Wednesday, March 05, 2025

 

Generations ‘sync’ up in rural ‘glades’ to boost technology use for health



Nursing study pairs teens, older adults with smartwatches to test monitoring health in under-resourced communities




Florida Atlantic University

Monitoring Health in Under-resourced Communities 

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Lisa Ann Kirk Wiese, Ph.D., senior author, (seated, center) with members of the faith-based community team who worked with the students.

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Credit: Florida Atlantic University




Given the growing role of mobile technology in supporting older adults, it’s essential to implement initiatives that encourage its adoption among this population. However, older adults are often unfamiliar with mobile technology, especially those in rural areas with limited digital access or literacy.

To bridge this gap, researchers from Florida Atlantic University’s Christine E. Lynn College of Nursing, and collaborators, implemented a pilot study to test an intergenerational program involving high school students, older adults and local faith-based health educators in the “Glades,” a rural community nestled at the southern tip of Lake Okeechobee in South Central Florida.

Older residents in this tight-knit community share a strong desire to maintain healthy habits that support aging in place. However, their ability to track and monitor these habits using wireless fitness devices like Fitbits and smartwatches is hindered by the area’s limited resources and the difficulties many residents have with mobile technology literacy.

The impetus for the community-driven study in this under-resourced area was for older residents (ages 53 to 84) to embrace technology and gain greater acceptance and use of health-tracking devices as well as assessing everyday brain health behaviors.

For the study, an ecological momentary assessment (EMA) was used to deliver health-related survey questions via a smartwatch four times a day asking questions like “In the past two hours, how much social contact have you had?,” “How physically active have you been?” and “How mentally engaged have you been?” In addition, paper-and-pencil assessments were used to screen for cognition, health literacy and technology competence. Researchers explored the relationships between these screening measures and the usage of the smartwatch.

Results, published in the journal Educational Gerontology, showed that 91% of older adults engaged with the smartwatch prompts, with an overall response rate of 77.8%. Interestingly, response rates were not influenced by factors such as health literacy, technology self-efficacy, self-reported cognitive status, education, age or rural living. Additionally, social contact was found to be positively associated with physical activity, mental engagement and the perception of having a “sharp mind,” highlighting the importance of social engagement for brain health. The training process and the use of smartwatches proved effective for participants with varying levels of technology and health literacy.

“Our study created a win-win situation for everyone involved: older adults gained new skills in using wearable technology to monitor their health, while high school students had the opportunity to learn processes for conducting meaningful research and develop valuable skills,” said Lisa Ann Kirk Wiese, Ph.D., senior author and an associate professor, Christine E. Lynn College of Nursing. “Faith-based health educators, trusted figures within their communities, were able to contribute to the well-being of those they serve, fostering a sense of empowerment and connection across generations.”

For the study, participants wore the smartwatch for at least two weeks and received a simultaneous ringtone and vibration for each prompt. High school students (ages 15-19) trained participants on how to wear the smartwatch and respond to prompts using step-by-step guides. They assisted with setup, including charging the watch and understanding prompt timings, and offered additional support during follow-up visits.

Before participants began using the smartwatches, faith-based health educators administered surveys, with high school students often present. Participants also completed a brief cognitive screening (Borson’s Mini-Cog©), health literacy assessment, and a sociodemographic survey during the initial screening.

Students expressed gratitude for the opportunity to participate in a research initiative, with many seeking further research-related positions or scholarships. They valued the chance to add this experience to their resumes. All participants agreed they would likely never have used a smartwatch without the students’ guidance. Participants with more years of education expressed that wearing the smartwatch was particularly enjoyable and they were curious about their progress. For those with less education, more hands-on training was needed. Both students and older adults appreciated the time spent together, with students gaining valuable skills like teaching technology, patience and empathy. They also felt a sense of responsibility and open-mindedness.

“High school students don’t just teach older adults about mobile health – they also gain invaluable skills and insights themselves,” said Wiese. “Through these meaningful interactions, students discover how technology can improve health monitoring and care, while being inspired to pursue careers in aging, health care and gerontechnology. These experiences not only prepare them for future careers but also foster a deep appreciation for the power of digital health in their own lives.”

Through community-based participatory research, the FAU nurse-led team has collaborated with gatekeepers and stakeholders across the past 10 years to increase care of older adults in this region.

Study co-authors are Catherine Luna, Department of Psychology, Washington State University; Diane Cook, Ph.D., Regents Professor and Huie-Rogers Chair Professor, School of Electrical Engineering and Computer Science, Washington State University; Bryan D. Minor, Ph.D., associate in research, School of Electrical Engineering and Computer Science, Washington State University; and Marueen Schmitter-Edgecombe, Ph.D., Regents Professor, H.L. Eastlick Distinguished Professor, Department of Psychology, Washington State University.  

This research was supported by the National Institute on Aging of the National Institutes of Health under award number R35 AG071451, and by the National Science Foundation under award number 1954372.

- FAU -

About Florida Atlantic University:
Florida Atlantic University, established in 1961, officially opened its doors in 1964 as the fifth public university in Florida. Today, Florida Atlantic serves more than 30,000 undergraduate and graduate students across six campuses located along the Southeast Florida coast. In recent years, the University has doubled its research expenditures and outpaced its peers in student achievement rates. Through the coexistence of access and excellence, Florida Atlantic embodies an innovative model where traditional achievement gaps vanish. Florida Atlantic is designated as a Hispanic-serving institution, ranked as a top public university by U.S. News & World Report, and holds the designation of “R1: Very High Research Spending and Doctorate Production” by the Carnegie Classification of Institutions of Higher Education. Florida Atlantic shares this status with less than 5% of the nearly 4,000 universities in the United States. For more information, visit www.fau.edu.

 

Toxic environmental pollutants linked to faster aging and health risks in US adults



“Environmental chemical exposures represent a key modifiable risk factor impacting human health and longevity, and our findings provide evidence for associations between several environmental exposures and epigenetic aging in a large sample..."



Impact Journals LLC

Exposome-wide association study of environmental chemical exposures and epigenetic aging in the national health and nutrition examination survey 

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Figure 3. Volcano plots displaying the expected change in GrimAge acceleration for a 1 SD increase in log2-transformed exposure on the X-axis, and -log10 p-values on the Y-axis from the sensitivity models adjusting for cotinine exposure. Color corresponds to the broad category of exposure. Volcano plots for remaining epigenetic clocks are presented in Supplementary Figure 4.

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Credit: Copyright: © 2025 Khodasevich et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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BUFFALO, NY — March 5, 2025 — A new research paper was published in Aging (Aging-US) on February 11, 2025, Volume 17, Issue 2, titled “Exposome-wide association study of environmental chemical exposures and epigenetic aging in the national health and nutrition examination survey.”

First author Dennis Khodasevich and corresponding author Andres Cardenas from Stanford University, and colleagues from other U.S. institutions, studied how exposure to harmful chemicals in the environment affects aging. Using data from the National Health and Nutrition Examination Survey (NHANES), they discovered that cadmium, lead, and cotinine are linked to faster biological aging, a process that can increase the risk of age-related diseases.

The study analyzed data from 2,346 U.S. adults aged 50 to 84 who participated in a national health survey. Researchers tested their blood and urine for 64 different chemicals, including metals, pesticides, and industrial pollutants. They assessed how these exposures influenced eight different epigenetic aging markers—biological clocks that measure how fast a person’s body is aging at the DNA level.

“We harnessed data from the National Health and Nutrition Examination Survey 1999-2000 and 2001-2002 cycles to examine exposome-wide associations between environmental exposures and epigenetic aging.”

The strongest effects were linked to cadmium, a toxic metal found in cigarette smoke and some foods. People with higher levels of cadmium in their blood showed signs of accelerated aging. Higher levels of cotinine, a chemical related to tobacco exposure, were also linked to increased biological age, reinforcing the harmful effects of smoking. Additionally, lead exposure, a heavy metal found in old paint and contaminated water, was also associated with faster aging.

The researchers also found that some pollutants, including a type of PCB (PCB118) and a type of dioxin (HpCDD), were linked to slower biological aging. However, it is unclear if this fact is beneficial, as past research shows that slower aging in some cases can still be linked to health risks.

This study is one of the largest to investigate how pollution affects the aging process. Unlike previous research that focused on only a few chemicals, it examined a wide range of pollutants in a diverse group of people. The findings suggest that everyday exposure to toxic substances can speed up aging at the cellular level, increasing the risk of age-related diseases.

In summary, these findings raise concerns about how widespread environmental contaminants may accelerate aging and contribute to chronic diseases such as heart disease, cancer, and cognitive decline. Reducing exposure to toxic substances like cadmium and lead—found in cigarettes, polluted air, and contaminated food—could help slow biological aging and improve long-term health. These insights highlight the need for stronger environmental health policies to protect individuals from premature aging and disease.


Read the full paper: DOIhttps://doi.org/10.18632/aging.206201

Corresponding author: Andres Cardenas — andresca@stanford.edu

Keywords: aging, epigenetic aging, environmental exposures, exposome, epigenetics

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About Aging:

The journal Aging aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Aging is indexed by PubMed/Medline (abbreviated as “Aging (Albany NY)”), PubMed CentralWeb of Science: Science Citation Index Expanded (abbreviated as “Aging‐US” and listed in the Cell Biology and Geriatrics & Gerontology categories), Scopus (abbreviated as “Aging” and listed in the Cell Biology and Aging categories), Biological Abstracts, BIOSIS Previews, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science).

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Study reveals how agave plants survive extreme droughts

Researchers use terahertz spectroscopy to explore how agaves retain water in dry environments, offering insights for drought-resistant crops

Peer-Reviewed Publication

Optica

Agave plants 

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The researchers found that agave leaves have an inner core that remains highly hydrated while the outer layer acts as a protective barrier to reduce water loss.

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Credit: Enrique Castro, CIO

WASHINGTON — Agave plants may be best known for their role in tequila production, but they are also remarkably adept at retaining water in extremely dry environments. In a new study, researchers used terahertz spectroscopy and imaging to gain new insights into how these succulents store and manage water to survive in dry conditions.

“Understanding how plants adapt to dry conditions could lead to better farming practices and be used to develop crops that require less water,” said Monica Ortiz-Martinez from the Centro de Investigaciones en Optica (CIO) in Mexico. “This could lead to higher crop yields with lower water consumption, benefiting farmers, food production and global food security.”

The new study utilizes terahertz waves, which fall between microwaves and the mid-infrared region of the electromagnetic spectrum. Because water strongly absorbs terahertz radiation, the researchers used terahertz spectroscopy and imaging to measure hydration levels in plant tissues, map the water inside the plant and study how its fructan sugars hold onto water at a molecular level.

In the Optica Publishing Group journal Applied Optics, the researchers show that terahertz spectroscopy is a powerful tool for studying plants without causing any damage. Using this approach, they found that agave plants survive in dry environments by storing water in a specialized leaf structure and that its fructans act like molecular sponges to retain moisture.

“In the food industry, our findings on agave fructans and their exceptional water-binding properties could be used to develop new food ingredients that improve moisture retention, texture and shelf life, especially in dried or processed foods,” said the paper’s first author Enrique Castro-Camus from CIO. “This could lead to healthier, longer-lasting food products with fewer artificial preservatives.”

Combining biology and food science

The agave research began as a collaboration between the Applied Terahertz Science group at CIO with June Simpson at Centro de Investigaciones Avanzadas (CINVESTAV) to explore water distribution in agave leaves and its connection to fructans from a biological perspective. Around the same time, the CIO  group began a partnership with Socorro Villanueva from Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco (CIATEJ) that took a more food science approach to studying how fructans, which are used as food additives, form microscopic water layers that protect frozen products from freeze-related damage. Eventually, these two investigations came together to form a complete story of how agaves withstand extreme drought.

For terahertz imaging, the researchers used a time-domain terahertz spectrometer with a femtosecond fiber laser and sub-mm pixel resolution. They placed thin leaf slices between a terahertz emitter and detector and then used the water absorption measurements to map hydration levels. They reconfigured the same time-domain terahertz spectrometer to an attenuated total reflection geometry to analyze solutions containing fructan.

“Our research introduces several key innovations in the study of plant hydration using terahertz technology,” said Monica Ortiz-Martinez. “One of the most significant advancements is non-invasive water detection — unlike traditional methods that require cutting, drying and weighing plant samples, terahertz imaging enables real-time hydration analysis without damaging the plant.”

The analysis revealed that agave leaves have a specialized water storage system, where the leaf’s inner core remains highly hydrated while the outer layer acts as a protective barrier to reduce water loss. The researchers also found that fructans have an exceptional ability to attract and hold on to water molecules around them, far stronger than other sugars. This is because the branched chemical structure of fructans forms a kind of porous sponge on which water can be retained to keep the plant hydrated despite high temperatures.

The combination of tissue-level water storage and molecular-level water retention make agaves highly drought-resistant, enabling them to thrive in arid environments where water is scarce.

Expanding the technology

Next, the researchers plan to expand the use of terahertz spectroscopy and imaging to study drought resistance in a wider range of plant species. They want to investigate how different plants manage water at both the tissue and molecular levels, particularly crops that are essential for global food security.

The researchers say that with further development, the setup, which is currently optimized for laboratory use, could be made into a portable and cost-effective terahertz system that could be used in fields or greenhouses for monitoring. Combining this with advanced machine learning algorithms to analyze terahertz images more efficiently could enable real-time detection of hydration patterns and drought stress indicators.

The researchers emphasize that achieving results with meaningful social and economic impact requires strong interdisciplinary collaboration, with close cooperation between experts in optics, plant physiology and food science being key in this study.

“By advancing non-invasive plant monitoring methods, our research lays the foundation for smarter, more sustainable agricultural practices, ultimately benefiting both farmers and consumers while helping to conserve natural resources for future generations,” said Castro-Camus.

Paper: E. Castro-Camus, A. K. Singh, A. V. Perez-Lopez, J. A. Morales-Hernandez, J. Simpson, S. J. Villanueva-Rodriguez, M. Ortiz-Martinez, “Terahertz spectroscopy and imaging as a tool to unlock physiological and molecular mechanisms for drought resistance of agaves,” Applied Optics, 64, (2025).
DOI: https://doi.org/10.1364/AO.547952

About Optica Publishing Group

Optica Publishing Group is a division of the society, Optica, Advancing Optics and Photonics Worldwide. It publishes the largest collection of peer-reviewed and most-cited content in optics and photonics, including 18 prestigious journals, the society’s flagship member magazine, and papers and videos from more than 835 conferences. With over 400,000 journal articles, conference papers and videos to search, discover and access, our publications portfolio represents the full range of research in the field from around the globe.

About Applied Optics

Applied Optics publishes in-depth peer-reviewed content about applications-centered research in optics. These articles cover research in optical technology, photonics, lasers, information processing, sensing, and environmental optics. Optica Publishing Group publishes Applied Optics three times per month and oversees Editor-in-Chief Gisele Bennett, MEPSS LLC. For more information, visit Applied Optics.

Researchers used terahertz spectroscopy and imaging to better understand how agave plants (pictured) store and manage water to survive in dry conditions.

Credit

June Simpson, CINVESTAV

The analysis showed that fructans have a branched chemical structure that forms a kind of porous sponge on which water can be retained. This keeps the plant hydrated despite high temperatures. The illustration shows an Agave striata leaf and the molecular structure of its fructans, with water molecules bound around the fructan chains.

Credit

Monica Ortiz-Martinez, CIO

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mediarelations@optica.org

 

Cloud–radiation feedbacks found to be key to the diverse tropical pacific warming projections



Institute of Atmospheric Physics, Chinese Academy of Sciences
Sunset over the Strait of Malacca 

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The cover photo, taken at the Strait of Malacca in Malaysia, captures the Tyndall effect as sunlight filters through the clouds over the tropical Pacific. The interplay of light and shadow metaphorically illustrates how cloud feedback shapes ocean warming patterns, highlighting the critical role of cloud processes in modulating climate responses. 

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Credit: Photo credit: Yanfang Lin; Cover credit: Advances in Atmospheric Sciences




New research has uncovered why different climate models offer varying projections of sea surface temperature (SST) changes in the tropical Pacific, a region critical for global climate patterns. The study, published in Advances in Atmospheric Sciences on March 5, identifies cloud–radiation feedback as the dominant source behind these differences.

Reliable projections of the tropical Pacific SST warming (TPSW) pattern are crucial for understanding how global climate will change in a warming world. While the latest climate models from the Coupled Model Intercomparison Project Phase 6 (CMIP6) generally project an El Niño-like warming pattern—characterized by a weakening of the zonal SST gradient between the eastern and western tropical Pacific—the intensity of such weakening varies significantly across models.

Using advanced statistical techniques and heat budget analysis, researchers from China and the UK analyzed data from 30 CMIP6 models. They discovered that the diversity in projecting TPSW patterns stems from two distinct cloud–radiation feedbacks:

  • Eastern Pacific: Different cloud–radiation feedback over the eastern Pacific drive varying magnitudes of El Niño-like warming. This is the leading source of uncertainty in the projected TPSW among models, particularly in the far eastern equatorial Pacific.
  • Central Pacific: Different negative cloud–radiation feedback over the central Pacific, coupled with ocean–atmosphere interactions including the wind–evaporation–SST (WES) feedback and the Bjerknes feedback, determines the different warming in the western Pacific. Most models underestimate this negative feedback, resulting in projections of stronger warming in the western Pacific than the multi-model average.

“These findings highlight the critical role of cloud–radiation feedback in shaping how different climate models project future warming patterns in the tropical Pacific,” said Dr. Jun Ying, lead author of the study, from Second Institute of Oceanography, Ministry of Natural Resources, China. “Unraveling these mechanisms brings us closer to producing more reliable climate projections.”

The study warns that the underestimated negative cloud–radiation feedback in models could mean the real-world tropical Pacific in the future will exhibit even stronger El Niño-like warming than currently projected, which is associated with more severe climate extremes, such as intense storms and prolonged droughts, underscoring the importance of improving climate model projections.

“Previous studies have identified the 'pattern effect' as being important in modifying the magnitude of different climate feedbacks, but here we consider climate feedbacks as being important in shaping the patterns of SST change. Moreover, this is one of the first to consider low-cloud feedbacks as being important in shaping the patterns of SST change” said Prof. Matthew Collins, one of the corresponding authors, from the University of Exeter, UK.

A major challenge lies in reconciling the observed long-term SST trend, which suggests a La Niña-like warming (enhanced west-minus-east SST gradient), with the El Niño-like pattern projected by CMIP6 models. The research team aims to resolve this discrepancy in a next study.

“Our ultimate goal is to refine model projections of the tropical Pacific SST warming pattern, providing a more convincing basis for estimating future climate changes” Dr. Ying added.