We can help the body fight entire viral families

LJI scientists discover how we can harness T cells to combat deadly infections, including Lassa fever and hantavirus disease

La Jolla Institute for Immunology

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LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have discovered that combining key vaccine ingredients could give the body the tools it needs to fight the entire family of arenaviruses with a single vaccine. This “pan-arenavirus” vaccine approach may protect against life-threatening infections from Lassa virus, Junin virus, and many other arenaviruses with pandemic potential.

"We are now moving toward the next steps of designing vaccines and seeing which formulations may work best," says LJI Professor Alessandro Sette, Dr.Bio.Sci.

This research comes as scientists are working to stop the spread of Andes hantavirus, which recently caused a deadly outbreak among cruise ship passengers and crewmembers. Hantaviruses and arenaviruses are very similar in how they spread (between rodents and humans) and how they work (both are single-strand, segmented RNA viruses). 

In their Cell Reports Medicine paper, the researchers show that T cells can spot the family resemblance between different species of arenaviruses. Harnessing these "cross-reactive" T cells is critical for designing "pan-viral" vaccines that combat many viruses at once.

"We can apply this new research approach to multiple viral families, no matter how rare they are in the human population," says LJI Research Assistant Professor Alba Grifoni, Ph.D., who co-led the study, with funding from the National Institutes of Health and the Coalition for Epidemic Preparedness Innovations (CEPI).

Investigating a dangerous viral family

Arenaviruses are most common in West Africa countries, where the deadliest arenavirus is called Lassa virus. This virus is spread by a species of rodent, called the multimammate rat. 

Lassa virus kills by causing severe, flu-like symptoms, which can lead to bleeding from the mouth or gastrointestinal tract. The virus kills between 5,000 and 10,000 people each year and hospitalizes many more.

And Lassa virus has several dangerous relatives. The arenavirus family is known for its pandemic potential. Eight arenavirus species are known to cause disease in humans, and there are dozens of other arenaviruses that spread in animal populations.

About 45,000 years ago, arenavirus evolution diverged, leading to marked differences between "Old World" arenaviruses (in European, African, and Asian countries) and "New World" arenaviruses (in the Americas).

For the new study, LJI scientists examined whether T cells could "cross-react" between Old World and New World arenavirus species. After thousands of years, could T cells still spot the family resemblance?

Answering this question is key to pandemic preparedness. 

"Animals carry many viruses, and only some of these viruses will acquire the ability to infect humans and cause an outbreak," says Grifoni. "It's hard to predict which emerging virus might cause disease, which is why it is important to study T cells. "So why do we want to look at T cells? T cells are good at recognizing viruses, even if a virus is mutating."

Taking on Old World arenaviruses

First came an encouraging discovery—the scientists found that human T cells have the ability to cross-react to epitopes shared by all Old World arenavirus species. Epitopes are sites on a virus that T cells can recognize as a sign of infection. Sette and Grifoni found that Old World arenaviruses have shared, or "conserved," epitopes.

That means a vaccine against Lassa virus could potentially also protect against the Old World Lujo virus and lymphocytic choriomeningitis virus (LCMV) for example. In fact, there are already experimental Lassa virus vaccines under development that can induce T cells able to target these shared epitopes that are similar within the Old world viral family.

T cells that targeted Old World arenaviruses did not cross-react to New World arenaviruses. It appears the two groups of viruses are too different and don't share the same epitopes.

New World, new epitopes

It was time to learn more about New World arenavirus epitopes. The scientists began by analyzing T cell responses to Junin virus, an arenavirus that causes Argentine hemorrhagic fever. Some people in Argentina have received a vaccine against Junin virus, which means their bodies have already produced T cells to fight infection. 

In work spearheaded by LJI Postdoctoral Associate YeiI Lee, Ph.D., the scientists discovered that certain T cells that target Junin can cross-react to other New World arenaviruses.

This discovery gives LJI researchers a potential path for developing a broad, "pan-arenavirus" vaccine. Every vaccine includes an immunogen, an ingredient such as a protein or peptide that sparks an immune response against a vulnerable piece of a pathogen. The new study suggests that a future vaccine should include two immunogens: one from an Old World arenavirus and one from a New World arenavirus.

By combining this virus-fighting weaponry, scientists could develop a vaccine that directs T cells to fight every type of infective arenavirus we know of. This broad T cell activity might even help us fight arenaviruses that emerge from animal reservoirs in the future.

Responding to hantaviruses

Lassa virus and Junin virus aren't part of daily life here in the United States—but hantaviruses are becoming more and more of a local concern. Hantavirus is carried by rodents here in California. According to the California Department of Public Health, risk of infection is low, but people should take steps to avoid rodent dropping and contaminated areas.

Recently, attention has turned to the risk of person-to-person hantavirus transmission. In May 2026, an outbreak of the Andes strain of hantavirus sickened 14 and killed three people on an international cruise ship.

Like arenaviruses, hantaviruses are primarily spread by rodents. The Andes hantavirus, which recently spread on the cruise ship MV Hondius, appears to have the unique ability to spread from human to human. 

Also like arenaviruses, hantaviruses are split into Old World and New World species. Importantly, both arenaviruses and hantaviruses are known as single-strand, segmented RNA viruses, which means they carry similar genetic instructions.

Sette says the new study shows how scientists can analyze T cells to devise life-saving vaccine strategies against arenaviruses, hantaviruses, paramyxoviruses (such as measles), togaviruses (such as Chikungunya), and many other threats.

The Sette and Grifoni labs have received important funding from the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) and from the Coalition for Epidemic Preparedness (CEPI) to lead research toward pandemic preparedness. Each study brings the LJI team closer to developing rapid response tools to analyze viruses and combat future outbreaks.

"LJI is chipping away and generating data for many different viral families of concern," says Sette. "This research lays the foundation for future studies when one might, God forbid, have to move quickly."

Authors of the study, "Decoding the Human CD4+ T cell Epitope Repertoire For Lassa Fever Virus Reveals Novel Pan-mammarenavirus Vaccine Candidates," included Leila Siddiqui, Alison Tarke, Margaret Kim, Tanner Michaelis, Mariah Macias, Elizabeth Phillips, Simon Mallal, Raphael Trevizani, April Frazier, Richard H Scheuermann, Abril Zuniga, Christian Zmasek, Kevin Spurgers, Gideon Akintunde, Spencer W. Stonier, Talita Bianca Gagliardi, Kelly Warfield, Haoyang Li, Kathryn M. Hastie, Erica Ollmann Saphire, and Gene S Tan.

This study was supported by the National Institute of Allergy and Infectious Diseases and the Intramural Research Program, both of the National Institutes of Health, under awards number 75N93024C00056, U19 AI142790, and R21 AI180853; and by CEPI through the CEPI Immunogen Design for Disease X program.

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Journal

Cell Reports Medicine

DOI

10.1016/j.xcrm.2026.102824 

Method of Research

Experimental study

Subject of Research

Cells

Article Title

Decoding the human CD4+ T cell epitope repertoire for Lassa fever virus reveals T-cell based pan-mammarenavirus vaccine candidates

Article Publication Date

19-May-2026

 

Reusable catheters a safe choice that could save NHS millions, study finds

University of Southampton

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Reusable catheter patients used 35 per cent fewer antibiotics compared to their single-use only counterparts

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Credit: University of Southampton

Reusable catheters are just as safe for patients as single-use ones and do not increase the risk of urinary tract infections, a new study has found.

Thousands of people use the devices to empty their bladders as much as four times a day on average, and the plastic tubes are used just once before being discarded.

Researchers from the University of Southampton followed hundreds of patients for a year to measure the health impact of reusable intermittent urinary catheters against single-use ones.

They discovered that those who tested reusable catheters used 35 per cent fewer antibiotics compared to their single-use only counterparts.

The landmark study, published in the International Journal of Nursing Studies, was funded by the National Institute for Health and Care Research (NIHR).

Experts say the findings could save the NHS millions and cut down on thousands of tonnes of plastic waste produced each year.

Lead author Professor Mandy Fader, in the school of Health Sciences at the University of Southampton, said: “Until now, there has been a real lack of high-quality evidence to support the reuse of catheters.

“But, with our study, we can say for the first time that it is a safe option to switch to reusable catheters.”

For decades, patients in the UK have been strictly advised by healthcare professionals to use single-use catheters to prevent urinary tract infections (UTIs), leaving no choice for those wanting to use the more green-friendly reusable options.

The Southampton study followed 578 participants across a 12-month period, split into two groups – one of which stuck to single-use tubes.

The other group, however, used both the reusable and single-use catheters, and were given a kit to wash them in soap and water, followed by a soak in chlorine solution.

Scientists found 29 per cent of those in the mixed-use group had at least one UTI during the year, compared to about 34 per cent of those who used a fresh one each time.

Study co-author Margaret Macaulay, also from Southampton, said: “The NHS is full of single-use products, and many healthcare professionals caution against reusable items because of the risk of infection.

“However, our results clearly show that reusable catheters can and should be used by the NHS without increasing infection rates.

“People should have the choice to switch depending on their lifestyle needs – and cut down on the throwaway culture in our health service.”

According to the research team, around 100 million single-use catheters are prescribed by the NHS across the UK every year.

They also found that cost of the single-use tubes to taxpayers has risen from £22million in 1998 to around £200million in 2026.

“A box of 30 single-use catheters can cost about £50,” added Southampton Professor of Continence Cathy Murphy.

“Reusable catheters in our trial cost less than 10p per use and can be reused for a month. If just 25 per cent of patients made the switch, the NHS could save millions.”

Professor Marian Knight, NIHR Programme Director of Programme Grants for Applied Research said: "This study is a powerful example of how NIHR-funded research could lead to real-world impact, improving patient choice, saving the NHS millions, and reducing plastic waste.

“These findings will give the NHS the evidence it needs to consider introducing reusable catheters.

“It shows that thousands of people who use catheters every day could choose reusable catheters without concern about an increased risk of infection compared with single-use options, giving patients access to a more environmentally friendly choice."

ENDS
579 WORDS

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Journal

International Journal of Nursing Studies

DOI

10.1016/j.ijnurstu.2026.105536 

Method of Research

Meta-analysis

Subject of Research

People

Article Title

A non-inferiority randomised controlled trial to compare mixed (multi/single-use) catheter management with single-use catheter management by intermittent catheter users over 12 months

Article Publication Date

21-May-2026

 

Common food preservatives linked to high blood pressure and heart disease

European Society of Cardiology

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Illustration: Common food preservatives linked to high blood pressure and heart disease

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Credit: Mathilde Touvier

 

• The study of 112,395 people includes detailed analysis of diet and food ingredients.

• Researchers found eight preservative food additives linked to high blood pressure or cardiovascular disease.

• The highest risks were in people who ate the most preservatives.

 

Sophia Antipolis, France – 21 May 2026. Eating foods that contain common preservative food additives may increase the risks of high blood pressure and cardiovascular disease, according to research published in the European Heart Journal [1] today (Thursday).

 

The research was led by Dr Mathilde Touvier, a research director at INSERM (the French National Institute for Health and Medical Research), and Anaïs Hasenböhler, PhD student, both from the Nutritional Epidemiology Research Team at the Université Sorbonne Paris Nord and Université Paris Cité, France.

 

Ms Hasenböhler said: “Food preservatives are used in hundreds of thousands of industrially processed foods. Experimental studies suggest that some preservative food additives may be harmful to cardiovascular health, but we have not had enough evidence on the impact of these ingredients in humans. As far as we know, this is the first study of its kind to investigate the links between a wide range of preservatives and cardiovascular health.”

 

The research is part of a larger study, called NutriNet-Santé, and included 112,395 volunteers from across France. Every six months the volunteers told researchers everything they ate and drank over a period of three days.

 

Researchers carried out detailed analyses of the ingredients of all the food and drink, including any preservatives. They also tracked the volunteers’ health for an average of seven to eight years to see if they develop high blood pressure or any cardiovascular disease.

 

Researcher found that 99.5% of the volunteers had consumed at least one food preservative within the first two years of taking part.

 

Overall, they found that people who ate the largest amounts of ‘non-antioxidant’ preservatives had a 29% higher risk of hypertension, compared to those who ate the least, and a 16% higher risk of cardiovascular disease, including heart attack, stroke and angina. People who ate the most antioxidant preservatives had a 22% higher risk of hypertension. Non-antioxidant preservatives are designed to stop harmful microbes, such as mould and bacteria, from growing, whereas antioxidant preservatives are designed to stop oxidation which means the food will not turn brown or become rancid.

 

Researchers also looked at 17 of the most commonly eaten preservatives and found that eight of these were specifically linked to high blood pressure. These were: potassium sorbate (E202), potassium metabisulphite (E224), sodium nitrite (E250), ascorbic acid (E300), sodium ascorbate (E301), sodium erythorbate (E316), citric acid (E330) and extracts of rosemary (E392). Ascorbic acid (E300) was also specifically linked to cardiovascular disease.

 

Dr Touvier added: “This study has some limitations inherent to its observational design. However, the findings are based on highly detailed data, and we have taken account of other factors that can increase or lower the risk of cardiovascular disease. Experimental research in the literature consistently suggested that preservatives may cause oxidative stress in the body or affect the way the pancreas works.

These results suggest we need a re-evaluation of the risks and benefits of these food additives by the authorities in charge, such as the EFSA in Europe and the FDA in the USA, for better consumer protection. In the meantime, these findings support existing recommendations to favour non-processed and minimally processed foods, and avoid unnecessary additives. Doctors and other healthcare professionals play a key role in explaining these recommendations to the public.”

 

The researchers are now looking at how food additives and ultra-processed foods may affect signs of inflammation, oxidative stress, metabolic profile in the blood and the composition of the gut microbiota. This may help them to understand why additives may increase the risks of disease.

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Journal

European Heart Journal

DOI

10.1093/eurheartj/ehag308 

Method of Research

Observational study

Subject of Research

People

Article Title

Preservative food additives, hypertension, and cardiovascular diseases: the NutriNet-Santé study

 

SKKU research team awakens “hidden oxygen” to produce green hydrogen… pioneering next-generation water-splitting catalyst technology

Activates a novel reaction pathway by narrowing atomic spacing to the 0.1-angstrom (Å) level… Breaking away from reliance on expensive precious metals

Sungkyunkwan University External Affairs Division (PR team)

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A joint research team led by Professor Hyung Mo Jeong from the School of Mechanical Engineering at Sungkyunkwan University (SKKU) and Professor Ji Hoon Lee from the School of Materials Science and Engineering at Kyungpook National University has developed a highly efficient, non-precious metal water-splitting catalyst. By precisely controlling the bond spacing at the atomic level, the team successfully engaged the “lattice oxygen” hidden deep within the material to participate directly in the chemical reaction.

Water electrolysis, the process of splitting water to produce pure hydrogen without emitting greenhouse gases, is considered a dream technology for achieving carbon neutrality. However, the oxygen evolution reaction (OER) that occurs during this process is inherently sluggish. This slow reaction rate acts as a major “bottleneck” that degrades the overall efficiency of hydrogen production. To solve this, conventional systems have heavily relied on expensive precious metal catalysts such as iridium (Ir) or ruthenium (Ru), which significantly increases production costs.

To overcome these limitations, the joint research team introduced a “top-down materials design strategy.” Using electrochemical methods, the researchers successfully fragmented conventional bulk cobalt oxide into ultra-fine nanoclusters measuring under 2 nanometers (nm). During this process, they finely adjusted the atomic bond length between the cobalt metal and oxygen atoms, contracting it by approximately 0.1 angstroms (Å, one ten-billionth of a meter). High-performance structural analyses at the Pohang Accelerator Laboratory (PAL) verified for the first time globally that an engineered bond length of 2.03 Å is the optimal condition for inducing an entirely new reaction pathway.

The core of this technology lies in strengthening the metal-oxygen interactions, forcing the “lattice oxygen”—which typically remains inert within the catalyst’s internal structure—to actively engage in the reaction. The newly developed nanocatalyst demonstrated outstanding performance, operating at a lower energy level than expensive commercial Ir catalysts. Furthermore, when applied to actual systems, it proved its robust durability by operating for over 100 hours under high-current conditions without degradation, and also demonstrated excellent charging stability in next-generation zinc-air batteries.

Professor Hyung Mo Jeong explained, “The key point of this research is that we demonstrated the ability to completely alter the catalytic reaction pathway itself by finely controlling the bond distance at the atomic level. Beyond replacing cost-prohibitive precious metals for high-efficiency green hydrogen production, this technology will serve as a crucial benchmark for accelerating the commercialization of various next-generation eco-friendly energy devices.”

This research was supported by the Ministry of Science and ICT and the National Research Foundation of Korea. The groundbreaking results were published in Applied Catalysis B: Environment and Energy, a top-tier international journal in the environmental and energy material sciences.

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Journal

Applied Catalysis

DOI

10.1016/j.apcatb.2026.126857 

Article Title

The role of chemical bond contraction induced via nanoclusterization of cobalt oxide triggering robust lattice oxygen mechanism during the oxygen evolution reaction

 

Is listening to music while studying a helpful habit or hidden distraction?

New research from Edith Cowan University (ECU) has shed light on why so many students listen to background music while studying, and whether it helps or hinders their focus

Edith Cowan University

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21 May 2026 

New research from Edith Cowan University (ECU) has shed light on why so many students listen to background music while studying, and whether it helps or hinders their focus. 

The study, led by Dr Lindsey Cooke, surveyed more than 220 university students about whether they listen to music while reading for studying purposes.  

The findings suggest that the impact of music on study performance is not universal and instead shaped by individual differences in how people engage with music. 

More than half of the students (54 per cent) reported regularly listening to music when reading for study, while 46 per cent preferred silence.  

Among those who listened to music, almost all believed it helped their reading. 

Students described using music to boost motivation, enhance focus, or block out external noise, with Classical and Rock emerging as the most common genres. Many preferred non‑lyrical, slow music to support concentration. 

“Many students feel music helps them get into the zone, especially when they’re studying in noisy or distracting environments,” Dr Cooke said. 

Dr Cooke said the findings challenge long‑held assumptions about the cognitive impact of music during study. 

“There’s a widespread belief that music automatically drains cognitive resources, but our data shows the story is far more individual,” she said. 

The study found that a student’s working memory capacity or tendency to mind wander (daydream) did not influence whether they chose to listen to music or how distracted they felt by it.  

Instead, a student’s music engagement, i.e. how personally involved and emotionally connected they are with music, was strongly linked to whether they perceived background music as helpful and whether they chose to use it while studying. 

Dr Cooke said this highlights the importance of personal preference in study environments. 

“For some students, music genuinely supports their reading experience. For others, it gets in the way. The key is understanding your own relationship with music rather than assuming one-size-fits-all advice,” she said. 

The next phase of Dr Cooke’s research will test students’ actual reading comprehension when listening to different types of music, not just perceptions. 

The study ‘Music as a distraction during reading: Music listening habits of university students’ is published in the journal Psychology of Music. ECU authors Lindsey Cooke, Ross Hollett & Craig Speelman. 

- ends - 

 

Tori Pree, Senior Media Adviser (08) 6304 2208, t.pree@ecu.edu.au 

or   

ECU Public Relations, (08) 6304 2222, pr@ecu.edu.au  

 

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Journal

Psychology of Music

DOI

10.1177/030573562614212 

Method of Research

Survey

Subject of Research

People

Article Title

Music as a distraction during reading: Music listening habits of university students

 

The Lancet MedZero: a single platform for carbon data across every product in healthcare

National University of Singapore, Yong Loo Lin School of Medicine

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The Lancet MedZero team photo

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Credit: NUS Yong Loo Lin School of Medicine

If healthcare was a country, it would be the fifth largest carbon emitter on the planet – between the European Union and the Russian Federation, with CO2 emissions in the sector higher than all of aviation and shipping combined.

Yet, until today, carbon data has been available for less than 1% of the products a clinician or a health system uses each day.

The Lancet MedZero is built to close that gap. Launching today at the 79th World Health Assembly, the platform (www.medzerocarbon.com) is the first to provide comprehensive carbon analytics across the full spectrum of healthcare, from pharmaceuticals and surgical instruments to chest X-rays and blood tests.

Convened by The Lancet and developed by an international academic consortium, it has been designed by clinicians, for clinicians, with over 14,000 entries at launch.

The platform is built to inform decisions at every level of the health system with the aim of helping hospitals and clinics save money, reduce waste, improve patient care, and tackle climate change. For example:[1]

• A health policymaker in the UK could identify that a simple switch from polluting incineration to recycling would avoid over 311,000 tonnes of CO2e (the equivalent to taking 212,000 British cars off the road), saving 76 million GBP each year as a result.
• A hospital CEO in Singapore, can see transitioning to reusable surgical gowns would reduce CO2e emissions by 4,407 tonnes (equivalent to the annual electricity use of 3,159 HDB households in Singapore), saving around 700,000 SGD annually.
• And national procurement experts across the world can compare logistics alternatives, saving over 3.85 million tonnes of CO2e by shifting to lower-carbon freight options for pharmaceuticals, such as shipping, globally (equivalent to nearly twice the national emissions of Malta).

The platform’s launch at the World Health Assembly brought together the Editor in Chief of The Lancet, the Minister of Health of the Philippines, the International Medical Secretary for Doctors Without Borders, the UK NHS’s Chief Sustainability Officer, and the Permanent Secretary of the Thailand Ministry of Public Health.

“The climate crisis is a health crisis. But climate action depends on credible data.” Dr Richard Horton, Editor-in-Chief of The Lancet, said ahead of the launch, “The Lancet MedZero plans to create a shared global infrastructure of knowledge about the carbon footprint of health systems. Measurement is the foundation of accountability, and accountability is the motivation for action.”

 

 

The problem the Lancet MedZero solves

More than 100 countries, covering over half the world’s population, have now committed to tackling climate change through a WHO-led Alliance for Transformative Action on Climate and Health.

Until now, that data has been fragmented and inaccessible. The Lancet MedZero was built to change that.

For their hospitals and health systems to turn those commitments into action, they need transparent and trustworthy data to make evidence-based decisions. A surgeon redesigning a care pathway, a pharmacist restocking a hospital supply, a procurement lead renegotiating supply contracts, and a health minister setting national strategy: all of them need product-level carbon data, quickly and reliably.

 

A global collaboration built for scale

The Lancet MedZero is a global collaboration of clinicians, engineers, data scientists, economists, and public health professionals working to support healthcare decarbonisation worldwide. Convened by The Lancet, it brings together expertise in healthcare delivery, carbon analytics, and system transformation, with contributors from across Asia-Pacific, Europe, and North America. This diversity reflects a shared commitment to advancing sustainable healthcare across regions.

 

Academic partners: Health Intervention and Technology Assessment Program (HITAP), Thailand; National Institute for Environmental Studies (NIES), Japan; National University of Singapore; Northeastern University, USA; University of Birmingham, UK; University of Melbourne, Australia

About The Lancet: The Lancet is one of the world’s leading medical journals, published since 1823. It has a long-standing commitment to climate and health, including through the Lancet Countdown, the Lancet Commission on Sustainable Healthcare, and multiple commissions on planetary health, pollution, among others.

 

NUS Specific Quote
 

“Singapore’s health system is well-positioned to lead on sustainable healthcare in Asia. The Lancet MedZero gives us the data infrastructure to move from aspiration to action – making it possible for our hospitals and clinicians to make every procurement decision, every care pathway choice, with the climate in mind.”

Professor Nick Watts, Director, Centre for Sustainable Medicine, National University of Singapore (NUS)

How NUS contributes to the platform

 

The National University of Singapore (NUS), through its Centre for Sustainable Medicine (CoSM), is an academic partner of the Lancet MedZero and contributes to the platform in several concrete ways:
 

• Carbon analytics and life cycle data: CoSM researchers contribute primary life cycle assessment (LCA) data for medical products and healthcare services, quantifying the carbon impact of everything from how a product is manufactured to how it is used and disposed of in a clinical setting.
• Estimating carbon footprints at scale: CoSM also leads the development of the platform's models for the parts of a product's carbon footprint that are shared across many products - such as how it is shipped, used, and disposed of. This includes building practical methods to estimate the weight of tens of thousands of medical products (since weight drives much of the carbon cost of transport and waste). Together, these methods allow the platform to generate carbon estimates at a scale that would not be possible through manual data collection alone.
• Clinical translation and governance: CoSM provides clinical and technical oversight to ensure the platform’s decision-support tools are meaningful and actionable for frontline clinicians, hospital administrators, and policymakers in Singapore and globally.
   

How the Lancet MedZero benefits Singapore’s healthcare system

 

Singapore has committed to achieving net-zero emissions for its healthcare sector by 2050, in alignment with the Singapore Green Plan 2030, and has developed a baseline of its healthcare emissions as a foundation for action. The Lancet MedZero directly supports this ambition by giving Singapore’s health institutions access to verified, product-level carbon data that can inform:
 

• Public hospital procurement decisions – enabling MOH and cluster hospitals (NUHS, SingHealth, NHG Health) to choose lower-carbon products without compromising clinical quality or cost-effectiveness.
• National sustainability reporting – supporting the MOH in tracking and disclosing scope 3 healthcare emissions as part of Singapore’s international climate commitments.
• Clinical care pathway redesign – giving clinicians at public and private institutions access to evidence that supports lower-carbon, cost-saving alternatives in surgical, pharmaceutical, and diagnostic workflows.
   

As noted in the press release, a hospital CEO in Singapore can already use the platform to model, for example, how transitioning to reusable surgical gowns would reduce CO2e emissions by 4,407 tonnes and save approximately 700,000 SGD annually – equivalent to the annual electricity consumption of over 3,000 HDB households.

 

Next steps for Singapore

 

Following the platform’s launch at the 79th World Health Assembly, NUS will:
 

• Continue engaging with key institutional stakeholders and users including hospital leadership, MOH representatives, and the healthcare industry, to present the platform and identify priority use cases for local adoption.
• Pilot the platform with the clusters and healthcare institutions to validate the data in Singapore’s clinical and procurement context and generate locally relevant case studies.
• Engage academic and industry partners across Singapore to contribute data, expertise, and funding to sustain and grow the platform.

 

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[1] Carbon analytics, volume, and cost data drawn for each of the three examples from www.medzerocarbon.com and underlying data sources.