Thursday, January 30, 2025

 


How to avoid the next crypto collapse: a new study unveils the factors behind cryptocurrency exchange failures




University of Vaasa
Assistant Professor Niranjan Sapkota, University of Vaasa, Finland 

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Assistant Professor Niranjan Sapkota, University of Vaasa, Finland

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Credit: University of Vaasa, Riikka Kalmi




Imagine logging into your cryptocurrency exchange platform one morning only to find the website down, your funds gone, and no one to answer your questions. This nightmare has been a harsh reality for thousands of traders, with nearly 500 cryptocurrency exchanges having already failed. A new study from the University of Vaasa, Finland, sheds light on the risk factors in cryptocurrency exchanges.

In his study, published in the valued Journal of International Financial Markets, Institutions & Money, Assistant Professor Niranjan Sapkota analyses data from 845 cryptocurrency exchanges to investigate why nearly half of these exchanges have collapsed since 2014 and how to predict such defaults. He identifies several key indicators including transparency, centralisation, territorial access, fee structures, coin listings, referral schemes, etc., offering valuable insights into mitigating risks in this evolving market.

 

When transparency becomes a double-edged sword

Centralised exchanges in developed, transparent, and well-regulated countries, such as United States and Singapore are often perceived as the safest. According to the study, they are surprisingly fragile. This fragility arises from pressures such as stringent regulations, high compliance costs, and advanced infrastructures that fraudsters can exploit for illicit activities. In contrast, developing nations, where cryptocurrency adoption remains under policy debate, face fewer such challenges.

– Even more strikingly, exchanges that allow U.S. customers to trade experience higher probability of default compared to those that restrict U.S. clients, Sapkota adds.

All in all, centralised exchanges, which manage wallet custody on behalf of users similar to how traditional banks manage accounts, have a higher risk of default than decentralised exchanges (DEXs), where users retain self-custody of their assets and conduct transactions directly on the blockchain. DEXs have a 31.2% lower probability of failure compared to centralised platforms, as their distributed structure mitigates risks related to fraud, operational mismanagement, and liquidity crises.

 Warning signs: high fees, limited coin listings and poor ratings

According to the study, high withdrawal fees often signal financial instability. Defaulted exchanges charged withdrawal fees on average 1.5 times higher than operational ones.

Furthermore, exchanges offering a wide variety of cryptocurrencies and maintaining high user ratings are more likely to survive. A diverse range of cryptocurrencies attracts a larger user base and ensures steady revenue streams whereas high user ratings typically reflect strong operational practices. The study also indicated that exchanges with referral incentives are less likely to default.

– So, next time a friend shares a legitimate crypto exchange referral link, don’t dismiss it as mere bonus hunting, says Dr. Sapkota.

 

Robust results for creating a safer crypto ecosystem

This cutting-edge research bridges a critical knowledge gap in the emerging field of cryptocurrency exchange risk, offering the knowledge needed to approach the market with greater confidence, and actionable solutions for more secure blockchain-based digital asset trading platforms.

The study also highlights the effectiveness of traditional statistical methods, such as logit and probit models, in predicting cryptocurrency exchange bankruptcies, achieving an accuracy rate of approximately 81%. Cutting-edge machine learning techniques, including Random Forest, Support Vector Machine, and Stacked Ensemble, validate these findings.

– Policy makers can leverage these findings to design policies that protect users and strengthen market stability. Investors and traders can learn to spot critical red flags – such as poor ratings, excessive withdrawal fees, limited coin offerings, centralised exchanges, and U.S. client access – to avoid unreliable platforms and safeguard investments, Sapkota explains the applications of his research. 

 

Further information

Sapkota, N. (2025) The Crypto Collapse Chronicles: Decoding Cryptocurrency Exchange Defaults. Journal of International Financial Markets, Institutions & Money. Vol. 99, article 102093.

https://doi.org/10.1016/j.intfin.2024.102093

 

 SPACE/COSMOS

Small and yet so powerful


The hidden power of the smallest microquasars



Max-Planck-Institut fur Kernphysik

Artist’s impression of a microquasar system 

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A star and a black hole orbit each other closely: mass from the star is captured by the black hole. As a consequence of this, a pair of jets launch away from the black hole.

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Credit: Science Communication Lab for MPIK/H.E.S.S.




  • The production and acceleration of the highest energetic cosmic rays (charged particles) are still one of the biggest mysteries in astroparticle physics.

  • Very efficient acceleration of cosmic particles seems to happen in the jets of microquasars. However, up until now this was only observed in rare high-mass-microquasar systems.

  • Researcher have now for the first time found evidence of particle acceleration in the much more abundant low mass-systems, with significant implications for the estimated contribution of microquasars as a group to the cosmic ray content of our Galaxy

 

Our home planet is bombarded with particles from outer space all the time. And while we are mostly familiar with the rocky meteorites originating from within our solar system that create fascinating shooting stars in the night sky, it’s the smallest particles that help scientists to understand the nature of the universe. Subatomic particles such as electrons or protons arriving from interstellar space and beyond are one of the fastest particles known in the universe and known as cosmic rays.

The origins and the acceleration mechanisms of the most energetic of these cosmic particles remains one of the biggest mysteries in astrophysics. Fast-moving matter outflows (or “jets”) launched from black holes would be an ideal site for particle acceleration, but the details on how and under which conditions acceleration processes can occur are unclear. The most powerful jets inside our Galaxy occur in microquasars: systems composed by a stellar-mass black hole and a “normal” star. The pair orbit each other, and, once they are close enough, the black hole starts to slowly swallow its companion. As a consequence of this, jets are launched from the region close to the black hole.

In the past couple of years there has been growing evidence that microquasar jets are efficient particle accelerators. It is however unclear how much they contribute, as a group, to the total amount of cosmic rays in the Galaxy. The answer to this question requires understanding if all microquasars are able to accelerate particles or only a lucky few.

Microquasars are usually classified depending on the mass of the star in the system into either “low-mass” or “high-mass” systems, with lower-mass systems being much more abundant. However, up until now evidence of particle acceleration was only found for the high-mass systems. For example, the microquasar SS 433, which was recently revealed to be one of the most powerful particle accelerators in the Galaxy, contains a star with mass approximately ten times that of the Sun. Consequently, it was generally believed that low-mass microquasars were not powerful enough to produce gamma-rays. Dr. Laura Olivera-Nieto from the Max-Planck-Institut für Kernphysik in Heidelberg, Germany (MPIK) and Dr. Guillem Martí-Devesa from the Università di Trieste, Italy have now made a discovery that shakes this paradigm. They used 16 years of data from the Large Area Telescope detector onboard NASA’s satellite Fermi to reveal a faint gamma-ray signal consistent with the position of GRS 1915+105, a microquasar with a star smaller than the Sun. The gamma-ray signal is measured to have energies higher than 10 GeV, indicating that the system could accelerate particles to even higher energies.

The observations favor a scenario in which protons are accelerated in the jets, after which they escape and interact with nearby gas to produce gamma-ray photons. In the paper, published in the Astrophysical Journal Letters, they also use data from the Nobeyama 45-meter radio telescope in Japan, which indicates that there is enough gas material around the source for this scenario.

This result shows that even microquasars hosting a low-mass star are capable of particle acceleration. Because this is the most numerous class, this finding has significant implications for the estimated contribution of microquasars as a group to the cosmic ray content of our Galaxy. However, more detections and multi-wavelength studies will be required in order to further narrow down why some systems accelerate particles efficiently but not all.

 

Global Young Academy members and alumni publish Nature article exploring academic success in 121 countries



Researchers from the Global Young Academy (GYA) Scientific Excellence working group have published an article in the journal Nature examining the criteria used to measure success in academia




Global Young Academy

GYA members and alumni publish Nature article exploring academic success in 121 countries 

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GYA members and alumni author Nature article titled “Regional and institutional trends in assessment for academic promotion"

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Credit: GYA




28 January 2025 – Researchers from the Global Young Academy (GYA) Scientific Excellence working group have published an article in the journal Nature examining the criteria used to measure success in academia.

Having carried out a first truly global analysis of 532 policies adopted by institutions or government agencies from 121 countries on the promotion to the post of (full) professor, the authors found that publication and citation metrics are not uncommon, but surprisingly, policies affecting approximately three-quarters of researchers around the globe do not contain an explicit reference to citations. Rather, mentoring, administrative responsibilities, as well as contributions to the field or scientific community frequently play a role.

Unlike previous studies that focused on the prominence of criteria, the findings from this publication result from an approach that looked for both commonalities and differences, as well as the clustering of criteria within given policies.

This approach revealed four characteristic profiles of assessment – those considering (1) output metrics, (2) visibility & engagement, (3) career development, and (4) outcomes & impact.

GYA alumnus Martin Dominik (University of St Andrews, United Kingdom) an initiator of the study, points out that “Research institutions around the world are not identical and interchangeable, criteria differ, and anyone interested in a job in academia should be well aware of specificities.”

The pervasiveness of evaluation metrics means that universities are under pressure by rankings that set their own criteria. Still, some adopted assessment criteria are quite contrary to what an institution wants to achieve and some particularly reward bad practices, including fraud and anti-social behavior within the research community.

Many differences were found between countries, with simple publication and citation metrics being particularly popular in upper middle-income countries, aspiring to close the gap to stronger economies. Such metrics have a clear appeal due to providing an easy and straightforward way to measure progress or success. But these lose purpose on failing to align with goals that adequately serve society in the specific environment.

Moreover, many popular metrics come with systemic disadvantages for less-developed countries and researchers working there. Focusing on those as measures of success results in engaging in a competition that cannot be won and staying behind forever, rather than embracing opportunities based on specific strengths that enable leaping ahead.

Building assessment around normative career paths ignores that candidates faced different challenges under different circumstances and within different environments. Such an approach also creates substantial obstacles to inter-sectoral mobility across academia, industry, government, and not-for-profit organisations.

Evaluation practices that are shaped by a universal “excellence” narrative not only fail to support the specific goals of institutions, but moreover restrict academic diversity and reinforce Global North-South inequalities.

GYA Co-Chair Yensi Flores Bueso (University College Cork/University of Washington, Ireland/United States), concludes “I hope that this work provides a foundation to rethink policies so that they foster equity, inclusivity, and research integrity as fundamental pillars of our research culture, and that consequently science can serve as a common good for humanity as a whole.”

Read the Nature article here: “Regional and institutional trends in assessment for academic promotion”.

Related media:

Nature podcast:.https://www.nature.com/articles/d41586-025-00206-z

Nature news item: https://www.nature.com/articles/d41586-025-00143-x

Science news item: https://www.science.org/content/article/when-promoting-professors-research-productivity-matters-some-universities-more-others

Times Higher Education news item: https://www.timeshighereducation.com/news/global-south-professorial-promotions-rely-too-much-metrics#:~:text=Academics%20in%20the%20Global%20South,which%20%E2%80%9Creinforce%20regional%20inequalities%E2%80%9D

Phys.org news item: https://phys.org/news/2025-01-criteria-full-professorship-vary-greatly.html

World Today News item: https://www.world-today-news.com/professor-promotions-in-developing-world-overly-dependent-on-metrics-study-reveals/#google_vignette

About the Global Young Academy
The vision of the GYA is science for all; science for the future, and its mission is to give a voice to young scientists and researchers around the world. The GYA, founded in 2010, is an independent science academy of 200 outstanding early- to mid-career researchers from six continents who are selected from across disciplines based on their academic excellence and commitment to engage with society. GYA members serve five-year terms, and the GYA presently counts members and alumni from around 100 countries. The GYA administrative Office is publicly funded and hosted at the German National Academy of Sciences Leopoldina. 

Contact person for the media: James.Curtiss@globalyoungacademy.net

 

New insights into the perception of coffee taste - genetic predisposition plays a role



Why does coffee taste more bitter to some people than it does to others? Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have now come closer to answering this question




Leibniz-Institut für Lebensmittel-Systembiologie an der TU München

Coline Bichlmaier and Dr. Roman Lang in the lab 

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The photo shows two scientists from the Leibniz-Institute for Food Systems Biology at the Technical University of Munich conducting research into coffee flavor in the laboratory. They are wearing lab coats and protective goggles.

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Credit: photo: G. Olias / Leibniz-LSB@TUM




Why does coffee taste more bitter to some people than it does to others? Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have now come closer to answering this question. They have identified a new group of bitter compounds in roasted Arabica coffee and have investigated how they influence its bitter taste. In addition, they demonstrated for the first time that individual genetic predisposition also plays a role in determining how bitter these roasting substances taste.

Although caffeine has been known as a bitter tasting substance for a long time, even decaffeinated coffee tastes bitter. This shows that other substances also contribute to the bitter taste of roasted coffee. Coline Bichlmaier, a doctoral student at the Leibniz Institute, explains: “Indeed, previous studies have identified various compound classes that are formed during roasting and contribute to bitterness. During my doctoral thesis, I have now identified and thoroughly analyzed another class of previously unknown roasting substances.”

The starting point of her research was the mozambioside contained in Arabica beans. It tastes about ten times more bitter than caffeine and activates two of the approximately 25 bitter taste receptor types found in the human body, namely the TAS2R43 and TAS2R46 receptors. “However, our investigations showed that the concentration of mozambioside decreases significantly during roasting, so that it only makes a small contribution to the bitterness of coffee,” says principal investigator Roman Lang, and continues: ”This prompted us to test whether roasting produces breakdown products of mozambioside are also bitter and could affect coffee’s taste.”

Combination effect and genetic predisposition are important

As the research team shows, seven different degradation products of mozambioside are formed during roasting. These compounds are found in roasted coffee in varying concentrations, depending on roasting temperature and duration, and almost completely pass into the beverage during brewing.

Investigations in a cellular test system established at the institute show that these roasting substances activate the same bitter taste receptor types as mozambioside. Three of the roasting products even had a stronger effect on the receptors than the original compound. However, the researchers found that the concentrations of these roasting products measured in brewed coffee were too low to induce a noticeable taste on their own. Only the combination of mozambioside and its roasting products in a sample led eight out of eleven test subjects to perceive a bitter taste. One person found the taste astringent and two did not perceive any particular taste.

A genetic test showed that taste sensitivity depended on the genetic predisposition of the test subjects: two people had both copies of the TAS2R43 gene variant defective. Seven had one intact and one defective variant of the receptor and only two people had both copies of the gene intact.

What do the results mean for the future?

“The new findings deepen our understanding of how the roasting process influences the flavor of coffee and open up new possibilities for developing coffee varieties with coordinated flavor profiles. They are also an important milestone in flavor research, but also in health research,” says Roman Lang, explaining: ”Bitter substances and their receptors have further physiological functions in the body, most of which are still unknown.” According to Lang, there is still a lot of work to be done, since for many bitter substances in coffee alone, it is not yet known which bitter taste receptors they activate, even though millions of people worldwide drink coffee every day.

Publications:

1) Bichlmaier, C., Fröhlich, S.M., Brychcy, V., Grassl, A., Behrens, M., and Lang, R. (2024). Contribution of mozambioside roasting products to coffee's bitter taste. Food Chem 469, 142547. 10.1016/j.foodchem.2024.142547. https://doi.org/10.1016/j.foodchem.2024.142547

2) Czech, C., Lang, T., Graßl, A., Steuer, A., Di Pizio, A., Behrens, M., and Lang, R. (2024). Identification of mozambioside roasting products and their bitter taste receptor activation. Food Chem 446, 138884. 10.1016/j.foodchem.2024.138884. https://doi.org/10.1016/j.foodchem.2024.138884

More information

Mozambioside
Arabica coffee contains bitter-tasting mozambioside (11-O-β-D-glucosyl-cafestol-2-one). It is a hydrophilic derivative of cafestol that is particularly abundant in naturally caffeine-free varieties. Its perception threshold in humans is 60 ± 10 micromolar (Lang et al., 2015Lang et al., 2020). Its concentration in raw Arabica coffee is about 0.4–1.2 micromol/g. Roasting breaks down the substance to below the taste threshold in the end product.

Other bitter-tasting roasting substances in coffee
The most important bitter tasting substances that are reportedly formed during roasting include caffeoylquinides, which are formed from chlorogenic acids, diketopiperazines, which originate from coffee proteins, and oligomers of 4-vinylcatechols, which are formed from caffeic acids. These compound classes do impart a bitter taste, but it is not yet known which bitter taste receptor types mediate their perception.

Bitter taste receptors
In humans, about 25 different taste receptor types are responsible for the perception of bitter substances. These bitter taste receptors are not only found in the mouth, but also on cells of other organs and tissues. The many functions they perform there are the subject of numerous studies, including those conducted at the Leibniz Institute for Food Systems Biology at the Technical University of Munich. Various studies already indicate that bitter taste receptors in the respiratory tract help to ward off pathogens and accelerate the movement of cilia. They also suggest that endogenous bitter receptors in the intestines and blood cells support defense mechanisms or are involved in the regulation of metabolism.

Per capita coffee consumption in selected countries worldwide in 2023
https://de.statista.com/statistik/daten/studie/199898/umfrage/konsum-von-kaffee-in-europa/

Global coffee production by variety up to 2023/24
In the production year 2023/24, around 102.2 million 60-kilo bags of Arabica coffee were produced worldwide. For Robusta, the figure was 75.8 million 60-kilo bags.
https://de.statista.com/statistik/daten/studie/224824/umfrage/weltweite-kaffeeproduktion-nach-sorten/

Information About the Institute:

The Leibniz Institute for Food Systems Biology at the Technical University of Munich (Leibniz-LSB@TUM) comprises a new, unique research profile at the interface of Food Chemistry & Biology, Chemosensors & Technology, and Bioinformatics & Machine Learning. As this profile has grown far beyond the previous core discipline of classical food chemistry, the institute spearheads the development of a food systems biology. Its aim is to develop new approaches for the sustainable production of sufficient quantities of food whose biologically active effector molecule profiles are geared to health and nutritional needs, but also to the sensory preferences of consumers. To do so, the institute explores the complex networks of sensorically relevant effector molecules along the entire food production chain with a focus on making their effects systemically understandable and predictable in the long term.

The Leibniz-LSB@TUM is a member of the Leibniz Association, which connects 96 independent research institutions. Their orientation ranges from the natural sciences, engineering and environmental sciences through economics, spatial and social sciences to the humanities. Leibniz Institutes address issues of social, economic and ecological relevance.They conduct basic and applied research, including in the interdisciplinary Leibniz Research Alliances, maintain scientific infrastructure, and provide research-based services. The Leibniz Association identifies focus areas for knowledge transfer, particularly with the Leibniz research museums. It advises and informs policymakers, science, industry and the general public.

Leibniz institutions collaborate intensively with universities – including in the form of Leibniz ScienceCampi – as well as with industry and other partners at home and abroad. They are subject to a transparent, independent evaluation procedure. Because of their importance for the country as a whole, the Leibniz Association Institutes are funded jointly by Germany’s central and regional governments. The Leibniz Institutes employ around 21,300 people, including 12,200 researchers. The financial volume amounts to 2,2 billion euros.

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Weather change linked to increased risk of Salmonella outbreaks



University of Surrey




Climate change is impacting the spread of Salmonella, according to new research from the University of Surrey. This research follows previous work from the team, which found that weather change is leading to the spread of dangerous diarrheal illness. 

The study, led by a team of researchers at Surrey’s School of Veterinary Medicine, investigated the impact of different weather factors on the transmission of Salmonella - a leading cause of foodborne illnesses in Europe, accounting for nearly one in three foodborne outbreaks. 

Salmonella is a type of bacteria that can cause food poisoning. It’s found in the intestines of animals and humans and can contaminate food if it’s not cooked or handled properly. Salmonella can cause diarrhoea, fever, and stomach cramps, and it is most prominent in areas with poor sanitation and hygiene. 

In the study, published in the Journal of Infection, researchers compared UK Health Security Agency (UKHSA) data of confirmed cases of Salmonella in England and Wales during 2000-2016 with Met Office data of the time, focusing on 14 different weather factors. This provided a more holistic understanding, which considered the combined effect of multiple weather factors on incidences of Salmonella, leading to an in-depth description of the risk of salmonellosis when we know the local weather during the past days. 

Warmer temperatures (above 10 degrees Celsius), relative humidity, dewpoint temperature (between 7-10 degrees Celsius), and longer days (over 12-15 hours) were identified as key weather factors associated with an increase in Salmonella cases, irrespective of geographical location. These findings were also validated by analysing data from the Netherlands. 

Dr Gianni Lo Iacono, Senior Lecturer in Biostatistics and Epidemiology at the University of Surrey, said: 

“The model we used to analyse the data shows promise, as the findings were replicated across England, Wales and, independently,  in the Netherlands, suggesting a potential for wider application in other European and high-income countries to help gain new insights on the incidence of Salmonella. It would be interesting to investigate this in regions with very different environmental and socio-economic characteristics, like tropical countries.” 

Dr Laura Gonzalez Villeta, the first author of the study and researcher at the University of Surrey, said: 

“The study highlights how weather plays a significant role in Salmonella outbreaks and provides a valuable tool for predicting future risks and tailoring interventions, particularly in the context of climate change.” 

[ENDS] 

  • The full paper is available at the Journal of Infection: https://www.sciencedirect.com/science/article/pii/S0163445325000040 

  • An image of Dr Gianni Lo Iacono is attached.