Wednesday, January 15, 2025

 

A ‘smoke-free generation’ in Canada? New analysis says it would result in vast health gains, healthcare cost savings




University of Ottawa
A ‘smoke-free generation’ in Canada? New analysis says it would result in vast health gains, healthcare cost savings 

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Dr. Doug Coyle of the University of Ottawa suggests that if the Canadian government were to implement a “smoke-free generation” policy there would be massive health benefits. His study estimates that the policy would result in $2.3 billion less in health care costs and lead to 476,814 more quality-adjusted life years for Canadians over a 50-year timespan.

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Credit: Faculty of Medicine, University of Ottawa




Smoking stubbornly remains a leading cause of disease, disability and death in Canada, even as prevalence rates have fallen significantly over the last 50 years. So what new smoking cessation initiative can save lives and billions of dollars in health-care costs?

A highly compelling analysis by a uOttawa Faculty of Medicine health economist explores the long-term impacts of one bold smoking restriction proposal: a lifetime ban on tobacco products to individuals born after a specific date.

This “smoke-free generation” concept is aimed at forging a generation of individuals who would never be able to legally purchase tobacco or nicotine vaping products. It proposes that preventing young people from taking up smoking is key since roughly 80 percent of people take up smoking by age 18, and nearly all smokers start by age 26. It’s a policy measure that was seriously debated in New Zealand and has been recommended by smoking cessation experts in Canada.

Dr. Doug Coyle suggests that if the Canadian government were to implement a “smoke-free generation” policy there would be massive health benefits. His study estimates that the policy would result in $2.3 billion less in health care costs and lead to 476,814 more quality-adjusted life years for Canadians over a 50-year timespan.

The analysis assumed a perpetual ban on cigarette sales to anyone born after 2009 if imposed on Jan. 1, 2025.

The research forecasting the long-term impacts of a SFG policy was featured today in the January edition of Health Promotion and Chronic Disease Prevention in Canadaa publication of the Public Health Agency of Canada. 

One of the peer-reviewed journal's reviewers described Dr. Coyle’s analysis as a “very important piece of work which could influence policy.”

An expert at researching health economics and applying analyses to health policy, Dr. Coyle says the study’s “biggest finding is that introducing a SFG policy would lead to substantive health gains with significant health care cost savings.”

“Current legislation is ineffective as most long-term smokers initiate smoking prior to the legal age for smoking.  Thus, a SFG policy avoids the vast health losses occurring due to uptake of smoking earlier than legally allowed,” he says.

The published analysis took an existing model relating to smoking cessation and augmented it to assess the impacts of an SFG policy on quality-adjusted life years (QALYs), life expectancy, health care costs, smoking-related taxes, and Canadian tobacco industry gross domestic product. The policy’s overall impact for the entire Canadian population was assessed for time periods up to 90 years.

While the study found that there would be significant health care cost saving and more quality-adjusted life years for Canadians, it also found the policy would also result in $7.4 billion less in smoking-related taxes and a $3.1 billion reduction in tobacco industry GDP. However, the study suggests that the combined value of health benefits gained and health care costs averted would surpass the hit of lower tax revenues and reduced GDP.

“Although health care cost savings are lower than the combination of lost tax revenues and the decline in the GDP from the Canadian tobacco industry, the value of the health benefits realized outweigh the negative offsets,” the study concludes.

Dr. Coyle says that since taxes on tobacco smoking are regressive and impact poorer populations more proportionally than wealthier ones, the government could replace the lost tax with a “more progressive tax substitute" that "would be more fair and equitable.” 

Dr. Coyle’s decades of work have influenced the practice and methods of health economics and directly influenced policy in Canada and the UK. He’s a Professor Emeritus of the uOttawa Faculty of Medicine’s School of Epidemiology and Public Health (SEPH). He served as SEPH’s interim director from 2016-18 and was previously director of the graduate program in epidemiology.

 

 

Clouds have a surprising effect on surface warming, McGill climate researchers find



McGill University




McGill University researchers have discovered that changes in clouds are slightly mitigating global warming. While greenhouse gases continue to cause temperatures to rise, a reduction in low-cloud cover over land has brought about a modest reduction of the amount of heat being trapped close to ground level.

"We started this research to observationally verify the increase of greenhouse effect of the Earth atmosphere," said Yi Huang, Associate Professor in McGill’s Department of Atmospheric and Oceanic Sciences who conceived a recent study published in Nature, "We indeed verified that, although to our surprise we also found an offsetting effect due to changes in clouds."

“Without these cloud changes, the surface would warm even faster,” said Lei Liu, graduate student in McGill's Department of Atmospheric and Oceanic Sciences and the first author of this study. "This work offers observational truth about how clouds affect warming, which can be used to improve climate models and guide environmental policies,” said Liu.

To discover this surprising effect, the team used the measurements of a key radiative instrument, the Atmospheric Emitted Radiance Interferometer (AERI), along with satellite data, climate models and a technique called "optimal spectral fingerprinting" co-designed by Yi Huang and Lei Liu to isolate the effects of clouds from other atmospheric processes.

The researchers focused on longwave radiation, the heat energy Earth emits back into the atmosphere. Usually, clouds trap some of this heat and send it back to the ground. But as the climate warms, there are fewer low clouds in some areas, which means less heat is returned to the surface.

McGill’s Atmospheric and Oceanic Department, which operates three AERI instruments in Montreal, looks to continue using their critical data for understanding regional climate dynamics and enhancing climate modelling, the researchers said.

 

“Our research emphasizes the value of precise, long-term climate observations,” said John Gyakum, co-author and Professor in the Department of Atmospheric and Oceanic Sciences“This is essential for understanding Earth’s response to global warming and making informed decisions for future generations.”

The researchers cautioned that their discovery does not throw doubt on global warming.

“It’s like having a thermostat that adjusts itself a little,” the researchers explained. “But even with this adjustment, the room is still heating up.”

About the study

Clouds reduce downwelling longwave radiation in a warming climate ” by Lei Liu, Yi Huang, and John R. Gyakum was published in Nature.

This research was funded by grants of the Natural Sciences and Engineering Research Council of Canada (RGPIN-2019-04511) and the Environment and Climate Change Canada (EDF-CA-2021i022) awarded to Yi Huang as Principal Investigator.

 

Pesticide impacts on bees more complex than expected



New study shows effects 'akin to ageing and cancer'




Queen Mary University of London

Bumble Bee 

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Bumble Bee

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Credit: Image credit: Andres Arce




A new study shows distinct effects of neonicotinoid pesticide exposure in different bumble bee body parts, explaining why pesticides have diverse harmful effects and highlighting the need for more sensitive safety testing.

Researchers at Queen Mary University of London have discovered that the neonicotinoid pesticide clothianidin disrupts different parts of bumble bee bodies in strikingly different ways. The researchers’ new study shows that the impacts of pesticides are far from uniform, affecting the brain, legs, and kidney-like tissues in different manners that undermine each tissue’s essential functions. 

Distinct impacts on different tissues 
By exposing bumble bees to a field-realistic dose of clothianidin, the scientists found dramatic differences in gene activity across body tissues – 82% of gene activity changes were tissue-specific.

“Each tissue we examined was severely affected by the pesticide,” explains Professor Yannick Wurm. “Seeing impacts of pesticide exposure across the body helps to explain the multi-faceted problems that exposed bees have, from impaired movement to reduced learning ability and compromised immunity.” 

Neonicotinoid pesticides such as clothianidin are widely used to protect crops from pests. Yet, past research has shown that even low doses can threaten the survival of beneficial insects. In this study, the researchers applied high-resolution molecular diagnostics – commonly used in biomedicine but rarely for environmental questions – to pinpoint the specific molecular pathways disrupted by pesticide exposure. For instance, while brain genes involved in ion transport were affected, the hind femur (crucial for movement) showed changes in muscle-specific genes, and the detoxification gene activities of Malpighian tubules (a functional equivalent of kidneys) decreased.

“The findings suggest that traditional pesticide risk assessments, which often overlook tissue-specific damage, do not fully capture the sub-lethal impacts on pollinators,” says Dr Federico López-Osorio, a co-author of the study.

Severe tissue-specific consequences prompt call to action

The researchers emphasise that these changes, akin to patterns seen in ageing and cancer, indicate a profound threat to bee health—affecting every tissue in damaging ways.

“We apply pesticides without fully understanding their effects on beneficial insect pollinators,” said lead author Dr Alicja Witwicka. “Our findings show that every tissue is compromised in ways that undermine its vital role, which is why the effects are so devastating and widespread. This research is a call to action to rethink how we assess, regulate and apply pesticides, not only to protect pollinators but the ecosystems that depend on them.”

This study highlights an urgent need to reevaluate pesticide safety practices to prevent further harm to natural pollinators—species essential for producing the many fruits and nuts we eat and for maintaining biodiversity. It comes at a time when citizens and governments worldwide are increasingly concerned about biodiversity loss, setting ambitious targets for reversing declines and restoring ecosystem health.


Notes to Editors:
For more information, please contact: Press Office, Queen Mary University of London Email: press@qmul.ac.uk

The paper, “A neonicotinoid pesticide causes tissue-specific gene expression changes in bumble bees,” is published in Science of the Total Environment and is available online: https://doi.org/10.1016/j.scitotenv.2024.178262
This research was performed at QMUL’s Evolutionary Genomics and Bioinformatics lab (https://wurmlab.com). It was funded by the Natural Environment Research Council, the European Commission (H2020), and the Biotechnology and Biological Sciences Research Council.
 

 

Biorefinery innovation: Transforming waste into high-value products




Eurasia Academic Publishing Group




A new study from the Universidade de Santiago de Compostela showcases a cutting-edge biorefinery capable of converting sewage sludge and food waste into valuable volatile fatty acids (VFAs).

Published in Environmental Science and Ecotechnology, the research evaluates the environmental impact of this biorefinery, located in Galicia, Spain, which produces commercial-grade VFAs like acetic, propionic, and butyric acids.

The study highlights the biorefinery's dual benefits: efficient waste management and reduced dependency on fossil fuels. Using pilot-scale data, the researchers demonstrated the scalability of this innovative technology, with food waste showing the best environmental performance per unit of product and sewage sludge excelling at handling large waste volumes.

Key factors influencing environmental performance include transportation and chemical use. Sodium hydroxide, essential for pH control, contributed up to 80% of chemical-related impacts. Additionally, transportation accounted for a significant share of the carbon footprint. The study recommends strategies such as optimizing facility locations and replacing sodium hydroxide with alternatives like magnesium hydroxide, which could cut impacts by 53% and 29%, respectively.

The biorefinery's carbon footprint—5.5 to 8.6 kg CO₂ per kilogram of acetic acid—is on par with other bio-based technologies. However, further improvements in purification are needed to fully compete with petrochemical processes.

This study underscores biorefineries' potential to revolutionize waste management, reduce environmental impacts, and promote a circular economy, marking a significant step toward sustainable production systems.

 

Breakthrough bioprocess turns CO2 and electricity into high-protein food




Eurasia Academic Publishing Group




A pioneering study published in Environmental Science and Ecotechnology has unveiled a novel bioprocess that transforms carbon dioxide (CO2) and electricity into single-cell protein (SCP), a sustainable and nutrient-rich food source. Developed by researchers from Xi’an Jiaotong University and the Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, this innovative system combines anaerobic and aerobic microbial processes to efficiently produce SCP using acetate as a key intermediate.

 

The system consists of two interconnected reactors: the first uses microbial electrosynthesis (MES) to convert CO2 into acetate, while the second employs aerobic bacteria (*Alcaligenes*) to upgrade acetate into SCP. By recirculating the medium between the reactors, the team achieved a remarkable cell dry weight of 17.4 g/L, with a protein content of 74%—surpassing traditional protein sources like fish and soybean meal. The process also minimizes pH adjustment, reduces wastewater generation, and alleviates product inhibition, enhancing both sustainability and efficiency.

 

This breakthrough offers a promising solution to global food security and climate challenges by converting CO2 into valuable protein. The SCP produced is rich in essential amino acids, making it an excellent supplement for animal feed and a potential candidate for human nutrition.

 

As global food demand rises and climate change intensifies, this technology represents a significant step toward a circular carbon economy, turning greenhouse gases into nutritious food while reducing environmental impact. The study underscores the potential of biohybrid systems to revolutionize sustainable food production and address pressing environmental issues.