Monday, March 02, 2026

 

Women more likely to choose wine from female winemakers





Washington State University





PULLMAN, Wash. — Promoting women’s ownership in wineries can boost sales among the largest group of U.S. wine consumers, who happen to be women.

Messages like “proudly made by a woman winemaker” increased women’s intentions of purchasing wines, particularly when the label’s artwork reinforced the point with feminine gender cues such as flowers. Women were also willing to pay higher prices for those wines, according to the research from Washington State University and Auburn University.

The findings are noteworthy because 59% of all wine purchases in the United States are made by women, said Christina Chi, coauthor of the research and professor of hospitality business management at WSU’s Carson College of Business.

Wine is often considered a cultural product, where the winemaker’s identity plays a role in shaping the brand’s image, she said.

Women winemakers, however, are less likely than their male counterparts to include their names on bottle labels or draw attention to their gender. Their reluctance may stem from concerns about prejudice toward their products in the male-dominated wine industry, Chi said.

“Our findings suggest that women winemakers and winery owners can benefit by being more visible,” she said. “The research shows that they can disclose their ownership with confidence and leverage it as a marketing strategy.”

The possibilities include putting “women-made wine” statements on labels or packaging, and retail store displays featuring women-made wines.

Demi Deng, an assistant professor at Auburn who earned her doctorate at WSU, is the first author on the research published in International Journal of Hospitality Management. Ruiying Cai, an assistant professor of hospitality business management at WSU, also contributed.

The new findings build on earlier studies showing that women are more inclined to buy wine with feminine gender cues on the labels. The 2024 research – by Cai, Chi, Deng, and WSU Emeritus Professor Robert Harrington – received widespread publicity. Beverage trade journals carried the story, and women winemakers were enthusiastic about the findings.

“As researchers, we want our work not only to have societal impact, but to have practical significance for the wine industry,” Chi said. “From the response, we saw that women winemakers were following our research and were eager for additional studies about women wine consumers.”

More than 1,000 U.S. women participated in the most recent research, which involved a three-part study.

First, the researchers replicated the 2024 findings about feminine cues on wine labels. Using a fictitious Columbia Valley red table wine, the women surveyed expressed higher intentions of purchasing the wine when the label’s artwork featured a bouquet of flowers versus a masculine portrait. They were also willing to pay $3.50 more per bottle – about $17.75 for wines with feminine labels compared to $14.25 for wines with masculine cues.

In the second phase of the study, a “woman-made wine” statement was added to marketing materials. Women consumers had even stronger purchase intentions for wines with both the statement and feminine artwork on labels, the research found.

In the final phase, photos of women winemakers were further added to the marketing materials. But women were less likely to buy feminine-label wines when the female winemakers were pictured. Rather than focusing on the “woman-made” messaging, consumers’ decisions may have been swayed by whether they related to the individual women portrayed in the photographs, researchers said.

The studies also tested the marketing strategies on wines with masculine labels. Adding a “woman-made” statement significantly increased their appeal to women consumers. And when female winemakers were pictured in the marketing materials, women were willing to pay $3 more per bottle for wines with masculine labels.  

Besides helping women winemakers market their products, Deng said she hopes the research will draw attention to women’s contributions to the industry. In the United States, about 18% of winemakers are women.  

Deng worked as a sommelier in New Zealand before she earned her doctorate. “I actually encountered a lot of women winemakers, but their names aren’t visible in the wine market,” she said.

 

All-fluorinated electrolyte unlocks the potential of high-voltage lithium metal batteries




Tsinghua University Press
High-Voltage Stability LNMO Batteries Enabled by All-Fluorinated Electrolyte 

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The cycle performance of Li//LNMO cells at 1 C rate. The red line represents the new All-Fluorinated Electrolyte (AFE), which maintains significantly higher capacity and stability over 250 cycles compared to the standard carbonate electrolyte (blue line), enabling long-lasting high-voltage operation.

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Credit: Energy Materials and Devices, Tsinghua University Press






As the global demand for electric vehicles (EVs) accelerates, the race is on to develop batteries that offer higher energy density, lower costs and reduced reliance on scarce resources like cobalt. Spinel LiNi0.5Mn1.5O4 (LNMO) has emerged as a top contender for next-generation cathodes due to its high operating voltage (4.7 V vs. Li+/Li) and cobalt-free composition. However, its commercial adoption has been stalled by a critical flaw: electrochemical instability. Standard carbonate-based electrolytes break down under the high-voltage conditions required by LNMO, leading to rapid performance fading.

 

Now, a team of researchers led by Huolin Xin from University of California, Irvine has developed a solution: an all-fluorinated electrolyte (AFE) that acts as a stabilizer for these high-voltage systems. Their findings were published in the journal Energy Materials and Devices on December 1, 2025.

 

"To boost the energy density of batteries, we need to push the voltage limits. But conventional electrolytes are like using an oil that burns off when the engine gets too hot—they simply oxidize and decompose at voltages above 4.2 V," said Peichao Zoua former postdoctoral researcher in the research group. "Our goal was to design an electrolyte that could withstand the aggressive 4.7 V environment of LNMO cathodes."

 

The team’s solution involves replacing traditional solvents with fluorinated counterparts combined with a boron-containing additive (TMSB). Fluorinated solvents have special chemical properties that make them resistant to oxidation. In testing, the new AFE demonstrated an impressive stability window, enduring voltages up to 6.5 V without decomposing.

 

The secret to this enhanced performance lies in the interface. The study reveals that the AFE promotes the formation of a robust Cathode-Electrolyte Interphase (CEI) layer rich in fluorine and boron.

 

"Think of the CEI layer as a protective skin that forms on the cathode," explained Peichao Zou. "With standard electrolytes, this skin is weak and keeps breaking, consuming the battery's fluid. Our fluorinated electrolyte builds a tough, stable armor that stops side reactions and prevents the metal structure of the cathode from dissolving."

 

The results are significant for the future of battery longevity. In comparative tests, Li//LNMO cells using the new AFE retained 84.1% of their capacity after 250 cycles at a high cut-off voltage of 4.9 V, significantly outperforming cells with standard electrolytes. Furthermore, the battery showed remarkable resilience at elevated temperatures (50°C), a common condition in real-world EV usage, where standard batteries typically degrade fastest.

 

While the study marks a major step forward, the team acknowledges that challenges remain, particularly regarding operation in freezing conditions. The fluorinated electrolyte currently exhibits higher viscosity, which can slow down ion movement at temperatures like -10°C.

"This study presents a facile and effective approach to promoting the commercialization of high-voltage LNMO cathodes," said Lulu Ren, a former postdoctoral researcher in the research group. "Our next steps involve optimizing the formula to improve low-temperature conductivity and fast-charging capabilities, ensuring these batteries are ready for all-climate applications."

As health care goes digital, patients are being left behind




University of California - San Francisco





Patients are now expected to navigate much of their care online — from seeing their doctor on a screen to booking appointments, refilling prescriptions, and checking test results through health care portals.  

Yet, according to a new study by UC San Francisco, most health systems are skipping a crucial step: asking whether their patients have the access and skills to use these digital tools.  

The researchers surveyed nearly 150 clinicians and informatics leaders from health care systems across the country during the first half of 2024. Just 44% said they asked their patients if they could use digital devices. Among the institutions that serve uninsured patients, just one-third asked.  

“Not everyone can access all these new digital health tools we’re rolling out, and the people who are excluded are often those who experience worse health outcomes and limited access to care,” said Elaine C. Khoong, MD, associate professor of medicine at UCSF and a faculty member with the UCSF Action Research Center for Health.  

Khoong is the senior author of the paper, which appeared Feb. 25 in the journal JMIR Formative Research. The research was funded by the National Institutes of Health (NIH).  

As a general internist and clinical informaticist, Khoong has seen patients miss critical messages sent through the hospital’s online app because they didn’t know they had an account. Others were sent text or email links but didn’t understand how to open them.  

She and her co-authors say health care organizations should train their health workers to screen for digital readiness using standardized tools, and policy makers should create stronger incentives for health systems to do this type of assessment. They recommended that it should be incorporated into other routine screenings for things like housing instability, food insecurity, and domestic abuse.  

Those who responded to the survey said the lack of time and resources were their biggest barriers to screening. And among those who did screen, nearly half said they did not have the resources to help their patients access or learn to use the organization’s online tools.  

Since the survey, Congress made cuts to federal digital access programs. In June of 2024, the Affordable Connectivity Program, which is the nation’s largest internet subsidy for low-income households, shut down after Congress failed to renew its funding. 

Authors: Jonathan J. Shih and Andersen Yang, MPH, of UCSF, are co-first authors of the study. Other UCSF co-authors include Vivian E. Kwok, MPH, Emilia H. De Marchis, MD, Marika Dy, MPH, Carmen Ma, Nilpa D. Shah, MPH, Kelsey H. Natsuhara, MD, Urmimala Sarkar, MD, MPH, and Anjana E. Sharma, MD. For all authors, see the paper.  

Funding:  This study was supported by the NIH’s National Center for Advancing Translational Sciences (UCSF-CTSI UL1 TR001872), National Institute on Aging (P30AG015272), National Heart Lung and Blood Institute (K23HL1577500), and National Institute of Minority Health and Health Disparities (K23MD016439). Additional funders include the UCSF Population Health and Health Equity Funding and the California Health Care Foundation.  

Conflicts: None declared.  

About UCSF: The University of California, San Francisco (UCSF) is exclusively focused on the health sciences and is dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. UCSF Health, which serves as UCSF’s primary academic medical center, includes among the nation's top specialty hospitals and other clinical programs, and has affiliations throughout the Bay Area. UCSF School of Medicine also has a regional campus in Fresno. Learn more at ucsf.edu or see our Fact Sheet.

 

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Worming out molecular secrets behind collective behavior



Indian Institute of Science (IISc)
Swarm formation in C. elegans 

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Swarm formation in casy-1 mutant worms, demonstrating aggregate feeding and coordinated movement across the food lawn boundary

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Credit: Navneet Shahi




Studying social behaviour is crucial for understanding how certain neuromodulatory pathways – like the serotonin pathway, which influences mood and social interactions – are regulated. 

Kavita Babu, Professor at the Centre for Neuroscience (CNS), Indian Institute of Science (IISc), and her lab have been investigating these signalling mechanisms using the worm Caenorhabditis elegans. In a new study published in the Proceedings of the National Academy of Sciences, they report that the disruption of a single conserved synaptic gene alters the signalling of a specific neuropeptide, resulting in the worms showing an unusual type of swarming behaviour. This swarming resembles serotonin-driven swarming described in other species, such as desert locusts, suggesting that neuromodulatory control of social behaviour might be evolutionarily conserved. 

Navneet Shahi, PhD student at CNS and first author, was initially working on mutant worms for a different project when she noticed something unexpected. Instead of dispersing towards food that was nearby, like wild type worms, these mutants preferred to swarm collectively instead, even if it resulted in starvation. This behaviour appeared repeatedly and reproducibly over multiple experiments.

In order to delve deeper into this phenomenon, the IISc researchers reached out to physicists at Koç University, Turkey, who modelled the movement of the worms. Together, the team found that this behaviour was “self-emergent” and that even a single worm could give rise to group-level swarming over multiple generations – a novel finding. 

Using genetic manipulation techniques like CRISPR, the team then generated mutants lacking a specific gene coding for a protein called CASY-1. CASY-1 is a distant relative of the conserved calsyntenin protein found in higher organisms including humans. The mutation in CASY-1 was found to disrupt signalling by a neuropeptide called pigment dispersing factor (PDF). This essentially unlocked serotonin signalling pathways that are usually kept in check, driving the worms into their crowded, swarming state. Studying these targeted genetic mutants led the researchers to ask the broader question of whether the roots of social behaviour might be genetically encoded. 

The researchers also wanted to see if they could control this behaviour in real time via optogenetics – using light pulses to instantly activate or silence specific neurons and watching whether the worms huddled or dispersed. Capturing this behaviour in a time-lapse video was “intriguing,” says Babu.  

“Initially, we suspected the role of pheromones or external environmental factors in this aggregative behaviour. However, we soon realised that was not the case,” adds Shahi. They found that serotonergic signalling was the master regulator, essentially “tuning” how these worms interact as a group.

While social feeding behaviours have been studied by researchers in the past, such collective movement is relatively less explored. This piqued Shahi’s interest in investigating the molecular pathways involved. C. elegans also makes for a great model system mainly due to its well-characterised nervous system and the ease of studying population-level behaviours within a short period of time, especially those arising repeatedly and reproducibly. 

In future studies, the team plans to investigate how specific genetic perturbations produce different outcomes under varying environmental conditions, in order to understand fundamental rules governing collective behaviour across species. 


Network-like aggregation patterns formed by casy-1 mutants under starvation conditions 

Network-like aggregation patterns formed by casy-1 mutants under starvation conditions

Credit

Navneet Shahi

Time-lapse video of swarm formation in casy-1 mutant worms, demonstrating aggregate feeding and coordinated movement across the food lawn boundary [VIDEO]