Monday, June 15, 2026

 

Scientist creates ‘mini‑universe’ to measure time without a clock




University of Birmingham

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Part of the apparatus to trap and cool rubidium atoms close to absolute zero  (~-273.15 degrees Celsius).  

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Credit: University of Birmingham






Images available here.  

 

New experiment provides powerful testbed for ideas in quantum cosmology and gravity - theories relating to the early universe can now be tested in the laboratory. 

 

A University of Birmingham scientist has built a 'mini universe' that takes a step towards answering one of science’s biggest questions: ‘what is time?’ 

Publishing his findings today in Physical Review Research, Professor Giovanni Barontini shows how it is possible to measure the flow of time without using a clock at all. The new findings provide a scientific model where a version of time emerges from the experiment itself. 

Some theories of physics, such as the Wheeler–DeWitt equation suggest that, at its deepest level, the universe has no built‑in time, but exists as a single, unchanging quantum state where particles exhibit both wave-like and particle-like properties. It treats the universe as a whole with no external clock, and any sense of time must emerge from internal relationships between parts. 

Professor Barontini used a cloud of 24,000 ultracold atoms - just a few billionths of a degree above absolute zero - to create a hermetically sealed quantum system that mimics a simple ‘universe’. The particles were trapped and divided with a thin barrier formed with two laser beams of different frequency to create an observed (‘bright’) and an unobserved (‘dark’) region. 

The ‘bright’ sector repeatedly expands and collapses, experiencing something like a Big Bang and a Big Crunch - a hypothetical scenario where the expansion of the cosmos eventually reverses. The experiment allows the sequence of events to be reconstructed from within the mini universe itself, without any reference to an external laboratory clock. 

The experiment demonstrated that time could emerge from changes happening inside a quantum system, rather than existing as something external that ticks along independently.  

Using the ‘mini universe’ demonstrated that ‘time’ could be created from the disorder or spread (entropy) of atoms and how they behaved in a system. Atoms could move between ‘bright’ and ‘dark’ regions, but the system was otherwise isolated from the outside world.  

When the spread of particles in the bright sector increased or decreased as atoms moved in or out, the system was ‘moving forward in time’. When this distribution of atoms did not change, time effectively stopped. Professor Barontini called this process ‘entropic time’, after finding that this version of time: 

  • Flows in one consistent direction, giving a clear ‘arrow of time’ 

  • Correctly orders events, even in a system expanding and contracting like a mini cosmos 

  • Speeds up or slows down depending on how entropy moves around 

Professor Barontini said: “In some theories of the universe, especially quantum gravity, time doesn’t appear as a built‑in feature. Yet in everyday life, time flows from past to future – why is this so, when most basic laws of physics work the same way forwards and backwards?  

“This study provides the first controlled experimental evidence that ‘time’ can be defined by changes within a system rather than as the external ‘ticking clock’ we think of as time. It offers new insight into the nature of time in quantum gravity that could be used to describe dynamics just as effectively as conventional time.”  

The study also demonstrates that a version of the main equation in quantum mechanics (Schrödinger) can still be written using entropic time – enabling predictions of how the ‘probability cloud’ of a quantum system will change over time.  

The experiment addresses a long-standing question in physics - in some theories of the universe, there is no built‑in clock so how do you tell what comes ‘before’ and ‘after’ without external time?  

Professor Barontini showed that the system follows the standard equations of quantum physics and demonstrates that deep questions about the nature of time - usually discussed only in theories about the universe as a whole - can be tested in controlled laboratory experiments.  

The experiment provides a powerful testbed for ideas in quantum cosmology and gravity, meaning that ideas relating to the early universe can now be tested experimentally in the lab.  

The approach could be extended to more complex systems, potentially allowing researchers to probe the physics of the Big Bang and the ‘Big Crunch’. It could also be used to simulate black holes in the lab or test competing theories about how time emerges in the universe. 

ENDS 

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Giovanni Barontini, Professor of Physics, at the University of Birmingham, using the apparatus to trap and cool rubidium atoms. 

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Giovanni Barontini, Professor of Physics, at the University of Birmingham, using the apparatus to trap and cool rubidium atoms. 

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Optics to deliver the lasers on the atoms.   

Credit

University of Birmingham

Antibiotic residues may pose a hidden risk to male fertility





Science China Press

Antibiotic residues may pose a hidden risk to male fertility 

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DHA alleviates Ornidazole toxicity related to spermatogenic dysfunction by modulating PPARγ-dependent ER-mitochondrial uncoupling

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Credit: ©Science China Press





Male infertility is a growing reproductive health concern worldwide. While genetic, hormonal, and reproductive tract disorders are well-recognized causes, environmental exposure and lifestyle-related factors are attracting increasing attention. Some pharmaceutical residues and environmental pollutants may enter the human body through water, soil, or the food chain, but their potential effects on male reproductive health remain incompletely understood.

A new study published in Science China Life Sciences investigated how ornidazole, an antimicrobial drug used in humans, livestock, and aquaculture, may affect male fertility.

The researchers first analyzed serum samples and found that serum ornidazole levels were higher in patients with oligozoospermia than in healthy controls. Higher serum ornidazole levels were also negatively associated with sperm concentration and total normal-progressively motile sperm count, suggesting a possible link between ornidazole-related exposure and reduced sperm quality.

To further explore this association, the team used mouse and cell models and found that ornidazole exposure reduced sperm count and motility, disrupted seminiferous tubule structure, and interfered with meiotic progression. Mechanistically, ornidazole increased the expression of voltage-dependent anion channel 1 (VDAC1), a key protein located at mitochondria-associated endoplasmic reticulum membranes (MAMs). This disrupted MAM balance, promoted mitochondrial calcium overload, impaired mitochondrial function, and triggered oxidative stress.

The researchers also investigated the potential protective effect of DHA, an omega-3 fatty acid found in dietary sources such as fish oil and algal oil. In the mouse model, DHA supplementation significantly improved ornidazole-induced spermatogenic defects. Notably, DHA is readily available to the general public and has a favorable biosafety profile. These features make it a promising therapeutic metabolite for oligoasthenozoospermia induced by environmental pollution.

 

Bing Yao, Jun Jing, and Xie Ge from the Department of Reproductive Medicine, Jinling Hospital Affiliated to Nanjing University, and Yong Wang from Medical School of Nanjing University are the co-corresponding authors. Chuwei Li, Shanmeizi Zhao, Chongli Shi, and Shanshan Sun contributed equally as co-first authors.

Journal

DOI

Plants reveal hidden PFAS pollution that soils can miss, study finds



The Hebrew University of Jerusalem
Potatoes 

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Potatoes

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Credit: Igor Farberov





A new study found that plants may reveal recent PFAS contamination linked to airborne deposition that can go undetected in soil analyses. Conducted in agricultural fields near the conflict zone in southern Israel, the research showed that potato leaves contained substantially higher concentrations of certain PFAS than the surrounding soils, suggesting direct exposure from the atmosphere rather than uptake through roots alone. While the study did not identify specific sources and found no clear relationship between soil PFAS concentrations and distance from the conflict zone, the findings raise the possibility that military-related activities, including the use of aqueous film-forming foams (AFFF) and potentially explosives-related sources, may contribute to atmospheric PFAS deposition. The results suggest that vegetation can serve as a sensitive indicator of recent airborne contamination and complement traditional soil-based environmental monitoring.

 

A new study led by Nitzan Shy, Dr. Shira Rosencwaig, Dr. Tali Ilani, Dr. Evyatar Ben Mordechay, and Prof. Benny Chefetz from the Hebrew University of Jerusalem, the Agricultural Research Organization (ARO) – Volcani Institute, Israel's National Public Health Laboratory (Ministry of Health), and the Southern R&D Center (MOP Darom), has found that vegetation can capture recent airborne contamination from per- and polyfluoroalkyl substances (PFAS), commonly known as "forever chemicals," even when surrounding soils show little evidence of recent pollution.

Published in the Journal of Hazardous Materials, the research suggests that plants may serve as sensitive environmental sentinels, revealing contamination pathways that conventional soil monitoring can overlook and offering a valuable new tool for tracking emerging environmental contaminants.

PFAS are widely used in numerous consumer and industrial products, including water-repellent coatings, non-stick cookware, food packaging materials, firefighting foams, textiles, and many other applications. Due to their exceptional persistence, PFAS can remain in the environment for decades to centuries, with some compounds exhibiting extremely slow degradation rates. As a result, PFAS contamination is now widespread across diverse environmental compartments, including the air we breathe, the food we eat, the water we drink, and the soils on which we grow our crops.

Today, the question is no longer whether people are exposed to PFAS, but rather to what extent. PFAS have been detected in the blood of the vast majority of people worldwide, raising growing concerns about their long-term effects on human health and the environment.

To better understand how PFAS move through agricultural systems, the researchers analyzed soils, potato leaves, and potato tubers collected from agricultural fields in southern Israel. The region provided a unique opportunity to investigate how airborne contaminants move through the environment under complex real-world conditions.

The researchers detected PFAS in soils, leaves, and tubers, but the distribution patterns differed substantially among these environmental compartments. Agricultural soils were dominated by PFAS associated with long-term inputs such as treated wastewater irrigation and biosolid applications. In contrast, potato leaves contained elevated concentrations of short-chain PFAS compounds known to travel efficiently through the atmosphere. In some cases, concentrations in leaves were hundreds of times higher than those measured in the surrounding soil, suggesting that these compounds may have reached plants through direct atmospheric deposition rather than exclusively through root uptake.

While no direct relationship was observed between PFAS concentrations in either cultivated or uncultivated soils and distance from nearby conflict-affected areas, the substantially higher concentrations measured in leaves compared with soils point to the possibility of airborne inputs. The researchers note that PFAS associated with military activities—including compounds originating from aqueous film-forming foams (AFFF) and potentially from explosives-related sources—could represent one possible contributor to such atmospheric deposition. However, the study did not directly identify specific emission sources.

The findings indicate that vegetation may capture a more immediate snapshot of environmental exposure, while soils primarily reflect years or decades of accumulated contamination. In other words, plants can reveal recent contamination events that may become masked within the longer-term environmental record preserved in soils.

Importantly, PFAS concentrations in the edible potato tubers were substantially lower than those measured in the leaves. Although this pattern has been reported previously, the findings further support evidence that leaves and roots are typically the dominant accumulation compartments for PFAS, while transfer to edible fruits and storage organs remains relatively limited.

The study also places the measured concentrations into a broader international context. The number of PFAS compounds detected and their concentrations in soils, leaves, and potato tubers were generally comparable to, or lower than, levels reported in agricultural systems in Europe, Asia, and the United States.

The research highlights a broader challenge for environmental monitoring. In landscapes already affected by historical contamination, emerging pollution sources can be difficult to detect through soil testing alone. Plants, by contrast, may reveal recent atmospheric inputs that remain hidden in soil records.

"Our findings suggest that vegetation can provide unique information about ongoing environmental processes and may serve as an effective indicator of recent airborne contamination," the researchers said. "Understanding these pathways is essential for improving how we monitor and manage environmental pollutants in agricultural landscapes."

The findings also suggest that military activities may represent an additional environmental source of PFAS and potentially other contaminants associated with explosives and combustion processes, warranting consideration in future monitoring efforts. The researchers propose that environmental surveillance programs could benefit from incorporating vegetation and air sampling alongside traditional soil analyses, as these matrices may provide early indications of airborne contaminant deposition that are not readily captured through soil monitoring alone.

D.E.I. IS NOT DEAD

Keck Medicine of USC earns LGBTQ+ Healthcare Equality Leader 2026 designation



Keck Medicine of USC hospitals and USC Student Health earn top score in the Human Rights Campaign Foundation’s 2026 Healthcare Equality Index



University of Southern California - Health Sciences

Keck Medicine of USC hospitals and USC Student Health earn top score in the Human Rights Campaign Foundation’s 2026 Healthcare Equality Index 

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Keck Medicine of USC raised the Pride Flag on June 1, 2026, to kick off National LGBTQ+ Pride Month.

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Credit: Ricardo Carrasco III






LOS ANGELES — Keck Medicine of USC hospitals and USC Student Health, part of Keck Medicine, received the LGBTQ+ Healthcare Equality Leader designation in the Human Rights Campaign Foundation’s 2026 Healthcare Equality Index (HEI).  

HEI is the industry standard benchmarking tool for LGBTQ+ inclusion and equity practices in the healthcare field, judging hospitals on five criteria: 

  • Non-Discrimination and Staff Training 

  • Patient Services and Support 

  • Employee Benefits and Policies 

  • Patient and Community Engagement 

  • Responsible Citizenship  

To receive LGBTQ+ Healthcare Equality Leader designation, healthcare facilities must receive the maximum score in each criteria and earn an overall score of 100.  

“Every patient deserves safe and respectful care, and Keck Medicine is proud to serve the diverse needs of the LGBTQ+ community,” said Rod Hanners, CEO of Keck Medicine. “This recognition reflects our commitment to delivering personalized, compassionate medicine and fostering a welcoming, inclusive environment for all.”  

Keck Medicine hospitals include Keck Hospital of USC, USC Norris Cancer Hospital,USC Verdugo Hills Hospital (USC-VHH) and USC Arcadia Hospital (USC-AH). This marks the eighth time that Keck Hospital, USC Norris and USC-VHH have received the LGBTQ+ Healthcare Equality Leader distinction, and the second time that USC-AH has received the designation since joining Keck Medicine in 2022.  

USC Student Health, which provides comprehensive healthcare to USC students, participated in the survey for the third time and joins a select group of college healthcare providers in receiving the leader designation.  

Commitment to Inclusivity and Equity 

Keck Medicine leads multiple initiatives and programs in support of the LGBTQ+ community, demonstrating a commitment to inclusivity and equity.  

  • The USC Gender Affirming Care Program offers evidence-based comprehensive healthcare tailored to transgender, non-binary and gender-diverse patients. The program’s dedicated patient navigator assists patients with their personalized needs throughout their healthcare journey.  

  • The health system is a sponsor of the Latino Equality Alliance LGBTQ+ Youth College Scholarship Program, which includes a Keck Medicine scholarship to support LGBTQ+ students pursuing healthcare careers. 

  • The health system collaborates with several local LGBTQ+ nonprofit organizations, including The TransLatin@ Coalition, a trans-led nonprofit organization that advocates for the needs of transgender, gender non-conforming and intersex immigrants; and Bienestar, a community-based social services organization addressing emerging health issues faced by Latinx and LGBTQ+ populations.   

  • Since 2015, the Keck Pride employee resource group, has been a pillar in creating a welcoming environment for LGBTQ+ patients, families and staff, and is a driving force in many of the health system’s initiatives.  

The Human Rights Campaign Foundation is the educational arm of the Human Rights Campaign, a civil rights organization working to achieve equity for LGBTQ+ people.  

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For more information about Keck Medicine of USC, please visit news.KeckMedicine.org