Friday, June 13, 2025

 

BathMat clinical trial launches across NHS Trusts to ease staff workload and boost patient care



Clinical trial of inflatable patient repositioning pillow device begins




University of Bath

The BathMat inflatable prone repositioning device, being demonstrated with a healthy volunteer 

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The BathMat inflatable prone repositioning device, being demonstrated with a healthy volunteer

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Credit: University of Bath




University of Bath press release

BathMat trial launches across NHS Trusts to ease staff workload and boost patient care

Clinical trial of inflatable patient repositioning pillow device begins

Clinical trials of an innovative inflatable pillow designed to make moving intensive care unit (ICU) patients safer, faster, and less labour-intensive for NHS staff have begun in Bath.

Co-developed by researchers at the University of Bath and clinicians at the Royal United Hospitals Bath NHS Foundation Trust (RUH), and funded by the National Institute for Health and Care Research (NIHR), the Inflatable Prone Repositioning Device – known as the ‘BathMat’ – is a flat balloon-like pillow that can be inflated in sections, and is the first medical device of its kind.

The device was conceived to tackle a major challenge in ICUs: repositioning sedated, ventilated patients in the prone (face-down) position – often among the most critically ill – to avoid pressure injuries and improve oxygenation. Placed under a sedated patient it can gently lift their chest and hips, helping ward staff safely and quickly reposition their head and arms.

The assistance provided by the BathMat has the added benefit of reducing the number of staff needed to move a patient from five to two.

Dr Alexander Lunt, Senior Lecturer in Mechanical Engineering at the University of Bath and the project’s Principal Investigator, said: “Moving critically ill patients is a significant challenge on intensive care wards worldwide. We are pleased to be using our engineering expertise to work toward a better solution to the issue, and to further build our close partnership with our partners at our local NHS Trust, the RUH.”

Trials in four major hospitals

Clinical trials to evaluate the BathMat’s effectiveness began at the RUH in late May. The trials will expand to include Southmead Hospital (North Bristol NHS Trust), Wythenshawe Hospital (Manchester University NHS Foundation Trust), and Derriford Hospital (University Hospitals Plymouth NHS Trust) in the coming weeks.

Aiming to recruit 30 patients across four NHS ICU sites, the trials are backed by a 14-month funding award from the NIHR. Several key outcomes will be measured, including reductions in staff time required for repositioning patients treated lying on their front (prone), improvements in patient healthcare outcomes such as pressure sore prevention, device safety and cost-effectiveness.

Widespread Enthusiasm from Healthcare Staff

Training sessions across the trial sites were met with overwhelmingly positive feedback. Hundreds of ICU staff have now been trained, with many describing the BathMat as a “no brainer” innovation.

Dr Jerome Condry, Chief Investigator and Research Fellow at the Royal United Hospitals Bath NHS Foundation Trust, said: "We’re seeing real enthusiasm from ICU teams who recognise the potential our device has to making repositioning proned patients easier and safer for everyone involved. We aim to have a big impact on both patient safety and team wellbeing."

Dr Lunt added: "We've already had other trusts reach out asking how they can access the device as they see the value it brings immediately."

Commercialisation and Next Steps

With regulatory approvals in place, the team is now turning its attention to commercialisation. Interest from investors is growing, and efforts are underway to develop a pressure-sensing version of the device that will automatically detect and adjust for pressure hotspots in real time.

Once all trial data is collected and analysed by health economics and statistics experts at the University of Bath, the team will publish the results and begin scaling up to reach more NHS stakeholders and manufacturers. The route to market is being actively developed in partnership with the University’s innovation and research commercialisation teams.

Call for collaborators

The research team welcomes expressions of interest from other NHS trusts or international partners who wish to take part in future trials or demonstrations. Conferences and showcase events are scheduled for 2026 where preliminary results and the next-generation version of the BathMat will be unveiled.

For more information and media resources, visit bathmatmedical.com.

  

HeatiodThe 'BathMat' inflatable prone repositioning device

Credit

University of Bath

ENDS

 

Images and video are available at: https://tinyurl.com/yc4pczwm

For more information or to request interviews, contact:

Will McManus, University of Bath: wem25@bath.ac.uk / +44(0)1225 385 798

Matthew Smith, RUH: matthew.smith38@nhs.net

The University of Bath

The University of Bath is one of the UK's leading universities, with a reputation for high-impact research, excellence in education, student experience and graduate prospects. 

We are ranked in the top 10 of all of the UK’s major university guides. We are also ranked among the world’s top 10% of universities, placing 150th in the QS World University Rankings 2025. Bath was rated in the world’s top 10 universities for sport in the QS World University Rankings by Subject 2024.

Research from Bath is helping to change the world for the better. Across the University’s three Faculties and School of Management, our research is making an impact in society, leading to low-carbon living, positive digital futures, and improved health and wellbeing. Find out all about our Research with Impact: https://www.bath.ac.uk/campaigns/research-with-impact/

 

About the NIHR

The mission of the National Institute for Health and Care Research (NIHR) is to improve the health and wealth of the nation through research. We do this by:

  • Funding high quality, timely research that benefits the NHS, public health and social care;
  • Investing in world-class expertise, facilities and a skilled delivery workforce to translate discoveries into improved treatments and services;
  • Partnering with patients, service users, carers and communities, improving the relevance, quality and impact of our research;
  • Attracting, training and supporting the best researchers to tackle complex health and social care challenges;
  • Collaborating with other public funders, charities and industry to help shape a cohesive and globally competitive research system;
  • Funding applied global health research and training to meet the needs of the poorest people in low and middle income countries.

NIHR is funded by the Department of Health and Social Care. Its work in low and middle income countries is principally funded through UK international development funding from the UK government.

 

 

New study from landmark trial suggests avocados may play a role in sleep, a key factor in cardiovascular health



Hass Avocado Board
Heart-Healthy Grilled Shrimp Avocado Veggie Skewers 

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New research suggests that eating one avocado a day may positively impact sleep.

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Credit: Image courtesy of Avocados - Love One Today.




MISSION VIEJO, Calif. (June 11, 2025) – A new study suggests that eating one avocado a day may positively impact sleep. Science now confirms sleep is as important for good health as nutrition and exercise. In a secondary analysis of the largest randomized controlled trial on avocados to date, researchers found adults who consumed one avocado daily for six months reported better sleep compared to those who ate fewer than two avocados per month.

As, per the CDC, getting enough sleep can help lower the risk factors for heart disease, these findings add to a growing body of evidence supporting avocados as a heart-healthy food and mark the first time avocado consumption has been associated with sleep. The American Heart Association (AHA) recognizes healthy sleep duration as one of eight health factors that, when optimized, can promote ideal cardiovascular health.

“Sleep is emerging as a key lifestyle factor in heart health, and this study invites us to consider how nutrition—and foods like avocado—can play a role in improving it,” said Dr. Kristina Petersen, study author and associate professor of nutritional sciences at Penn State University. “Cardiovascular health is influenced by many factors, and while no single food is a silver bullet, some—like avocados—offer a range of nutrients that support multiple aspects of heart health. This is an encouraging step in expanding the science around avocados and the potential benefits of consumption.”

Supported by the Avocado Nutrition Center, this study involved 969 racially and ethnically diverse American adults with elevated waist circumference, a cardiovascular risk factor that affects nearly 60% of U.S. adults. Participants were randomized to either consume one avocado per day or minimal avocado intake (less than two avocados per month) while continuing their usual diet for six months.

Cardiovascular health was assessed using the AHA’s Life’s Essential 8TM, a framework used by healthcare professionals as well as individuals to better understand and reduce risk factors. This tool identifies diet quality, physical activity, nicotine exposure, sleep, body weight, blood pressure, blood lipids, and blood glucose as leading behaviors and factors that when improved, can lead to better health outcomes.  

Daily avocado intake was associated with improved diet quality (measured by the Healthy Eating Index 2015), blood lipids (modest reductions in LDL-C and total cholesterol levels) and sleep health (increased self-reported sleep duration). No significant effects were found for the other Life’s Essential 8 components.

Though the study was not originally designed to examine sleep as a primary outcome, the results offer an exciting direction for future research with more rigorous methodology and tools to better understand the potential for how the nutrients in avocados may support aspects of cardiovascular health. There are several strengths to this study design, but the findings are not conclusive and cannot be generalized to all populations.

Avocados have the following nutrients per serving (1/3 medium avocado) that may play a role in sleep:  

  • Tryptophan – 13mg, precursor to melatonin which plays a role in regulating sleep
  • Folate – 45 mcg (10% DV), involved in the production of melatonin  
  • Magnesium – 15mg (4% DV), involved in muscle contraction and relaxation 

Additionally, the combination of fiber and monounsaturated fats in avocados contributes to their beneficial impact on cardiovascular health.

  • Fiber – 3g (11% DV), one-third of the fiber in avocado is soluble fiber, which prevents the digestive tract from absorbing cholesterol and reduces the risk of heart disease
  • Monounsaturated fat – 5g, can help reduce LDL cholesterol levels, which can lower the risk of heart disease and stroke

To help healthcare providers and other experts encourage healthy dietary habits that incorporate avocado goodness and further the food is medicine movement, a free cookbook, Heart-Healthy Recipes Featuring Avocados, is available here.

About Avocados – Love One Today®

Avocados – Love One Today® is a leading source of the healthiest reasons and tastiest ways to enjoy fresh avocados. A science-based resource, it provides facts about fresh avocados in relevant and credible ways to help make it easy for health professionals and consumers to learn more about the nutritional benefits of fresh avocados and ways to include them in everyday menus. Visit www.LoveOneToday.com for avocado nutrition, recipes, and tips.

# # #

Media Contact

Vickie Fite

vickie.fite@mslgroup.com

310-264-6966

 

Same ecosystem, different fix


International research team shows nature restoration must be tailored to local conditions



University of Göttingen

Intact Mediterranean-type oak savanna (Tonzi Ranch), a research site of the University of California, Berke-ley, whose researchers contributed to the study 

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Intact Mediterranean-type oak savanna (Tonzi Ranch), a research site of the University of California, Berke-ley, whose researchers contributed to the study

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Credit: Sebastian Fiedler




As the world focuses on repairing damaged ecosystems, especially with the UN Decade on Ecosystem Restoration and new EU Nature Restoration law in place, a new study sounds a clear message: when it comes to restoring nature, one size doesn’t fit all. A team of scientists, led by the University of Göttingen and Freie Universität Berlin, found that even ecosystems that look similar on the surface can respond very differently to the same restoration methods. If we want to bring back nature in a way that helps absorb carbon, keep water in the ground, and recycle nutrients, policy makers need to think locally. The findings were published in the journal Ecography.

 

In 2019, researchers from around the world joined forces to study how to best restore dry, Mediterranean-style landscapes – places with wet winters and dry summers, like parts of the Mediterranean, California, Chile, South Africa, and Australia. These regions are under serious environmental stress and urgently need support. The team wanted to find out which combinations of native plants could best bring back the land’s natural functions. Because these ecosystems are so vast and varied, they built a computer model – which works like a strategy computer game for scientists – to test how different plant mixes would perform in different soils and climates.

 

The model matched up well with real-world results from a large restoration project in southwestern Australia. In addition, it showed that trying to achieve all goals at once – storing more carbon, saving water, and holding on to nitrogen – is tough. Compromises are often needed, and what works best depends a lot on local soil and climate conditions. “The great news is that this tool can help us choose the best plants for a local area, depending on what we want to achieve,” said Dr Sebastian Fiedler, Postdoctoral Researcher at Technische Universität Berlin, who led this research at Göttingen University and Freie Universität Berlin.

 

Fiedler continues: “But we’re not done yet – right now, the model doesn’t include things like wildfires, which are becoming more common and could change everything. That’s our next step.”

 

Original publication: Fiedler, S. et al. (2025). Trade-offs among restored ecosystem functions are context-dependent in Mediterranean-type regions. Ecography. DoI: 10.1002/ecog.07609

Restoration of Mediterranean-type woodland with protected young trees, Valencian Community, Spain – researchers from this region contributed to the study

Credit

Sebastian Fiedler

 Journal

 

UK Minister unveils first of its kind AI for Science Master's



The Minister for AI and Digital Government launched the UK’s first of its kind AI for Science Master’s programme at King’s College London.



King's College London




The Minister for AI and Digital Government launched the UK’s first of its kind AI for Science Master’s programme at King’s College London.

Feryal Clark MP joined leading King’s interdisciplinary scientists at the Quad to announce the new programme, which will draw expertise from across disciplines, including biosciences, humanities, social sciences, mathematics, security and law – preparing AI experts of the future in an ever-changing world.

The Master’s is part of King’s major £45.5 million investment into science – helping to tackle some of the biggest challenges facing us all. The investment is advancing knowledge, strengthening skills and powering exploration across the sciences, through education, research and state-of-the-art facilities.

AI and Digital Government Minister Feryal Clark said: “AI is transforming how we solve the world’s biggest challenges, and this new Master’s at King’s will create a generation of AI-minds ready to turn scientific ambition into real world solutions – just like the road that can mend its own cracks and assistive robot I saw today.

“Building this talent pipeline is central to our Plan for Change and builds on the £187 million we announced this week to give Brits the skills needed for the jobs of the future - investing in the talent and expertise that will keep us leading on AI and delivering for working people.” 

 

The visit was hosted by Vice-Chancellor & President of King's College London, Professor Shitij Kapur, and Minister Clark saw ongoing interdisciplinary AI research from the very experts who will deliver teaching for the new course and who are leading the digital revolution in science.

Vice-Chancellor & President of King's College London, Professor Shitij Kapur said: “We are delighted to welcome Minister Clark to King’s for the second time this year as we celebrate the launch of our new AI for Science MSc. King’s is at the forefront of interdisciplinary AI research and innovation, and this programme, the first of its kind, will help build a future pipeline of specialists fluent in both science and AI. Through our world-leading education and research at scale and across disciplines, we look forward to continuing to support the government to deliver on its bold ambitions for the future of AI – one that will support economic growth, nurture talent and improve lives in the UK.” 

 

Dr Dan Nicolau AI for Science Programme Lead, King’s College London, said: “The AI for Science programme is for science or maths graduates, seeking to be at the forefront of scientific discovery. It will provide a thorough grounding in AI techniques and applications for solving complex and real-world scientific challenges.

“The programme will help students to enter the dynamic, uncertain job market defined by the need to remain flexible and at the forefront of developments in AI technologies, which will alter the practice of these disciplines, industrially, academically and in the public sector.

“Students will become bilingual in science and AI, with a grasp of the very latest technical, as well as social, ethical and legislative developments, equipping them to thrive in the future as AI science natives."

At the launch, Dr Heba Sailem, Senior Lecturer of Biomedical AI and Data Science, shared how she is developing AI approaches to improve patient treatment and welfare – combining insights from histopathology, genetics, pharmaceutical medicine and cell biology.

Dr Francisco Martin-Marinez, senior lecturer in Chemistry, explained how he is combining AI and materials science to address the country’s £143 million pothole problem, developing a self-healing, sustainable road surface made from recycled oils.

Feryal Clark MP then received a demonstration of an assistive robot which is being programmed by researchers at King’s to help people live independently for longer, for example by helping people to feed themselves.

The announcement of the AI for Science Master’s follows a successful launch of a new Natural Sciences undergraduate course in 2024, which is in the top 10 in the UK for Natural Sciences (QS by subject 2025).

Professor Elena Simperl, King’s Institute for Artificial Intelligence Co-Director said: “This AI for Science Master's programme showcases what AI at King's is all about: world-class research and education focused on harnessing AI for the benefit of humanity. The King's Institute for Artificial Intelligence is a strategic King's-wide initiative to bring cohesion to the remarkable reach and impact of AI across the university. By developing a deeper pool of AI expertise and talent equipped to create, deploy and apply AI solutions, we’re ensuring AI serves society’s greatest challenges with the quality data and responsible frameworks needed to benefit everyone.” 

 

18 new academics have also joined the University to supercharge its science research and education, driving interdisciplinary research in wide ranging areas, from computational neuroscience to net zero.

Find out more about the AI for Science programme https://www.kcl.ac.uk/study/postgraduate-taught/courses/artificial-intelligence-for-science-msc  

 

 

Study finds ethical justification to eradicate certain harmful species




Texas A&M University




Under what conditions would it be right — or is it never acceptable — to eliminate a harmful species from our planet? That’s what an international team of researchers, including Professor of Philosophy Dr. Clare Palmer from Texas A&M University, explores in a study published in Science.

In the study, “Deliberate extinction by genome modification: An ethical challenge,” researchers examine the controversial idea of using genetic engineering for local and full species extinction as a conservation strategy. They conducted case studies on three species: the New World screwworm (Cochliomyia hominivorax); the Anopheles gambiae mosquito, a vector for malaria; and invasive rodent species like the house mouse and black rat.

“Together, we argue, these cases suggest that deliberate full extinction might occasionally be acceptable, but only extremely rarely,” the team states.

Screwworms, Mosquitos And Invasive Rodents

screwworm is a parasitic fly that infests warm-blooded animals, causing severe suffering and economic loss, particularly in livestock. Mosquitos carrying malaria are extremely dangerous for humans of all ages. Nearly 290 million people around the world are infected annually, and 400,000 of them will die of the disease.  And invasive house mice on islands are eating seabirds alive, driving their populations toward extinction.

“These cases highlight the tension between the intrinsic value of a species and the benefits of eradicating a harmful pest,” Palmer said. “While the suffering caused by these species is undeniable, the ethical implications of deliberately driving a species to extinction are profound. We must carefully weigh the ecological and moral implications of such actions.”

Genome Modification For Extinction

The researchers examined the use of several genetic methods to eradicate harmful species:

  • Sterile Insect Technique (SIT): Mass-reared insects are exposed to radiation to produce sterilizing genetic mutations. These sterilized insects are then released in large numbers with the goal that sterile males mate with wild-type female insects, preventing reproduction. This method has been used to eradicate the New World screwworm locally in North and Central America and some Caribbean islands.
  • Female-Specific Release of Insects with a Dominant Lethal (fsRIDL): Genetically-modified male insects are released, and their offspring inherit a gene that kills female larvae unless they are exposed to a specific substance (like tetracycline). This reduces the population over time.
  • This method could be coupled with a Gene Drive that would push rapidly through a population, ensuring that nearly all offspring inherit the modification. This can lead to population suppression or full extinction; this method has been proposed to eradicate species like New World screwworm or Anopheles gambiae mosquitoes
  • Sex-Biasing Gene Drives: This genetic modification biases the sex ratio of a population, leading to a population crash. It is proposed for local eradication of house mice, black rats and Norway rats in places where the invasive species threaten native species, such as islands where they pose a threat to endangered birds. However, this technology might escape confinement and risks fullextinction of the targeted species.

Factors For Ethical Justification

The researchers conclude that while deliberate extinction through genome modification is justified in rare and compelling cases, it should be approached with caution. The study calls for robust ethical safeguards and inclusive decision-making frameworks to guide the use of these powerful technologies.

They suggest the following conditions under which eradication could be considered:

  • Severity of Suffering: The species causes extreme suffering and death to human beings or other animals that can’t otherwise be prevented.
  • Ecological Impact: The species threatens the continuance of other species, is not itself ecologically vital, and its eradication does not have substantial negative environmental impacts.
  • Effectiveness of Existing Methods: Genomic strategies should offer a more effective solution than traditional methods.
  • Risk of Unintended Consequences: The risk of unintended consequences, in particular the inadvertent full extinction of the species where this is not intended, should be negligible.
  • Public Health and Welfare Threat: The species poses a significant public health threat or brings major negative impacts to food security.
  • Ethical Considerations: Even taking the intrinsic value of the species and any environmental benefits it confers seriously, these can be argued to be outweighed by the harm it causes.
  • Inclusive Governance: Involving local communities and stakeholders in decision-making is essential to ensure that diverse perspectives are heard, and that those who are most affected are equitably represented.

Palmer said she hopes the study will influence public policy and conservation practices. “Our goal is to foster a more nuanced understanding of the ethical dimensions of genome modification,” she said. “We need to balance the potential benefits with the moral responsibilities we have towards all species.”

This research was funded by a grant from the National Science Foundation.

By Lesley Henton, Texas A&M University Division of Marketing and Communications

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