Wednesday, March 05, 2025

 

Highly radioactive nuclear waste – how to keep it from oblivion



Linköping University
Thomas Keating 

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Postdoctoral fellow Thomas Keating at Tema T – Technology and Social Change at Linköping University, Sweden.

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Credit: Per Wistbo Nibell




Sweden’s radioactive nuclear waste will be stored in a sealed bedrock repository for 100,000 years. It will be hazardous for a very long time. So how can we ensure that humanity does not forget that it is there? Researchers at Linköping University, Sweden, have come up with a proposal for how to keep the memory alive over generations.

“We’re trying to do something that no one has ever done before. The person who eventually reads this might not even be human, but perhaps a kind of AI or something else,” says postdoctoral fellow Thomas Keating, who led the research project together with Professor Anna Storm at Tema T – Technology and Social Change at LiU.

What he is referring to is a 42-page, oblong document with a yellow cover, called the Key Information File (KIF). It contains the most important information that a future reader may need about the planned final repository next to the Forsmark nuclear power plant in Sweden. It is divided into three parts: summary, critical information and instructions for the future.

The document was produced on behalf of the Swedish Nuclear Fuel and Waste Management Company (SKB). The idea is that it will keep the memory of the final repository alive. Although the repository is to be sealed and thus in theory inaccessible, accidental or intentional intrusion, technological failure or existential societal change cannot be ruled out. All of this makes it important not to forget what is buried there.

The researchers have tried to create a document enticing the reader to reread it and share it with others. They have used professional illustrators to make it aesthetically pleasing. While the text is easy to understand, there are mysterious characters on the cover. It is a coded message for the reader to try to solve. Through playfulness, the researchers want to create curiosity and enthusiasm. 

But language changes over time. So does the interpretation of images and symbols. The document therefore tasks future generations with updating the information and transferring it to new storage media if necessary. It also provides suggestions on how knowledge can be kept alive, for example by including it as a subject in school curricula or creating stories and other cultural expressions around it.

The researchers have named this method SHIRE (SHare, Imagine, REnew). It is an invitation to the reader to share the content and become actively involved in figuring out how it can be renewed so as not to be forgotten.

The Key Information File is the result of three years of work. It has been reviewed in scientific seminars and in workshops with representatives of clients, the public and industry organizations, nationally and internationally. Several countries, such as France and Switzerland, are working on similar documents for their final repositories.

The researchers propose an update of the document every ten years, but it is not clear who will be responsible for this in Sweden. Although SKB has financed the research project, they have clearly stated that they do not want formal responsibility but are willing to contribute in some form. Thomas Keating believes that one explanation for this is the long timeframe and that SKB is not meant to exist past the completion of the final repository. 

Very few people in the nuclear industry are working on the question of how to preserve the memory of nuclear waste. There are several examples of how when someone dies or retires and work on this issue is discontinued.

“Perhaps we need a whole new research area for this type of memory study. This could be something for the universities to develop in the future,” says Thomas Keating.

The idea now is that the document be kept at The Swedish National Archives. In addition, it has already been decided that it will be part of the major archiving project Memory of Mankind. It is an archive founded in Austria in 2012 which aims to preserve humanity’s collective knowledge for posterity on material that will last for thousands of years. 

“So it will be printed on ceramic tablets and placed in an old salt mine in a mountain in Austria,” says Thomas Keating.

The cover of the Key Information File.


SHIRE (SHare, Imagine, REnew) is an invitation to the reader to share the content and become actively involved in figuring out how it can be renewed so as not to be forgotten.


The Key Information File contains critical information on the final repository for Sweden's nuclear waste.

Credit

Per Wistbo Nibell














 

Generations ‘sync’ up in rural ‘glades’ to boost technology use for health



Nursing study pairs teens, older adults with smartwatches to test monitoring health in under-resourced communities




Florida Atlantic University

Monitoring Health in Under-resourced Communities 

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Lisa Ann Kirk Wiese, Ph.D., senior author, (seated, center) with members of the faith-based community team who worked with the students.

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Credit: Florida Atlantic University




Given the growing role of mobile technology in supporting older adults, it’s essential to implement initiatives that encourage its adoption among this population. However, older adults are often unfamiliar with mobile technology, especially those in rural areas with limited digital access or literacy.

To bridge this gap, researchers from Florida Atlantic University’s Christine E. Lynn College of Nursing, and collaborators, implemented a pilot study to test an intergenerational program involving high school students, older adults and local faith-based health educators in the “Glades,” a rural community nestled at the southern tip of Lake Okeechobee in South Central Florida.

Older residents in this tight-knit community share a strong desire to maintain healthy habits that support aging in place. However, their ability to track and monitor these habits using wireless fitness devices like Fitbits and smartwatches is hindered by the area’s limited resources and the difficulties many residents have with mobile technology literacy.

The impetus for the community-driven study in this under-resourced area was for older residents (ages 53 to 84) to embrace technology and gain greater acceptance and use of health-tracking devices as well as assessing everyday brain health behaviors.

For the study, an ecological momentary assessment (EMA) was used to deliver health-related survey questions via a smartwatch four times a day asking questions like “In the past two hours, how much social contact have you had?,” “How physically active have you been?” and “How mentally engaged have you been?” In addition, paper-and-pencil assessments were used to screen for cognition, health literacy and technology competence. Researchers explored the relationships between these screening measures and the usage of the smartwatch.

Results, published in the journal Educational Gerontology, showed that 91% of older adults engaged with the smartwatch prompts, with an overall response rate of 77.8%. Interestingly, response rates were not influenced by factors such as health literacy, technology self-efficacy, self-reported cognitive status, education, age or rural living. Additionally, social contact was found to be positively associated with physical activity, mental engagement and the perception of having a “sharp mind,” highlighting the importance of social engagement for brain health. The training process and the use of smartwatches proved effective for participants with varying levels of technology and health literacy.

“Our study created a win-win situation for everyone involved: older adults gained new skills in using wearable technology to monitor their health, while high school students had the opportunity to learn processes for conducting meaningful research and develop valuable skills,” said Lisa Ann Kirk Wiese, Ph.D., senior author and an associate professor, Christine E. Lynn College of Nursing. “Faith-based health educators, trusted figures within their communities, were able to contribute to the well-being of those they serve, fostering a sense of empowerment and connection across generations.”

For the study, participants wore the smartwatch for at least two weeks and received a simultaneous ringtone and vibration for each prompt. High school students (ages 15-19) trained participants on how to wear the smartwatch and respond to prompts using step-by-step guides. They assisted with setup, including charging the watch and understanding prompt timings, and offered additional support during follow-up visits.

Before participants began using the smartwatches, faith-based health educators administered surveys, with high school students often present. Participants also completed a brief cognitive screening (Borson’s Mini-Cog©), health literacy assessment, and a sociodemographic survey during the initial screening.

Students expressed gratitude for the opportunity to participate in a research initiative, with many seeking further research-related positions or scholarships. They valued the chance to add this experience to their resumes. All participants agreed they would likely never have used a smartwatch without the students’ guidance. Participants with more years of education expressed that wearing the smartwatch was particularly enjoyable and they were curious about their progress. For those with less education, more hands-on training was needed. Both students and older adults appreciated the time spent together, with students gaining valuable skills like teaching technology, patience and empathy. They also felt a sense of responsibility and open-mindedness.

“High school students don’t just teach older adults about mobile health – they also gain invaluable skills and insights themselves,” said Wiese. “Through these meaningful interactions, students discover how technology can improve health monitoring and care, while being inspired to pursue careers in aging, health care and gerontechnology. These experiences not only prepare them for future careers but also foster a deep appreciation for the power of digital health in their own lives.”

Through community-based participatory research, the FAU nurse-led team has collaborated with gatekeepers and stakeholders across the past 10 years to increase care of older adults in this region.

Study co-authors are Catherine Luna, Department of Psychology, Washington State University; Diane Cook, Ph.D., Regents Professor and Huie-Rogers Chair Professor, School of Electrical Engineering and Computer Science, Washington State University; Bryan D. Minor, Ph.D., associate in research, School of Electrical Engineering and Computer Science, Washington State University; and Marueen Schmitter-Edgecombe, Ph.D., Regents Professor, H.L. Eastlick Distinguished Professor, Department of Psychology, Washington State University.  

This research was supported by the National Institute on Aging of the National Institutes of Health under award number R35 AG071451, and by the National Science Foundation under award number 1954372.

- FAU -

About Florida Atlantic University:
Florida Atlantic University, established in 1961, officially opened its doors in 1964 as the fifth public university in Florida. Today, Florida Atlantic serves more than 30,000 undergraduate and graduate students across six campuses located along the Southeast Florida coast. In recent years, the University has doubled its research expenditures and outpaced its peers in student achievement rates. Through the coexistence of access and excellence, Florida Atlantic embodies an innovative model where traditional achievement gaps vanish. Florida Atlantic is designated as a Hispanic-serving institution, ranked as a top public university by U.S. News & World Report, and holds the designation of “R1: Very High Research Spending and Doctorate Production” by the Carnegie Classification of Institutions of Higher Education. Florida Atlantic shares this status with less than 5% of the nearly 4,000 universities in the United States. For more information, visit www.fau.edu.

 

Toxic environmental pollutants linked to faster aging and health risks in US adults



“Environmental chemical exposures represent a key modifiable risk factor impacting human health and longevity, and our findings provide evidence for associations between several environmental exposures and epigenetic aging in a large sample..."



Impact Journals LLC

Exposome-wide association study of environmental chemical exposures and epigenetic aging in the national health and nutrition examination survey 

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Figure 3. Volcano plots displaying the expected change in GrimAge acceleration for a 1 SD increase in log2-transformed exposure on the X-axis, and -log10 p-values on the Y-axis from the sensitivity models adjusting for cotinine exposure. Color corresponds to the broad category of exposure. Volcano plots for remaining epigenetic clocks are presented in Supplementary Figure 4.

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Credit: Copyright: © 2025 Khodasevich et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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BUFFALO, NY — March 5, 2025 — A new research paper was published in Aging (Aging-US) on February 11, 2025, Volume 17, Issue 2, titled “Exposome-wide association study of environmental chemical exposures and epigenetic aging in the national health and nutrition examination survey.”

First author Dennis Khodasevich and corresponding author Andres Cardenas from Stanford University, and colleagues from other U.S. institutions, studied how exposure to harmful chemicals in the environment affects aging. Using data from the National Health and Nutrition Examination Survey (NHANES), they discovered that cadmium, lead, and cotinine are linked to faster biological aging, a process that can increase the risk of age-related diseases.

The study analyzed data from 2,346 U.S. adults aged 50 to 84 who participated in a national health survey. Researchers tested their blood and urine for 64 different chemicals, including metals, pesticides, and industrial pollutants. They assessed how these exposures influenced eight different epigenetic aging markers—biological clocks that measure how fast a person’s body is aging at the DNA level.

“We harnessed data from the National Health and Nutrition Examination Survey 1999-2000 and 2001-2002 cycles to examine exposome-wide associations between environmental exposures and epigenetic aging.”

The strongest effects were linked to cadmium, a toxic metal found in cigarette smoke and some foods. People with higher levels of cadmium in their blood showed signs of accelerated aging. Higher levels of cotinine, a chemical related to tobacco exposure, were also linked to increased biological age, reinforcing the harmful effects of smoking. Additionally, lead exposure, a heavy metal found in old paint and contaminated water, was also associated with faster aging.

The researchers also found that some pollutants, including a type of PCB (PCB118) and a type of dioxin (HpCDD), were linked to slower biological aging. However, it is unclear if this fact is beneficial, as past research shows that slower aging in some cases can still be linked to health risks.

This study is one of the largest to investigate how pollution affects the aging process. Unlike previous research that focused on only a few chemicals, it examined a wide range of pollutants in a diverse group of people. The findings suggest that everyday exposure to toxic substances can speed up aging at the cellular level, increasing the risk of age-related diseases.

In summary, these findings raise concerns about how widespread environmental contaminants may accelerate aging and contribute to chronic diseases such as heart disease, cancer, and cognitive decline. Reducing exposure to toxic substances like cadmium and lead—found in cigarettes, polluted air, and contaminated food—could help slow biological aging and improve long-term health. These insights highlight the need for stronger environmental health policies to protect individuals from premature aging and disease.


Read the full paper: DOIhttps://doi.org/10.18632/aging.206201

Corresponding author: Andres Cardenas — andresca@stanford.edu

Keywords: aging, epigenetic aging, environmental exposures, exposome, epigenetics

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About Aging:

The journal Aging aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Aging is indexed by PubMed/Medline (abbreviated as “Aging (Albany NY)”), PubMed CentralWeb of Science: Science Citation Index Expanded (abbreviated as “Aging‐US” and listed in the Cell Biology and Geriatrics & Gerontology categories), Scopus (abbreviated as “Aging” and listed in the Cell Biology and Aging categories), Biological Abstracts, BIOSIS Previews, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science).

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