Wednesday, January 15, 2025

 

Evaluation of influence of offshore wind farm noise on fishes and dolphins




KeAi Communications Co., Ltd.

Figure 

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(a) An illustration of the biodiversity in the wind farm region, with at least three marine taxa that can both produce and sense sounds: snapping shrimp, fishes, and Indo-Pacific humpback dolphins. (b) The predicted impact zone of pile driving noise for fish, where the SELss values are higher than the fish safety threshold of 181.74 dB. The predicted (c) temporary and (d) permanent threshold shift zones of pile driving noise for the Indo-pacific humpback dolphin, where the SELw_cum values are higher than the safety threshold of 170 and 185 dB respectively.

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Credit: Zhongchang Song




The use of fossil fuels has affected both land and ocean environments, leading to a growing need for clean and affordable energy sources to reduce greenhouse gas emissions. In particular, offshore wind energy as a form of blue energy is rapidly developing in recent decades. However, the boom of offshore wind farms has raised concerns about the impact of the radiating underwater noise on marine inhabitants during both construction and operation, especially those sound-dependent organisms.

Against this backdrop, a team of researchers led by Professors Zhongchang Song and Yu Zhang from Xiamen University collaborated Senior Scientist Honghui Huang and his team from the South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, to conduct field measurements of the underwater noise of an offshore wind farm in the Pearl River Estuary. They developed an impact-zone estimating model to evaluate the impact zone of the wind farm noise for the fishes and dolphins in the Pearl River Estuary.

Notably, acoustic analysis results showed that the low-frequency operational noise (below 2.5kHz) of wind turbine was significantly lower in the intensity than the broadband pulsed pile driving noise produced during construction, which had a mean zero-to-peak sound pressure level up to 195.1 dB (re 1 μPa) (n = 238) at 30 m from the construction site.

“The Pearl River Estuary is home to the largest group of Indo-Pacific humpback dolphins in the world and our acoustic recordings showed a high diversity of biological acoustics in the wind farm, including fishes, snapping shrimp, finless porpoises and the Indo-pacific humpback dolphins,”  shares Song, who serves as the lead author of the study published in the KeAi journal Water Biology and Security. “The intense pile driving noise during construction of wind farm surpassed the hearing thresholds of the fishes and Indo-pacific humpback dolphin by far, and will inevitably induce negative impacts on these animals.”

To assess the impact scopes of the pile driving noise on marine animals, the researchers developed an impact-zone estimating model base on the cumulative sound exposure level. By referring to established noise exposure metrics, the impact zone of pile driving noise for fishes was estimated to be 12.8m. As for the Indo-Pacific humpback dolphins, the permanent (PTS) and temporary threshold shift (TTS) zones were predicted to be 32.4 m and 580.9 m, respectively.

“Our approach and findings enable us to better protect the local marine life from the effects of pile driving noise radiation, and guide the development of management policies during the construction of offshore wind farm,” adds Song.

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Contact the author: Zhongchang Song, Key Laboratory of Underwater Acoustic Communication and Marine Information Technology (Ministry of Education), College of Ocean and Earth Sciences, Xiamen University, Xiamen, China, songzc@xmu.edu.cn

The publisher KeAi was established by Elsevier and China Science Publishing & Media Ltd to unfold quality research globally. In 2013, our focus shifted to open access publishing. We now proudly publish more than 200 world-class, open access, English language journals, spanning all scientific disciplines. Many of these are titles we publish in partnership with prestigious societies and academic institutions, such as the National Natural Science Foundation of China (NSFC).

 

 

Bird flu is mutating, but antivirals still work



Researchers at Texas Biomed identified nine mutations in a bird flu strain from a person in Texas. Bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: approved antivirals are still effective.




Texas Biomedical Research Institute

Bird flu research at Texas Biomed 

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Professor Luis Martinez-Sobrido, Ph.D., (left) and Staff Scientist Ahmed Mostafa Elsayed, Ph.D., (right) review test results for the presence of bird flu while wearing protective equipment required for biosafety level-3 laboratories.

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Credit: Texas Biomed




SAN ANTONIO (Jan. 15, 2025) -- One of the earliest strains of bird flu isolated from a human in Texas shows a unique constellation of mutations that enable it to more easily replicate in human cells and cause more severe disease in mice compared to a strain found in dairy cattle, researchers from Texas Biomedical Research Institute (Texas Biomed) report in Emerging Microbes & Infections.

The finding highlights a key concern about the H5N1 strains of bird flu currently circulating in the U.S.: the speed at which the virus can mutate when introduced to a new host.

Naturally found in wild birds and lethal in chickens, H5N1 has spread to a wide variety of mammals and began infecting dairy cows for the first time in spring 2024. As of early 2025, the outbreak had spread through herds across multiple states in the U.S. and infected dozens of people, mostly farm workers. So far, most people infected experience mild illness and eye inflammation and the virus is not spreading between people. The first H5N1 death in the U.S. was reported in January 2025 following exposure to infected chickens.

“The clock is ticking for the virus to evolve to more easily infect and potentially transmit from human to human, which would be a concern,” said Texas Biomed Professor Luis Martinez-Sobrido, Ph.D., whose lab specializes in influenza viruses and has been studying H5N1 since the outbreak began last year. The team has developed specialized tools and animal models to test prophylactic vaccines and therapeutic antivirals.

Human vs. bovine

In the recent study, they compared H5N1 strains isolated from a human patient and from dairy cattle in Texas.

“There are nine mutations in the human strain that were not present in the bovine strain, which suggests they occurred after human infection,” Dr. Martinez-Sobrido said.

In mouse studies, they found that compared to the bovine strain, the human strain replicated more efficiently, caused more severe disease and was found in much higher quantities in brain tissue. They also tested several FDA-approved antiviral medications to see if they were effective against both virus strains in cells.

“Fortunately, the mutations did not affect the susceptibility to FDA-approved antivirals,” said Staff Scientist Ahmed Mostafa Elsayed, Ph.D., first author of the study.

Antivirals will be a key line of defense should a pandemic occur before vaccines are widely available, Dr. Martinez-Sobrido said. This is especially true since humans have no preexisting immunity against H5N1 and seasonal flu vaccines appear to offer very limited protection, according to a separate study conducted in collaboration with Aitor Nogales, Ph.D., at the Center for Animal Health Research in Spain.

Next steps and recommendations

Texas Biomed is now exploring the human H5N1 mutations individually to determine which are responsible for increased pathogenicity and virulence. The team wants to figure out what allows H5N1 to infect such a wide range of mammal species; why H5N1 causes mild disease in cows but is lethal in cats; and why infections via cows are less harmful to people than infections from chickens.

In a third paper, Dr. Elsayed and collaborators analyzed the history of H5N1 in dairy cattle for the journal mBio and called for a One Health approach to protect both animals and people.

“A key priority will be to eradicate bird flu from dairy cows to minimize risk of mutations and transmission to people and other species,” Dr. Elsayed said. “Steps that can be taken now include thorough decontamination of milking equipment and more stringent quarantine requirements, which will help eliminate the virus more quickly in cows.”

Papers:

Mostafa, A., Barre, R. S., Allué-Guardia, A., Escobedo, R. A., Shivanna, V., Rothan, H., … Martinez-Sobrido, L. (2025). Replication kinetics, pathogenicity and virus-induced cellular responses of cattle-origin influenza A(H5N1) isolates from Texas, United States. Emerging Microbes & Infections14(1). https://doi.org/10.1080/22221751.2024.2447614

Mostafa A, Naguib MM, Nogales A, Barre RS, Stewart JP, García-Sastre A, Martinez-Sobrido L. 2024. Avian influenza A (H5N1) virus in dairy cattle: origin, evolution, and cross-species transmission. mBio 15:e02542-24. https://doi.org/10.1128/mbio.02542-24

Sanz-Muñoz I, Sánchez-Martínez J, Rodríguez-Crespo C, Concha-Santos CS, Hernández M, Rojo-Rello S, Domínguez-Gil M, Mostafa A, Martinez-Sobrido L, Eiros JM, Nogales A.0.Are we serologically prepared against an avian influenza pandemic and could seasonal flu vaccines help us?. mBio0:e03721-24. https://doi.org/10.1128/mbio.03721-24

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About Texas Biomed

Texas Biomed is a nonprofit research institute dedicated to protecting the global community from infectious diseases. Through basic research, preclinical testing and innovative partnerships, we accelerate diagnostics, therapies and vaccines for the world’s deadliest pathogens. Our San Antonio campus hosts high containment laboratories and the Southwest National Primate Research Center. Our scientists collaborate with industry and researchers globally, and have helped deliver the first COVID-19 vaccine, the first Ebola treatment and first Hepatitis C therapy.

 

How crickets co-exist with hostile ant hosts




Nagoya University
How crickets co-exist with hostile ant hosts 

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How crickets co-exist with hostile ant hosts using dodging and distancing behaviors.

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Credit: Issey Takahashi



Researchers at Nagoya University in Japan have discovered sophisticated behavioral strategies that enable parasitic crickets to survive within ant colonies. Led by Ryoya Tanaka, the team documented how these insects successfully navigate life among potentially lethal hosts through precise evasion tactics. Their findings, published in Communications Biology, reveal remarkable adaptations that allow these cricket species to thrive in a hostile environment. 

Animals that live in ant colonies, known as “ant guests”, exploit their hosts’ resources.  However, this behavior carries a significant risk because ants ruthlessly exterminate intruders upon detection.   

Myrmecophilus ant crickets employ specialized escape behaviors to avoid ant attacks. Tanaka and colleagues studied this behavior in Myrmecophilus tetramorii, a "brood parasite" that sustains itself within host colonies by consuming dead insects and ant larvae. The researchers studied the behaviors that allow crickets to escape from their hosts.

They found that most behaviors could be classified into two types: “distancing,” where the crickets move directly away from the ants and “dodging,” where the crickets fled from the ants in a circular movement that positioned them behind the ants to avoid their mandibles. They noticed that when the cricket initiated dodging behavior, it stayed farther from its host and moved at a slower pace than during distancing. 

The researchers concluded that crickets employ dodging behavior to methodically evade perceived threats under low-risk conditions, while they utilize distancing behavior as a rapid defensive response when facing imminent attack.

“While distancing behaviour can quickly get crickets away from the approaching ant, such quick movements may alert surrounding potential enemies to the crickets’ presence, triggering an aggressive chase by another ant. Ant crickets benefit from a slow and precise reaction to dodging, which reduces the probability of being attacked by ants,” Tanaka explained. “In most cases, the ant cricket used dodging to escape from its host ants. Distancing incidents were comparatively rare.” 

When they observed the behavior of crickets that were already integrated into the host ant colony, the researchers found that the crickets did not move uniformly around the colony but tended to stay close to certain locations, such as those with accumulated debris, areas with wet paper, and corners.  

“Dodging behaviour is advantageous for staying in attractive areas while avoiding ants,” Tanaka explained. “The unique trait of dodging behaviour might be a way of effectively staying in a safe location while avoiding a succession of incoming ants, allowing them to reduce the risk of being attacked.”  

By staying in advantageous locations and carefully employing the two strategies, crickets can survive in the hostile environment of the host colony. Tanaka hopes that his research will open people’s eyes to the fascinating world of insects. “I often stroll around the Nagoya University campus to see insects. I still remember when I saw an ant cricket skillfully evading ants despite being surrounded by them,” he said. “From that moment on, I was utterly enthralled by this behavior.”