Thursday, August 06, 2026

 

Osiris 41 brings together the histories of science and childhood studies





University of Chicago Press Journals









“What does science owe children, and how can the history of science contribute to repaying that debt?” This question motivates the 2026 volume of Osiris, entitled “Histories of Science and Childhoods.” Edited by Andrea Graus, Violeta Ruiz, and Elisabeth M. Yang, the volume features a collection of articles that examine the interrelation of two categories: childhood and science.

In the editors’ introduction, Graus, Ruiz, and Yang lay out their vision for the volume and foreground childhood studies as a useful theoretical framework with which to approach the history of science, medicine, and technology. They argue that history of science scholarship related to childhood has mainly privileged the West and Global North, and it has tended to take a “top-down” approach—that is, minimizing or erasing the voices of actual children. The editors point out that even the concept of “childhood” is not universal, as it relies on an ableist, colonial, and heteronormative conception of chronological time and age. Articles in the volume challenge these norms and assumptions by bringing together a creative array of source material and disciplinary perspectives.

Since the European Enlightenment, scientific knowledge about children has informed developments in technology, medicine, education, and social policy—developments that have profoundly impacted children’s lives and experiences. But rather than viewing science as unilaterally acting upon children and notions of childhood, the editors and contributors of Osiris 41 offer up a more dynamic way of understanding this relationship. Articles in the volume argue that “child and childhood create and act in and upon science and those who practice it.”  By treating children as “fully fledged historical actors,” the editors suggest, we can gain a new, more diverse perspective on the history of science that recognizes children’s influence and contributions.

The volume is comprised of three main sections. Firstly, a cluster of articles focuses on the notion of children’s agency, using varied sources to historicize and problematize this concept. Another section examines the technologies and politics of child health. A third section highlights the entangled relationship between childhood and science, exploring how ideas about childhood have shaped scientific thinking. To conclude the volume, a final essay unpacks the assertion that “every child is a scientist.”

Taken together, the contributions in Osiris 41 paint a picture of childhood as a “relational category”—a subjective concept defined in terms of what it is not. They ask readers to consider how and why we study science and how we choose objects of study. They suggest new ways to think about agency and its relationship to historical change. As the editors write: “Our hope is that this volume signifies the emergence of a new paradigm, one that conjoins the histories of science and childhood studies and promotes truly interdisciplinary—and in turn, transdisciplinary—work that bears not just the virtues of intellect but also that of moral beneficence, especially toward the marginalized and vulnerable.”


Founded in 1936 by George Sarton, and relaunched by the History of Science Society in 1985, Osiris is an annual thematic journal that highlights research on significant themes in the history of science.

Founded in 1924, the History of Science Society is the world’s largest society dedicated to understanding science, technology, medicine, and their interactions with society in historical context.

 

DNA innovation opens new frontiers in preventing disease before it begins



Compuscript Ltd
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Image Caption: Timeline of major discoveries and milestones in DNA-based disease prevention techniques, from the identification of DNA structure to recent advances in CRISPR-Cas gene editing, mRNA vaccine platforms, and epigenetic biomarker detection.

Image link: https://ars.els-cdn.com/content/image/1-s2.0-S2352304225004659-gr1_lrg.jpg

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Credit: Genes & Diseases





A new review highlights how advances in DNA technology are reshaping the future of healthcare by shifting the focus from treatment to prevention. Cutting-edge tools are enabling earlier detection of risk and more precise intervention at the genetic level, offering the potential to stop diseases before symptoms ever appear.

Central to this transformation is CRISPR-Cas9 gene editing, a powerful method that allows scientists to correct defective genes with remarkable accuracy. This approach is opening new possibilities for preventing inherited conditions such as cystic fibrosis and sickle cell disorders, while also contributing to innovations in cancer prevention and immune system enhancement.

Alongside gene editing, advances in epigenetic modification are revealing how environmental and lifestyle factors influence gene activity. By targeting these reversible changes, new strategies are emerging to reduce the risk of chronic illnesses, including cancer and metabolic disorders. This marks a significant evolution in understanding how gene expression can be managed without altering the DNA sequence itself.

The review also emphasizes the importance of RNA-based therapies, which are rapidly gaining momentum as tools for regulating gene activity and preventing disease progression. Technologies such as mRNA platforms have already demonstrated their value in public health and are now being adapted for broader applications, including cancer prevention and rare genetic conditions.

Another promising avenue is somatic cell genome editing, which targets non-reproductive cells to correct genetic abnormalities without affecting future generations. This approach provides a practical and ethically viable pathway for applying gene editing in clinical settings, reducing concerns associated with heritable genetic changes.

In addition, innovations such as next-generation sequencing, synthetic biology, and AI-driven genome analysis are enhancing the ability to identify disease risk early and tailor interventions to individual genetic profiles. These technologies are driving the shift toward personalized medicine, where prevention strategies are designed around each person’s unique biology.

Despite the promise, challenges remain, including ensuring safety, improving delivery methods, and addressing ethical considerations. However, the continued evolution of these technologies signals a future where healthcare is increasingly predictive, personalized, and proactive.

Together, these advancements underscore a transformative moment in medicine, where mastering the molecular foundations of life is enabling a new era of disease prevention with far-reaching global impact.

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Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular bases of human diseases. Emphasis is placed on hypothesis-driven, mechanistic studies relevant to pathogenesis and/or experimental therapeutics of human diseases. The journal has worldwide authorship, and a broad scope in basic and translational biomedical research of molecular biology, molecular genetics, and cell biology, including but not limited to cell proliferation and apoptosis, signal transduction, stem cell biology, developmental biology, gene regulation and epigenetics, cancer biology, immunity and infection, neuroscience, disease-specific animal models, gene and cell-based therapies, and regenerative medicine.

Scopus CiteScore: 10.4 |Impact Factor:14.6

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More information: https://www.keaipublishing.com/en/journals/genes-and-diseases/
Editorial Board: https://www.keaipublishing.com/en/journals/genes-and-diseases/editorial-board/
All issues and articles in press are available online in ScienceDirect (https://www.sciencedirect.com/journal/genes-and-diseases).

Submissions to Genes & Diseases may be made using Editorial Manager (https://www.editorialmanager.com/gendis/default.aspx).

Print ISSN: 2352-4820
eISSN: 2352-3042
CN: 50-1221/R
Contact Us: editor@genesndiseases.cn
X (formerly twitter): @GenesNDiseases (https://x.com/GenesNDiseases)



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Image Caption: CRISPR-Cas9 gene editing process.

Image link https://ars.els-cdn.com/content/image/1-s2.0-S2352304225004659-gr2_lrg.jpg

Credit

Genes & Diseases

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Image Caption: Flow chart of the mechanism of in vivo somatic cell genome editing.

Image link https://ars.els-cdn.com/content/image/1-s2.0-S2352304225004659-gr3_lrg.jpg

Credit

Genes & Diseases

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Reference

Giri Rajasekhar Dornadula, Ramakrishna Chilakala, Sadak Basha Shaik, Pramod Kumar Meriga, Likhitha Chintha, Yeshwanth Gurugari, Kranthi Kumar D, Sameena Fatima Shaik, Sun Hee Cheong, Molecular mastery: Harnessing DNA technology for disease prevention, Genes & Diseases, Volume 13, Issue 4, 2026, 101976, https://doi.org/10.1016/j.gendis.2025.101976

 

Funding

University Industry Liaison of Chonnam National University 2025-0929

Ministry of Education (MOE) and the Jeollanamdo, Republic of Korea 2025-RISE-14-007

 

U.S. disease tracker launches to strengthen monitoring of vaccine-preventable diseases



Site initially tracks measles, meningitis and whooping cough at state/substate levels with detailed visualizations




Johns Hopkins University

New U.S. disease tracker graphics 

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The tracker will initially monitor cases of measles, meningitis and pertussis (whooping cough), and later be expanded to include other vaccine-preventable diseases.

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Credit: U.S. Disease Tracker





A new website will track the spread of vaccine-preventable diseases across the United States to offer the public, the media, healthcare providers, public health officials, and policymakers reliable and visual information about current disease trends.

The U.S. Disease Tracker, created and run by Johns Hopkins University, the Association of State and Territorial Health Officials, and the Council of State and Territorial Epidemiologists, in partnership with state and territorial public health agencies, will initially monitor cases of measles, meningitis and pertussis (whooping cough), and later be expanded to include other vaccine-preventable diseases.

The tracker builds on and complements the Centers for Disease Control and Prevention’s national disease surveillance infrastructure by providing open access data that is timely, detailed and designed for broad audiences.

“The COVID-19 pandemic elucidated both the value of timely and accessible public health data, as well as the importance of data standardization,” said project co-lead Lauren Gardner, director of Johns Hopkins’ Center for Systems Science and Engineering, an expert in using data and modeling to better understand the spread of disease. “What makes this tracker unique is its foundation in standardized and validated public health data. The partnership enables a more complete and epidemiologically meaningful view of disease activity and transmission patterns, and a more reliable resource for public health professionals, policymakers, researchers, and the public.”

The tracker presents and displays data in a standardized format that is comparable across the participating jurisdictions, enabling more accurate and uniform representation of national disease trends.

Cases are tracked at the state and sub-state level, with detailed visualizations designed to capture disease trends across the U.S. and over time.

Cases are additionally reported by age group to illustrate the most affected populations.

To date, over 25 jurisdictions have committed to joining the effort. Currently, data from 10 participating states are directly reflected on the tracker, with more than 15 additional jurisdictions committed to begin participating in 2026.

“By providing easy to understand maps, figures, and analyses of vaccine preventable diseases in the United States, we hope to guide public health policy decisions and inform health care providers so they can better advise and care for their patients,” said project co-lead William Moss, senior advisor at the Johns Hopkins’ International Vaccine Access Center and an epidemiologist at the Bloomberg School for Public Health. “The tracker offers a critical resource for enabling informed decision making and protecting the health of communities.”

The tracker, developed through a collaboration between academia and public health, draws on the expertise of health department leaders and frontline practitioners to ensure it meets real-world public health needs. “We have carefully designed this effort with our public health partners to maximize the data’s usefulness while maintaining non-identifiability and data security. We hope this can set the stage for a new paradigm for efficient and collaborative use of data for public health,” said project co-lead Shaun Truelove, executive director of the Johns Hopkins’ International Vaccine Access Center and an expert in infectious disease modeling with the Bloomberg School of Public Health.

Data for the tracker is voluntarily provided by the health departments of participating jurisdictions. For non-participating states, the data comes from the CDC’s National Notifiable Diseases Surveillance System.

Collaborators at Johns Hopkins also include the Bloomberg Center for Government Excellence, the Data Science and AI Institute and the Institute for Data Intensive Engineering and Science.

Visit the U.S. Disease Tracker: usdiseasetracker.org

New U.S. disease tracker maps 

Cases are tracked at the state and sub-state level, with detailed visualizations designed to capture disease trends across the U.S. and over time.

Credit

U.S. Disease Tracker

 

German cockroaches appear to be more social animals than previously thought




North Carolina State University





Newborn German cockroaches use pheromones in cockroach feces to identify members of their own colony and form a kind of social bond, a discovery which could be used to improve pest control efforts.

Scientists compared neonate cockroaches that had been allowed to consume their colony’s feces and were exposed to fecal odors to neonates that had not engaged in coprophagy. German cockroaches are born with no gut microbiome, and rely on eating feces from a collective fecal pile within their cockroach “aggregation” to gain the microbes and fecal nutrients they need.

Neonates who ate from the aggregation’s feces after hatching displayed an affinity for the specific pheromone present in that aggregate, while the neonates without any microbiome – known as naïve neonates – showed a much broader and less focused array of interests.

“This finding could be used to help control cockroach infestations,” said Ayako Wada-Katsumata, lead author of the paper and a principal research scholar in North Carolina State University’s Department of Entomology and Plant Pathology.

“What we’ve found is that aggregation pheromones are extremely important in how these cockroaches find each other and group together,” says Wada-Katsumata. “Because the aggregation gives these neonates everything they need early in life, they have little reason to leave it, which makes traps and insecticidal baits less effective.

“If we can develop an aggregation pheromone that works across the entire species, we could make traps and baits far more effective and make it easier to control populations in places like residences, hospitals, and restaurants.”

Beyond the practical applications, this research also unveils a fundamental misunderstanding about cockroach social structures, said Coby Schal, co-author of the paper and the Blanton J. Whitmire Distinguished Professor of Entomology at NC State.

“We think of cockroaches as being subsocial, in that they are not completely solitary but also do not exhibit the kinds of group behaviors that bees or ants do,” Schal said. “The use of fecal aggregation pheromones to recognize their natal group is a behavior that mirrors that of social insects like bees, wasps, ants and termites, which typically use body odors instead of fecal odors to recognize nest-mates. Both groups of insects share a similar mechanism that involves learning and memory of their colony’s unique odor, but the anatomical source of the pheromone is different.”

This behavior implies a greater capacity for social structure and learning than has often been attributed to the German cockroach, Schal said.

“What we’re seeing here is a capacity for learning and memory retention that is often thought of as being above an insect as primitive as the cockroach,” he said. “Cockroaches have evolved their own twist on forming kin bonds.”

The paper, “Group recognition in the German cockroach, a subsocial omnivore, is based on faecal odour preference that is modulated by coprophagy, diet and learning,” is published in Proceedings B. Co-authors include Jamora A. Hamilton-Brown and Madhavi L. Kakumanu of NC State University.

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Note to editors: The abstract of the paper follows.

“Group recognition in the German cockroach, a subsocial omnivore, is based on faecal odour preference that is modulated by copraphagy, diet and learning”

Authors: Ayako Wada-Katsumata, Coby Schal, Jamora A. Hamilton-Brown, Madhavi L. Kakumanu; NC State University.

Published: August 5, 2026 in Proceedings B.

DOI: 10.1098/rspb.2025.3042

Abstract: Fecal odors attract cockroaches to aggregations, where conspecific feces provide nutrients and seed the gut microbiota. Because these odors arise from the gut and fecal microbial communities, which are shaped by coprophagy and diet, discrete aggregations within a heterogeneous landscape can produce distinct fecal odor profiles. How such odor diversity influences recognition, group-affiliation and ultimately aggregation remains unclear. We manipulated coprophagy and then diet quality in gnotobiotic nymphs to generate groups with distinct fecal odor signatures, then raised them to the adult stage and collected their feces for behavioral assays. Naïve nymphs lacking coprophagy experience were equally attracted to fecal odors from all treatment groups, suggesting an innate attraction to conspecific feces. In contrast, experienced nymphs preferred the fecal odor of their natal group over foreign groups, suggesting learned group-specific recognition. In associative learning assays pairing a fecal odor with a glucose reward, nymphs preferentially aggregated with the conditioned odor over novel odors. These results show that aggregation in neonate cockroaches is mediated by both an innate attraction to conspecific fecal odor and learned preferences for specific odorants encountered during coprophagy soon after they hatch. We propose that these mechanisms guide neonates toward natal aggregations, facilitating acquisition of a locally adapted gut microbial community.

 

When we misread autistic people, it may not be a lack of empathy—it may be a mismatch





The Hebrew University of Jerusalem
Dr. Yonat Rum 

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Dr. Yonat Rum

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Credit: (Credit- Arkadi Voronin)





A new study reveals important nuances in how autistic and non-autistic people understand one another. Guided by the Double Empathy Problem theory, research suggests that communication difficulties are often mutual rather than stemming from a one-sided "empathy deficit," in autistic people. Using a novel empathy test based on real-life emotional stories, the researchers found that autistic participants were just as capable of understanding others' emotions, challenging long-held assumptions about autism and highlighting the importance of mutual understanding.

[Hebrew University of Jerusalem]– For years, autism has often been viewed through the lens of a simple assumption: that autistic people struggle to understand how others feel. However, accumulating research over recent years suggests the picture is far more complex. This new study, led by Dr. Yonat Rum from the Hebrew University, adds to this evidence and offers a more hopeful perspective.

According to the Double Empathy Problem theory, communication difficulties and misunderstandings arise between autistic and non-autistic people because they experience and communicate emotions differently, making it harder for both sides to accurately understand one another.

To explore this, researchers created a novel test designed to measure empathy that goes beyond traditional questionnaires. They recorded autistic and non-autistic adults sharing their real-life emotional stories. Hundreds of participants then watched the videos and continuously rated what they believed each storyteller was feeling, allowing researchers to compare those judgments with how the storytellers themselves described their emotions.

Surprisingly, the researchers found no evidence that autistic people were worse at understanding others' emotions. Instead, autistic and non-autistic participants performed similarly when it came to accurately tracking emotional experiences. The findings also suggested that autistic participants may have been slightly more accurate at understanding other autistic storytellers, although the effect was modest.

One of the most striking findings was that people who reported feeling more empathy were not necessarily better at understanding what others were actually feeling. Although non-autistic participants rated themselves as more empathic and more interested in the storytellers, they were no more accurate than autistic participants in identifying the storytellers’ emotions.

The study also invited participants to describe their experiences after completing the task. Autistic participants often reflected deeply on the challenge of identifying emotions and described carefully thinking through their responses, while non-autistic participants were more likely to comment on the design of the task itself. These reflections suggest that autistic people may approach emotional understanding differently rather than less effectively.

These findings carry an important message. When an autistic person seems misunderstood—or appears to misunderstand someone else—it may not mean they lack empathy. Instead, it could be that the communication styles of autistic and non-autistic people may not naturally align. Recognizing this difference can help families, teachers, and clinicians focus less on "fixing" autistic individuals and more on building mutual understanding between  autistic and non-autistic people.

The researchers hope their work will encourage future studies of real-world social interactions and relationships, moving beyond outdated assumptions that place the responsibility for communication difficulties solely on autistic individuals.