Monday, November 17, 2025

 

Wearable lets users control machines and robots while on the move




University of California - San Diego
motion wearable 1 

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Wearable technology uses everyday gestures to reliably control robotic devices even under excessive motion noise, such as when the user is running, riding in a vehicle or in environments with turbulence. 

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Credit: David Baillot/UC San Diego Jacobs School of Engineering






Engineers at the University of California San Diego have developed a next-generation wearable system that enables people to control machines using everyday gestures — even while running, riding in a car or floating on turbulent ocean waves.

The system, published on Nov. 17 in Nature Sensors, combines stretchable electronics with artificial intelligence to overcome a long-standing challenge in wearable technology: reliable recognition of gesture signals in real-world environments.

Wearable technologies with gesture sensors work fine when a user is sitting still, but the signals start to fall apart under excessive motion noise, explained study co-first author Xiangjun Chen, a postdoctoral researcher in the Aiiso Yufeng Li Family Department of Chemical and Nano Engineering at the UC San Diego Jacobs School of Engineering. This limits their practicality in daily life. “Our system overcomes this limitation,” Chen said. “By integrating AI to clean noisy sensor data in real time, the technology enables everyday gestures to reliably control machines even in highly dynamic environments.”

The technology could enable patients in rehabilitation or individuals with limited mobility, for example, to use natural gestures to control robotic aids without relying on fine motor skills. Industrial workers and first responders could potentially use the technology for hands-free control of tools and robots in high-motion or hazardous environments. It could even enable divers and remote operators to command underwater robots despite turbulent conditions. In consumer devices, the system could make gesture-based controls more reliable in everyday settings.

The work was a collaboration between the labs of Sheng Xu and Joseph Wang, both professors in the Aiiso Yufeng Li Family Department of Chemical and Nano Engineering at the UC San Diego Jacobs School of Engineering.

To the researchers’ knowledge, this is the first wearable human-machine interface that works reliably across a wide range of motion disturbances. As a result, it can work with the way people actually move.

The device is a soft electronic patch that is glued onto a cloth armband. It integrates motion and muscle sensors, a Bluetooth microcontroller and a stretchable battery into a compact, multilayered system. The system was trained from a composite dataset of real gestures and conditions, from running and shaking to the movement of ocean waves. Signals from the arm are captured and processed by a customized deep-learning framework that strips away interference, interprets the gesture, and transmits a command to control a machine — such as a robotic arm — in real time.

“This advancement brings us closer to intuitive and robust human-machine interfaces that can be deployed in daily life,” Chen said.

The system was tested in multiple dynamic conditions. Subjects used the device to control a robotic arm while running, exposed to high-frequency vibrations, and under a combination of disturbances. The device was also validated under simulated ocean conditions using the Scripps Ocean-Atmosphere Research Simulator at UC San Diego’s Scripps Institution of Oceanography, which recreated both lab-generated and real sea motion. In all cases, the system delivered accurate, low-latency performance.

Originally, this project was inspired by the idea of helping military divers control underwater robots. But the team soon realized that interference from motion wasn’t just a problem unique to underwater environments. It is a common challenge across the field of wearable technology, one that has long limited the performance of such systems in everyday life.

“This work establishes a new method for noise tolerance in wearable sensors,” Chen said. “It paves the way for next-generation wearable systems that are not only stretchable and wireless, but also capable of learning from complex environments and individual users.”

Full study: “A noise-tolerant human-machine interface based on deep learning-enhanced wearable sensors.” Co-first authors on the study are UC San Diego researchers Xiangjun Chen, Zhiyuan Lou, Xiaoxiang Gao and Lu Yin.

This work was supported by the Defense Advanced Research Projects Agency (DARPA, contract number HR001120C0093).

The wearable system glued onto a cloth armband.

Credit

David Baillot/UC San Diego Jacobs School of Engineering

Using robotic testing to spot overlooked sensory deficits in stroke survivors



University of Delaware study could pave the way for more precise rehabilitation



University of Delaware

Detecting hidden sensory loss 

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Joanna Hoh, a biomechanics and movement science (BIOMS) doctoral student at the University of Delaware, tests Don Lewis’ sensory loss in his arm post-stroke using a KINARM robotic exoskeleton.

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Credit: Ashley Barnas Larrimore/ University of Delaware





A decade ago, at age 55, Don Lewis suffered a stroke in his sleep. When he woke up, he couldn’t move his left arm or leg. Lewis’ neighbor realized his truck hadn’t moved in two days and called 911 for a welfare check. When paramedics found him, he was paralyzed on one side.

“At the hospital, they told me an aneurysm caused my stroke,” he said.

He would remain there for two months, and after extensive physical therapy, Lewis regained use of his left leg. His left arm remains paralyzed.

“I feel pain when I hit it or scrape it walking through a doorway, but I can’t control the motion.”

Since then, the cancer survivor has had two more strokes. 

Now, Lewis is helping University of Delaware researchers understand one of the most overlooked challenges in stroke recovery – proprioception, the body’s ability to sense movement and position.

“To simplify the concept, in class, I tell my undergraduates to close their eyes and touch their nose; if people can’t do that, it means they likely have impaired proprioception,” said Jennifer Semrau, associate professor of kinesiology and applied physiology, in the College of Health Sciences.

In findings recently published in Neurorehabilitation and Neural Repair, Semrau and doctoral candidate Joanna Hoh suggest it’s possible to identify hidden sensory losses after stroke without requiring patients to move their affected arm. This advance could make assessments more accessible in clinical settings.

Assessing movement

Inside the lab, Lewis is placed in a KINARM robotic exoskeleton that tracks upper limb movement, allowing Semrau to better understand the neural and behavioral mechanisms that contribute to his recovery of sensory and motor function. 

Semrau’s lab used several tests, including a new one – the single-arm measurement- to gauge perception-based movement. The test moves Lewis’ stroke-affected arm robotically while he responds with his non-affected arm if he can feel the movement of his stroke-affected arm.

“We’re trying to determine the lowest level someone can detect their arm moving,” Semrau said.

The average person, who hasn’t had a stroke, can feel as little movement as a half centimeter. For people post-stroke, it varies. 

“Some can’t tell their arm was moved 10 centimeters, and that could be the difference between touching a hot stove or a knife in the kitchen,” Semrau said.

The communication from the brain to the receptors in the muscles, which are responsible for detecting movement, is disrupted after a stroke.

“When you move, the receptors lengthen or shorten, and if the information isn’t getting from the brain to those muscle receptors, you can’t properly coordinate movement,” Semrau said. 

However, someone with a proprioceptive deficit could still feel pain and may not have a touch impairment.

“Pain is part of the somatosensory system and is relayed on a different set of nerves. After a stroke, some may have increased or decreased sensitivity to pain, and it’s the same with touch,” Semrau said. “Every person is a fingerprint--impairments each person has after a stroke are unique and require individualized treatment." 

The difficulty Semrau faces: it’s challenging to tease apart sensory deficits from motor deficits because they’re deeply intertwined. 

“It’s hard to determine whether the issue is the person’s ability to feel the arm or their ability to move,” she said. “The tasks we’re studying in our lab get to the heart of the matter.”

From clinic to the classroom

Hoh, an occupational therapist, became interested in upper-limb stroke research after working with patients in rehabilitation. 

“We often think about movement through motor function,” said Hoh. “I had a blind spot to the sensory system in terms of stroke recovery and realized this is an avenue we don’t consider enough as clinicians.”

That inspired her to pursue her doctorate in biomechanics and movement science at UD. Her dissertation focuses on individuals with sensory issues following a stroke and how these issues affect their daily activity levels.

Semrau hopes their ongoing research will raise awareness of the problem and encourage more clinicians to integrate this kind of precision testing. 

“In one of our studies, we found that just 1% of clinicians assess proprioception in people with stroke,” Semrau said. “It’s a newer area, but research also shows that without sensory recovery, a person will not gain full recovery of function after a stroke.” 

To develop a personalized medicine approach to treatment, both Semrau and Hoh emphasized the need for a better understanding of post-stroke impairments.

“The onus is on clinicians and researchers to ensure they’re testing for sensory deficits. Just because someone is impaired motorically, it doesn’t mean they will or won’t be impaired sensory-wise,” Hoh said. 

Semrau added, “Understanding the connection between motor and sensory impairments that affect function is key to better targeting therapies and tailoring recovery for each individual.” 

 

ACP encourages all adults to receive the 2025-2026 influenza vaccine




American College of Physicians





Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent.    
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1. ACP encourages all adults to receive the 2025-2026 influenza vaccine 

Abstract: https://www.acpjournals.org/doi/10.7326/ANNALS-25-04056  

URL goes live when the embargo lifts               

The American College of Physicians (ACP) issued new influenza vaccine practice points that say everyone ages 18 to 64 years who are not pregnant or immunocompromised should receive either a standard-dose trivalent or a standard-dose quadrivalent (cell-based, egg-based, MF59-adjuvanted, or recombinant) influenza vaccine for the 2025-2026 influenza season. Those aged 65 years or older who are not immunocompromised should receive either a high-dose trivalent or a high-dose quadrivalent egg-based influenza vaccine. ACP did not examine evidence or make recommendations for pregnant women or immunocompromised adults. The practice points are published in Annals of Internal Medicine. 

 

Influenza A and B drive seasonal epidemics because they are highly infectious, rapidly mutate, and cause a respiratory infection known as the flu. Incidence and severity of influenza vary by year and season but is greatest in the fall and winter. Adults aged ≥ 65 years and adults with comorbidities, such as diabetes, asthma, or chronic obstructive pulmonary disease (COPD), are at greater risk for morbidity and mortality.   

 

To develop its practice points, ACP explored new evidence and analyzed the comparative effectiveness and harms of influenza vaccines in adults aged ≥ 18 years who are not pregnant or immunocompromised. Influenza vaccines help prevent morbidity and mortality. 

 

ACP’s Practice Points are based on a rapid review of the best available evidence of the benefits and harms of trivalent (three different influenza viruses or viral proteins) and quadrivalent (four different influenza viruses or viral proteins) influenza vaccines in nonpregnant and nonimmunocompromised adults aged ≥ 18 years. The ACP Center for Evidence Reviews (ACP CER) team evaluated 42 studies, which had two comparators. The most common comparator was the standard dose trivalent or quadrivalent egg-based influenza vaccine. The other comparator was the high-dose trivalent or quadrivalent egg-based influenza vaccine. The ACP considered evidence on benefits (influenza-associated pneumonia/lower respiratory tract disease, influenza-related mortality influenza-related hospitalization, and laboratory-confirmed influenza) and harms (fever, idiopathic thrombocytopenic purpura, and serious adverse events) of the influenza vaccines to develop the Practice Points. 

 

Media contacts: For an embargoed PDF or to speak with someone at ACP, please contact Angela Collom at acollom@acponline.org.  

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2. 1 in 10 physicians receive mental health and substance abuse care  

Abstract: https://www.acpjournals.org/doi/10.7326/ANNALS-24-01069  

URL goes live when the embargo lifts               

A brief research report examined temporal patterns in mental health and substance use (MHSU)-related health care visits among physicians in Ontario, CA over a 19-year period. The findings revealed 1 in 10 physicians received mental health care over the study period, with substantial increases seen during the first two years of the COVID-19 pandemic. The findings highlight a longstanding pattern of physician mental health that was exacerbated by the pandemic. The report is published in Annals of Internal Medicine.   

  

Researchers from North York General Hospital and colleagues studied health administrative data from 29,662 of early (first five years of independent practice) and mid-career (sixth through 15th year of independent practice) physicians who registered with the College of Physicians and Surgeons of Ontario between 1990 and 2018. The researchers examined MHSU visits overall, by visit type (anxiety, mood, and substance use disorders; attention deficit–hyperactivity disorder; adjustment reactions; and other), and by specialty (family medicine, psychiatry, and all other specialties). In a cohort of physician spanning all specialties they found that 11.0% of physicians had one or more outpatient MHSU visits during the study period. During the prepandemic period (2003-2019), the proportion of physicians with MHSU visits per year was stable at around 12%. This proportion increased during the COVID-19 pandemic, going from 14.6% in 2020–2021 to 15.2% in 2021–2022. This increase could reflect the reduced barriers to and stigma around mental health care seen during the pandemic, but it also might reflect greater mental distress in physicians because of the pandemic. MHSU visits by physicians for anxiety disorders and adjustment reactions saw the greatest increases. The authors suggest that system-level changes and target interventions for higher-risk physician groups are needed.   

  

Media contacts: For an embargoed PDF, please contact Angela Collom at acollom@acponline.org. To contact corresponding author Daniel T. Myran, MD, MPH please email Misty Pratt at misty.pratt@ices.on.ca.  

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3. Mindfulness interventions and professional coaching are effective strategies for managing health care professional burnout 

Abstract: https://www.acpjournals.org/doi/10.7326/ANNALS-25-00469  

Editorial: https://www.acpjournals.org/doi/10.7326/ANNALS-25-04277  

URL goes live when the embargo lifts               

A systematic review and meta-analysis evaluated the effectiveness of all interventions to mitigate burnout among health care professionals (HCPs). The review found that mindfulness-based interventions may reduce burnout in nurses, midwives, and a mixture of HCPs. However, professional coaching likely reduces burnout among doctors, especially when sustained for more than 4 weeks. The findings are published in Annals of Internal Medicine.    

  

Researchers from Queen Mary University of London and Barts Healthcare NHS Trust and colleagues analyzed findings from 93 randomized controlled trials (RCTs) and 6 cluster RCTs evaluating interventions to mitigate burnout compared with no active intervention among HCPs. Included studies had to have been conducted for HCPs directly involved in patient care, evaluate modifiable intervention strategies against no active intervention, and include a continuous outcome related to burnout measured with a validated assessment tool. Components of burnout evaluated were emotional exhaustion (EE), depersonalization, and personal accomplishment (PA). Interventions examined in the studies included mindfulness-based interventions, resilience or stress-management training, skills training for specific job functions, Baliant group sessions, and professional coaching. The analysis found that different interventions were effective for different HCP roles. There was evidence, albeit of low certainty, that mindfulness–meditation-based interventions may result in a significant reduction in EE among nurses and midwives and may result in a moderate reduction in EE among a mixture of various HCP samples, but the same was not observed among medical doctors. For medical doctors, there was evidence of moderate certainty that professional coaching may result in a significant reduction in EE among medical doctors. For depersonalization, mindfulness-based programs may reduce depersonalization among a mixture of various HCP samples, and professional coaching was significantly associated with reduced depersonalization among medical doctors. For PA, there was moderate-certainty evidence that mindfulness–meditation-based interventions improved PA for a mixture of HCPs, but evidence was of very low certainty among nurses and midwives. These results can be used to inform support strategies to mitigate and address burnout for HCPs, especially primary care physicians and nurses.   

  

Media contacts: For an embargoed PDF, please contact Angela Collom at acollom@acponline.org. To contact corresponding author Ajay Gupta, please email Faustine Akwa at f.akwa@qmul.ac.uk.  

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4. Temperature-related deaths disproportionately affect older adults, men, and non-Hispanic Black persons 

Abstract: https://www.acpjournals.org/doi/10.7326/ANNALS-25-01006  

URL goes live when the embargo lifts               

A brief research report analyzed long-term national trends in temperature-related mortality in the United States. The report found that heat- and cold-related deaths accounted for 0.1% of total mortality over the study period, disproportionately affecting older adults, males, and Non-Hispanic Black persons (NHBPs). The findings highlight the need for targeted public health strategies such as improved housing insulation, accessible cooling/heating centers, and robust early warning systems to mitigate temperature-related mortality disparities. The report is published in Annals of Internal Medicine.    

  

Researchers from Massachusetts General Hospital-Harvard Medical School, Harvard T.H. Chan School of Public Health, and Suez Canal University used the Centers for Disease Control and Prevention’s WONDER platform to analyze death certificates of 69,256 deaths between 1999 and 2024 in which temperature was recorded as a contributing or underlying cause. They found that of the 69,256 temperature-related deaths, 35% were heat-related and 65% were cold-related. In demographic-specific analyses, adults 65 years and older and males had higher temperature-related mortality than their respective counterparts. NHBPs had the highest heat-related mortality rates, which were twice that of Non-Hispanic White persons, and the highest cold-related mortality rates, which were close to twice that of Non-Hispanic White persons. There was not a consistent increase in temperature-related mortality throughout the study period, but crude estimates were higher during the latter years.    

  

Media contacts: For an embargoed PDF, please contact Angela Collom at acollom@acponline.org. To contact corresponding author Shady Abohashem, MD, MPH please email SAbohashem@mgh.harvard.edu 

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