leftover ingredients from the dinner meals. While all participating families received the recipes, half of the families had their Instacart online grocery carts preloaded with the ingredients to make those dishes, while the other half did not.

“When faced with making a choice, most people will take the default option unless they’re highly motivated to choose an alternative,” says Mackenzie Ferrante, PhD, a co-author and assistant professor at Rutgers University, who did postdoctoral work at UB. “These days, the easy, or default, choice with food is rarely the healthy option. We wanted to see what would happen if the default option for families was the healthy choice.”

“This real-world study shows how Instacart’s technology can make it easier for families to fill their tables with healthier foods,” says Beatrice Abiero, PhD, senior manager of policy research at Instacart. “By examining how our platform can inspire more nutritious choices, we’re seeing how online grocery can support healthier habits — without adding cost — at scale. We’ll continue to use Instacart Health tools to support research and nutrition programs that help make the healthy choice the easy choice.”

The researchers note that children between the ages of 2 and 5 are frequently afraid of, and resistant to, trying new foods, which can pose a challenge. In this study, recipes were selected for families based on information that they provided about their family’s food preferences at the beginning of the study. Results showed that there was a significantly greater improvement in nutritional quality of families’ grocery purchases in the group that received the preloaded carts compared to the group receiving only the recipes.

‘Eye-opening’ to see what they were spending

Across both groups, families’ spending on groceries decreased over the course of the study. While this wasn’t a main goal of the study, and more research needs to be done, the researchers say it’s possible that the requirement to fill out forms about what they purchased might have made families more aware of superfluous items they were buying. Some participants noted it was eye-opening to see how much they were spending.

In the future, the researchers want to extend the work to examine how the preloaded online grocery carts affect family grocery purchases over a longer time period and corresponding impacts on dietary intake and health. In the meantime, Anzman-Frasca says, families can use the “Buy It Again” feature on Instacart to repurchase healthy ingredients they have enjoyed in the past, which can be used to easily reload those ingredients into future shopping carts.

When this study began in 2023, the White House cited it as an example of how to combat nutrition insecurity and diet-related disease. The project was supported by Instacart and leveraged Instacart Health tools. The support from Instacart complemented an initial investment from the UB Office of the Vice President for Research and Economic Development. UB’s Clinical and Translational Science Institute provided seed funding for prior pilot research that set the stage for the current project.

Additional co-authors include Juliana Goldsmith, Adrianna Calabro, Karlie Gambino and Leonard H. Epstein, PhD, of the Jacobs School; Lucia A. Leone, PhD, and Gregory E. Wilding, PhD, of the UB School of Public Health and Health Professions; and Brianna Wallenhorst of the Independent Health Foundation.

 

Alternative sweetener sorbitol linked to liver disease





Washington University in St. Louis





By Leah Shaffer

Sweeteners such as aspartame, found in Equal packets, sucralose (Splenda), or sugar alcohols are often seen as healthier alternatives to food with refined sugar (glucose).

But that assumption is being challenged with new scientific research, including the recent finding that the sugar alcohol sorbitol is not as harmless a sugar substitute as once thought.

The study, published recently in Science Signaling, follows a line of research detailing the harmful effects of fructose on the liver and other systems from the lab of Gary Patti, at Washington University in St. Louis.

Patti, the Michael and Tana Powell Professor of Chemistry, in Art & Sciences, and of genetics and medicine, at WashU Medicine, previously has published research about how fructose processed in the liver can be hijacked to supercharge cancer cells. Previous research also has found that fructose is a key contributor to steatotic liver disease, affecting 30% of the adult population worldwide.

The most surprising finding from the current work is that because sorbitol is essentially “one transformation away from fructose,” it can induce similar effects, Patti said.

The research involved experiments with zebrafish demonstrating that sorbitol, often used in “low-calorie” candy and gum, and commonly found in stone fruits, can naturally be made by enzymes in the gut and eventually converted into fructose in the liver.

Patti’s team found there are many roads to fructose in the liver, and potential detours, depending on a person’s sorbitol and glucose consumption patterns, along with the bacterial populations colonizing their gut.

For starters, although most of the research on sorbitol metabolism has focused on its production due to glucose overload in pathological settings such as diabetes, sorbitol can be naturally produced in the gut from glucose after eating, Patti said.

The enzyme that produces sorbitol has a low affinity for glucose, so glucose levels must be high for it to take effect. That is why sorbitol production has primarily been associated with diabetes, where blood glucose levels can become elevated. But, even in healthy settings, glucose levels in the gut become high enough after feeding to drive sorbitol production within the intestine, according to the team’s zebrafish experiments.

“It can be produced in the body at significant levels,” said Patti. “But if you have the right bacteria, turns out, it doesn’t matter.”

Sorbitol-degrading Aeromonas bacterial strains convert the sugar alcohol into a harmless bacterial byproduct.

“However, if you don’t have the right bacteria, that’s when it becomes problematic. Because in those conditions, sorbitol doesn’t get degraded and as a result, it is passed on to the liver,” he said.

Once in the liver, it is converted to a derivative of fructose. It’s important to determine if alternative sweeteners are providing a healthy alternative to table sugar since people with diabetes and other metabolic disorders may be relying on them as “sugar free” products.

Gut bacteria do a good job of clearing sorbitol when it is present at modest levels, such as those found in fruit. But problems arise when sorbitol quantities become higher than what gut bacteria can degrade. This can occur when excessive amounts of glucose are consumed in the diet, which lead to high levels of glucose-derived sorbitol, or when dietary sorbitol itself is too high.

The more glucose and sorbitol consumed, then, even if someone has the friendly bacteria that clears it, those gut microbes may be overwhelmed with the task.

Avoiding both sugar and alternative sweeteners is increasingly complicated, as many foods are packed with multiple varieties of all the above. Patti was bemused to discover his own favorite protein bar was chock full of sorbitol.

The lab will need to do more research to understand the specific mechanisms for how bacteria clears sorbitol, but the basic idea that these sugar alcohols, called polyols, are harmlessly expelled, may not hold true.

“We do absolutely see that sorbitol given to animals ends up in tissues all over the body,” he said.

Bottom line: it’s becoming more apparent that “there is no free lunch” when trying to find sugar alternatives, with many roads leading to liver dysfunction.


Jackstadt MM, Fowle-Grider R, Song MG, Ward MH, Barr M, Cho K, Palacios HH, Klein S, Shriver LP, Patti GJ. Intestine-derived sorbitol drives steatotic liver disease in the absence of gut bacteria. Sci Signal. 2025 Oct 28. DOI

https://10.1126/scisignal.adt3549

This work was supported by the National Institutes of Health, grants R35ES028365 (G.J.P.) and P30DK056341 (S.K.).


 

The transformation of adult heart transplantation in the United States and Western Europe



Stanford University Department of Cardiothoracic Surgery
Image of Paper on Adult Heart Txp in the US and Western Europe 

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Recent paper on "Adult Heart Transplantation in the USA and Western Europe: State of the Art Review,” published in European Heart Journal. 

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Credit: Stanford Department of Cardiothoracic Surgery





In nearly 60 years, heart transplantation has transformed from a daring vision to an established surgical procedure. Since the first adult heart transplant in the United States was performed at Stanford Hospital in 1968, the field has made significant strides. However, challenges remain, including a shortage of donor organs and socioeconomic disparities.

A recent review, led by researchers from the Stanford Department of Cardiothoracic Surgery in collaboration with Germany's Helios Hospital, examines the current state, challenges, and future directions of adult heart transplantation in its two highest-volume regions – the United States and Western Europe. While both areas have achieved remarkable success, they have embraced varying approaches in their transplantation systems, shaped by the cultural and political attitudes of the region.

"As a leader in the field, Stanford has a decades-long history of pioneering and advancing heart transplantation," said Carol Chen, MD, first author on the paper and Surgical Director of Adult Heart Transplantation at Stanford Health Care. "Our aim with the review was to provide clinicians around the world with insights into how other transplant systems operate and to encourage opportunities to learn from one another."

Structures and Policies in Transplant Organizations

Drawing on extensive literature review and studies over the past decades, Dr. Chen described how transplant management systems have evolved differently in the United States compared to many European nations. In particular, opt-in versus opt-out (presumed consent) donation frameworks stood out.

"Despite being an opt-in organ donation system, the United States has one of the highest donation rates around the world," said Dr. Chen. In the United States, both organ donation and transplant rates have steadily increased since 2015. Over the last decade, the overall heart transplant rate has increased more than 80%, driven by national allocation policy changes and more aggressive organ recovery practices. She noted that, in contrast, European nations have demonstrated minimal growth in transplant volumes during this same time frame.

In Europe, organ donation policies and practices vary significantly, and many countries have adopted an organ donation opt-out system. International organizations like Eurotransplant and Scandiatransplant play crucial roles in optimizing organ sharing across borders and increasing donor organ availability. Despite these frameworks, many European countries continue to struggle with low donation rates due to limited resources, public awareness, and ethical concerns surrounding opt-out systems.

"Compared to the single centralized organ allocation system employed in the United States, the burden of navigating the multiple layers of regional, national, and international donation and allocation policies may play a role in the lower number of transplants performed in Europe versus the United States," said Dr. Chen.

Addressing the Donor Pool Shortage Through Innovation

With thousands of patients waiting for a heart transplant around the world, the demand for organs far exceeds the available supply. The authors highlight how each region has taken varied approaches to this issue, including the use of mechanical circulatory support systems, marginal donors, and hearts from donation after circulatory death (DCD) patients.

Recently, researchers have also explored using bioengineered hearts, mechanical devices, and xenotransplantation to address the donor organ shortage. All have had varying levels of success, but none have yet been able to replace a donated heart.

Technology is also transforming organ transport, helping to overcome the logistical challenges of time and distance. “By utilizing new technology, we can safely bridge greater distances between donor and recipient. This capability expands the donor pool and gives more of our patients at Stanford a chance at a new life," said William Hiesinger, MD, Associate Professor of Cardiothoracic Surgery and Section Chief of Heart & Lung Transplantation and Mechanical Circulatory Support at Stanford.

In 2022, Stanford cardiothoracic surgeons developed and applied a method to transplant a beating heart, supported by an organ perfusion system machine, into the recipient. Many transplant programs around the country have now adopted this technique. The use of these organ preservation systems has the potential to allow worldwide sharing of organs, increasing the possibility of finding a match for recipients.

"Overcoming challenges such as donor shortages, geographic barriers, and regulatory inconsistencies will require a collective effort to ensure equitable access to life-saving therapies for all patients now and in the future," said Dr. Chen.

The paper, “Adult Heart Transplantation in the USA and Western Europe: State of the Art Review,” was published in the European Heart Journal in November 2025. 

View article.

 

‘You don’t need a big brain to fly’ and other lessons from the first flying reptiles



Virginia Tech
Michelle Stocker (at center) reviews fossil scans with students. 

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Michelle Stocker (at center) reviews fossil scans with students.

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Credit: Photo by Spencer Coppage for Virginia Tech.





Flight evolved only three times among vertebrates: in bats, birds, and the extinct flying reptile called pterosaurs.

Of these, pterosaurs were the first to master flight, more than 215 million years ago — long before the appearance of the earliest birds.

For decades, scientists puzzled over how pterosaurs evolved the ability to fly as well as the anatomical changes that made flight possible.

But understanding how flight arose was hampered by a lack of well-preserved pterosaur fossils. To work around this gap, paleontologists have been investigating a close relative of pterosaurs — a flightless two-legged animal group called lagerpetids that lived alongside the earliest dinosaurs in several regions of the world.

Virginia Tech geoscientists were part of an international research team that used CT scanners to digitize fossilized and modern skulls representing a wide array of early land reptiles — including pterosaurs, lagerpetids, and dinosaurs as well as today’s crocodiles and birds.

“Technology like CT scanning gives us ways to ask and address questions that just weren’t possible for so long,” said Virginia Tech geobiologist Michelle Stocker, who co-authored the study published recently in Current Biology with fellow geobiologist Sterling Nesbitt.

By analyzing the high-resolution 3D reconstructions of the brain cavities inside the skulls, the team was able to map the stages of changes in brain shape and size before and after the evolution of flight.

For instance, the brains of lagerpetids displayed features linked to improved vision, such as an enlarged optic lobe, which allowed them to navigate their environments and prey on small organisms. This adaptation may have helped their pterosaur relatives take to the skies more than 200 million years ago.

However, the study also shows that pterosaurs never reached the degree of brain enlargement observed in modern birds, whose sophisticated brain structures were inherited from their dinosaur ancestors.

“Interestingly, we found that pterosaurs had relatively small brains, comparable in size to those of non-flying dinosaurs and much smaller than that of birds,” Nesbitt said.

In other words, you don’t need a big brain to fly.

Original study: DOI:10.1016/j.cub.2025.10.086