Saturday, November 22, 2025

 

Monsoon storms will bring heavier rains but become weaker





University of Reading




Climate change will make monsoon storms in South Asia wetter and weaker, with more storms pushing further inland across India. 

Scientists from the University of Reading used 13 climate models to understand how warming temperatures will affect monsoon low-pressure systems. These storms deliver more than half of all monsoon rainfall and nearly all extreme rainfall events across South Asia. 

The research, published in the Journal of Climate, found that storms will become about 10% weaker by the time global temperatures rise 3°C above pre-industrial levels. Despite becoming weaker, each storm will produce more rain – up to 28% more for the strongest storms. By the time temperatures reach 2°C of warming, average rainfall from each storm will increase by roughly 10%. 

Dr Kieran Hunt from the University of Reading and lead author, said: “How can weaker storms produce more rain? It sounds wrong, but the answer partly lies in changes to moisture patterns. Warming temperatures increase the difference in moisture levels between northern and southern India. Winds ahead of storms push this extra moisture into the rainfall zone, making storms wetter even though their winds are slower.” 

More storms and more flooding 

The study suggests the number of monsoon storms will increase as temperatures rise. Models show roughly 15% more storms when temperatures reach 2°C above pre-industrial levels, though the increase varies between 10% and 36% depending on specific atmospheric patterns. The findings also indicate the time storms spend over land after moving from the ocean will increase significantly between 1.5°C and 2°C of warming, meaning western parts of India will face growing flood risks as temperatures rise.  

Four possible future scenarios based on different patterns of atmospheric circulation and moisture were created by the researchers, with all scenarios agreeing that more storms will also likely affect regions including Sri Lanka and Bangladesh.  

Professor Andy Turner, co-author, said: “We found four different pathways the monsoon could take as the world warms, but the message is the same across all of them. Wetter, more frequent storms will reach areas that rarely see them today. One scenario showed storms could increase by 36% if wind patterns change to bring more disturbances from Southeast Asia into the Bay of Bengal. Whichever path we follow, western India needs to prepare for more flooding." 

 

Toward a cervical cancer–free future: Cancer Biology & Medicine highlights science, policy, and equity


China Anti-Cancer Association
Eliminating Cervical Cancer: A Global Health Imperative for Women 

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Eliminating Cervical Cancer: A Global Health Imperative for Women

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Credit: Cancer Biology & Medicine




Cervical cancer will be the first human cancer eliminated through coordinated global action. A new special issue of Cancer Biology & Medicine brings together leading experts from around the world to examine progress, challenges, and innovations in prevention, screening, and treatment. From policy frameworks and epidemiological insights to digital health tools and therapeutic vaccines, the collection provides a timely resource for accelerating the World Health Organization’s 2030 targets for cervical cancer elimination and advancing women's health equity worldwide.

Each year, more than 340,000 women die from cervical cancer, with the majority of deaths occurring in low- and middle-income countries. Despite being highly preventable through vaccination and early detection, the disease remains the fourth most common cancer among women. In 2020, the World Health Organization (WHO) launched the Global Strategy to Accelerate the Elimination of Cervical Cancer, setting ambitious “90-70-90” targets for vaccination, screening, and treatment by 2030. Yet vast inequities in health resources, infrastructure, and implementation capacity threaten progress. Addressing these challenges requires not only scientific advances but also strong policy alignment and international cooperation.

To mark the 30th anniversary of the Fourth World Conference on Women and the 2025 World Women's Summit in Beijing, Cancer Biology & Medicine has released a special issue (https://www.cancerbiomed.org/content/22/9) dedicated to eliminating cervical cancer. Guest-edited by Professor Youlin Qiao of the Chinese Academy of Medical Sciences & Peking Union Medical College, the issue highlights global disparities, China's contributions, and the collective scientific and policy innovations needed to accelerate progress. The issue reflects the journal's mission to bridge cutting-edge oncology research with public health priorities, particularly in women's health.

The special issue brings together ten contributions spanning global perspectives, policy analysis, epidemiology, digital innovation, economic evaluation, and novel therapeutics. Highlights include an Editorial from the International Agency for Research on Cancer (IARC/WHO) outlining global disparities and China's contributions; a Perspective exploring how policy modeling can guide resource-sensitive elimination strategies in low- and middle-income countries; and an Original Article analyzing cervical cancer burden and trends in China from 2000 to 2020 in comparison with four Asia-Pacific countries.

Other notable studies showcase technological and clinical advances, such as the first international evaluation of a bilingual digital colposcopy education tool (iDECO), which significantly improves diagnostic accuracy, and the development of a therapeutic multi-epitope protein vaccine targeting HPV16 that demonstrates strong tumor regression in preclinical models.

Beyond these examples, the issue also features research on HPV vaccination willingness, innovative triage algorithms in rural China, intelligent digital platforms for population-based screening, and the economic impact of government-organized programs. Together, these articles provide a comprehensive view of scientific, clinical, and policy innovations driving the global elimination of cervical cancer. The full collection is available online.

“Cervical cancer is the only malignancy we can realistically eliminate through vaccination, screening, and early treatment,” said Professor Youlin Qiao, Guest Editor of the issue. “This special issue demonstrates the collective knowledge and innovation needed to achieve that goal. By combining science, policy, and equity, we can ensure that no woman is left behind in the global drive to eliminate cervical cancer.”

The timing of this issue aligns with renewed global attention to women's health at the 2025 World Women's Summit. By providing evidence-based insights across epidemiology, technology, economics, and therapeutics, Cancer Biology & Medicine aims to inform international collaboration and inspire action. The elimination of cervical cancer is not only a public health objective but also a milestone for gender equity and global health justice.

As the world moves closer to this unprecedented achievement, this special issue offers both a progress report and a call to action: eliminating cervical cancer is possible within our lifetime—but only if the global community works together.

For more details and to access the special issue “Eliminating Cervical Cancer: A Global Health Imperative for Women”, visit Cancer Biology &Medicine online.

Eliminating cervical cancer: a global health imperative for women
DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0529

Progress toward cervical cancer elimination: global disparities and China's contributions
DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0428

Strengthening human papillomavirus vaccination programs through multi-country peer learning: lessons from the CHIC initiative
DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0388

Modeling cervical cancer elimination: a pathway to inform policy decisions
DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0387

Human papillomavirus vaccination willingness under resource inequities: momentary intervention effects of an educational video
DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0400

Cervical cancer burden and trends in China, 2000–2020: Asia-Pacific international comparisons and insights for elimination goals
DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0386

Accelerating the elimination of global cervical cancer through intelligent training for colposcopy
DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0403

Evaluation of the multiple HPV-based “screen and triage” algorithms in real-world settings of rural China
DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0384

Evaluation of an intelligent digital platform for population management in cervical cancer screening
DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0419

Impact of government-organized screening programs on the economic burden of cervical cancer across five disease courses: a multistage regression and mediation analysis
DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0418

A therapeutic multi-epitope protein vaccine targeting HPV16 E6 E7 elicits potent tumor regression and cytotoxic immune responses
DOI: https://doi.org/10.20892/j.issn.2095-3941.2025.0370

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References

Journal

Cancer Biology & Medicine (CBM) is a peer-reviewed open-access journal sponsored by China Anti-cancer Association (CACA) and Tianjin Medical University Cancer Institute & Hospital. The journal monthly provides innovative and significant information on biological basis of cancer, cancer microenvironment, translational cancer research, and all aspects of clinical cancer research. The journal also publishes significant perspectives on indigenous cancer types in China. The journal is indexed in SCOPUS, MEDLINE and SCI (IF 8.4, 5-year IF 6.7), with all full texts freely visible to clinicians and researchers all over the world (http://www.ncbi.nlm.nih.gov/pmc/journals/2000/).

Video of Cancer Biology & Medicine [VIDEO] 

FEMICIDE U$A

Study reveals long-term associations of strangulation-related brain injury from intimate partner violence



In a federally funded study, Mass General Brigham investigators found self-reported vision problems and traumatic stress are experienced years after strangulation



Mass General Brigham





In a federally funded study, Mass General Brigham investigators found self-reported vision problems and traumatic stress are experienced years after strangulation 

Around the globe, nearly one in three women have experienced intimate partner violence (IPV). Among those women, 68% experience strangulation, which blocks air and blood flow to the brain and can cause brain injury. A new study by investigators from Mass General Brigham of 139 women found that strangulation-related brain injury was negatively associated with women’s health over time, including self-reported vision problems and traumatic stress. Their results are published in the Journal of Neurotrauma

“This study highlights potential long-term consequences of IPV-related strangulation and reinforces the importance of IPV prevention and providing treatment for women in need,” said corresponding author Eve Valera, PhD, an investigator in the Mass General Brigham Department of Psychiatry.  

As part of their federally funded study, the researchers recruited 139 mostly white women through flyers, online advertisements, and social media. Strangulation does not always result in brain injury, so carefully designating study participants into groups based on their experience was critical to understand the varying severity of symptoms. Three major subgroups were identified: strangulation; strangulation with altered consciousness—seeing stars, tunnel vision; and strangulation with full loss of consciousness. Participants in either altered or loss of consciousness categories were assumed to have acquired brain injuries. 

Among the participants, 64% reported a history of IPV-related strangulation; 30% reported strangulation-related alterations in consciousness; and 15% reported strangulation-related loss of consciousness. The researchers asked the three subgroups to self-report symptoms like dizziness, vision and hearing problems, poor concentration, anxiety, depression, and traumatic stress, between July 2020 and February 2023. On average, the last strangulation event participants experienced was 8.7 years prior to the participant’s interview.  

Vision problems and traumatic stress symptoms were greater in women who had experienced strangulation, with those that also experienced strangulation-related brain injury reporting more symptoms like stress, dizziness, and poor concentration. Strangulation-related alterations in consciousness were associated with escalated vision problems compared to strangulation alone, while full loss of consciousness was associated with escalated traumatic stress symptoms. The findings suggest self-reported neurobehavioral issues and traumatic stress may linger long after strangulation for all participants.  

“Strangulation is under-reported, and more work is needed to encourage disclosure, social interventions, and timely health care for those subjected to these violent events,” said Valera. 

 

Authorship: In addition to Valera, Mass General Brigham authors include Grant L. Iverson. Additional authors include Maria C. Xu, Aylin Tanriverdi. 

Disclosures: Iverson serves or has served as a scientific advisor for NanoDX®, Sway Operations, LLC, and Highmark, Inc. He has a clinical and consulting practice in forensic neuropsychology, including expert testimony, involving individuals who have sustained mild TBIs. He has received past research support or funding from several test publishing companies, including ImPACT Applications, Inc., CNS Vital Signs, and Psychological Assessment Resources (PAR, Inc.). He has received research funding as a principal investigator from the National Football League, and subcontract grant funding as a collaborator from the Harvard Integrated Program to Protect and Improve the Health of National Football League Players Association Members. He acknowledges philanthropic support from ImPACT Applications, Inc., the Mooney-Reed Charitable Foundation, and the Schoen Adams Research Institute at Spaulding Rehabilitation. None of the above entities were involved in the study design, analysis, interpretation, the writing of this abstract, or the decision to submit it for presentation. 
 
Funding: This work was supported by grant R01NS112694 (EMV) from the National Institute of Neurological Disorders and Stroke. 

Paper cited: Xu MC et al. “Title: History of Strangulation is Associated with Current Traumatic Stress, Self-Reported Vision Problems, and Other Neurobehavioral Symptoms in Women who have Experienced Intimate Partner Violence” Journal DOI: 10.1177/08977151251394000