Monday, November 17, 2025

 END AUSTERITY INVEST IN PUBLIC SERVICES

Cracking the social care workforce crisis with improved pay and training practices


King's College London




Investing in staff pay and training can address the workforce crisis in adult care and improve care home performance, according to new research published in the latest issue of the journal Human Resources Management.  

The researchers looked at data from 36,460 establishments over a five-year period, during which they employed 1.9 million workers in total. They tracked the care providers’ HR practices and outcomes, including investment in staff training, promotion opportunities, job security, working hours, contractual arrangements, staff turnover and average tenure and studied the impact they had on the care home’s performance, as measured by its success in attracting new residents. 

They found that care homes that increased investment in staff training, experienced a 4% increase in new residents; while care homes in which pay and conditions improved had, on average, a 3.1% increase in new residents. 

Dr. Andreas Georgiadis, Associate Professor in International Business and Economics at Leeds University Business School, said: “Addressing the adult care crisis in England requires the government to support care providers to invest in their staff through offering better pay and working conditions and providing training.” 

Dr. Andreas Kornelakis, Reader in Comparative Management at King’s Business School, King’s College London, said: “These findings show how short-sighted HR strategies based on cutting costs via low-skills investment and low-pay growth, are likely to be counterproductive and undermine the care homes’ longer-term operational success.” 

The researchers also concluded that the effectiveness of improved pay and training practices is expected to reduce after a threshold level of collective staff skills, knowledge and experience is reached.

At this point, to improve performance further, other interventions are needed, for instance, improving operational efficiencies or the adoption of new technologies. 

Investing in nurses reduces physician burnout, international study finds



University of Pennsylvania School of Nursing





PHILADELPHIA (November 17, 2025) – A landmark international study finds that hospitals with better nurse staffing and work environments not only benefits nurses but is significantly associated with less physician burnout and job dissatisfaction. The research, published in JAMA Network Open, provides a clear solution to the global crisis of physician burnout.

A research team, led by Penn Nursing’s Center for Health Outcomes and Policy Research (CHOPR), surveyed more than 6,400 physicians and 15,000 nurses across the United States and six European countries (Belgium, England, Germany, Ireland, Norway, and Sweden). The findings show that hospitals with better nurse staffing, supportive work environments, and effective interdisciplinary teamwork had substantially lower rates of physician burnout, job dissatisfaction, and intent to leave.

“Physician burnout is a global crisis, but few actionable solutions have been identified,” said Linda H. Aiken, PhD, RN, FAAN, FRCN, Professor of Nursing and Sociology and Founding Director, CHOPR. “Our study provides evidence that investing in nurses is a ‘two-for-one’ solution—improving both nurse and physician wellbeing while also strengthening patient care.”

Key findings include:

  • In US hospitals, a modest 10% improvement in the nurse work environment including staffing adequacy was associated with a 22% reduction in physician intent to leave, a 25% reduction in physicians unwilling to recommend their hospital as a place to work, a 19% reduction in physician job dissatisfaction, and a 10% reduction in physicians experiencing high burnout.
  • In European hospitals, a 10% increase in nurse staffing adequacy was linked to 20% lower physician intent to leave, 27% lower odds of not recommending their hospital, 15% lower physician job dissatisfaction, and 12% lower odds of high burnout.
  • Hospitals with stronger physician-nurse teamwork consistently reported better physician outcomes.

The results come at a critical time, as both physicians and nurses face unprecedented levels of stress, burnout, and turnover. According to the study, between 20–44% of physicians surveyed reported intentions to leave their hospital positions due to dissatisfaction, and up to 45% reported high burnout.

“These findings highlight a path forward that hospital leaders can act on immediately,” said Karen B. Lasater, PhD, RN, the Jessie M. Scott Term Chair in Nursing and Health Policy, Associate Professor, and Associate Director, CHOPR. “Improving nurse staffing and creating supportive work environments are organizational reforms that are feasible, evidence-based, and capable of retaining both nurses and physicians.”

The research was conducted by the Magnet4Europe Consortium in collaboration with the U.S. Clinician Well-Being Study Consortium, with support from the National Institute of Nursing Research and the European Union’s Horizon 2020 program. The full study, “Informing Hospital Physician Wellbeing Interventions in Europe and the United States: A Cross-sectional Study,” is available open access in JAMA Network Open.

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About the University of Pennsylvania School of Nursing

The University of Pennsylvania School of Nursing (Penn Nursing) is one of the world’s leading nursing schools. It has been ranked the #1 nursing school in the U.S. by QS University for a decade. Our Bachelor of Science in Nursing (BSN) is among the top-ranked programs in the nation, according to the 2026 U.S. News & World Report’s Best Colleges rankings. Penn Nursing also consistently earns high rankings in U.S. News & World Report’s annual list of best graduate schools and is a top recipient of National Institutes of Health (NIH) funding for nursing research. Penn Nursing prepares nurse scientists and nurse leaders to meet the health needs of a global society through innovation in research, education, and practice. Follow Penn Nursing on: FacebookLinkedInYouTube, & Instagram.

About the Center for Health Outcomes and Policy Research: The Center for Health Outcomes and Policy Research at the University of Pennsylvania School of Nursing is dedicated to building the actionable evidence base needed to advance effective policy, practice, and health system reforms that improve health outcomes, cultivate clinician well-being, and promote health equity across communities.

 

UVA modelers and software designers help build ‘immune systems’ for healthier buildings



UVA team is part of multi-institution, interdisciplinary effort funded by ARPA-H



University of Virginia School of Engineering and Applied Science

Portrait of Madhav Marathe 

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Madhav Marathe is a professor of computer science at the University of Virginia and executive director of the Biocomplexity Institute.

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Credit: UVA Biocomplexity Institute





Computer science professor Madhav Marathe is leading Biocomplexity Institute researchers at the University of Virginia to develop the “brains” behind a next-generation system designed to make buildings smarter, safer and healthier for their occupants. 

The work is part of a national project funded by the Advanced Research Projects Agency for Health, known as ARPA-H, involving eight U.S. universities and three industrial partners

The project, called BRAVE for Bioaerosol Risk Assessment interVention Engineering and led by Virginia Tech, earned a contract for up to $40 million from ARPA-H’s Building Resilient Environments for Air and Total Health program. This ARPA-H “BREATHE” program focuses on sensor-based systems that monitor and respond to changes in indoor air quality as a way to revolutionize public health.

“Indoor air quality is an important and often overlooked public health issue,” said Jennifer L. West, dean of UVA’s School of Engineering and Applied Science. “The Biocomplexity Institute team will be able to make a real impact on people’s lives by bringing their diverse expertise in artificial intelligence and computational technologies to bear on a multifaceted problem.”

For UVA’s part in the BRAVE project, Marathe, executive director of the institute, and his team are building risk assessment and decision-making software for an intelligent indoor air system that can detect and respond to airborne threats, such as pathogens, in real time.

BRAVE’s collaborators think of it as an immune system for the building that perceives the threat and mounts appropriate defenses — such as increased ventilation, UV lights to kill mold or bacteria in the ducts, or even evacuation. 

“Our team will build artificial intelligence-assisted multi-scale models and decision-support systems that translate raw sensor data into actionable insights,” Marathe said in a Biocomplexity Institute news release.

“This means not only detecting the presence of pathogens but also understanding the risk they pose in real time, and helping buildings respond intelligently to keep occupants healthy.”

UVA researchers, drawing on the institute’s core expertise and working with Signature Science LLC and the University of Michigan, will combine epidemiological modeling, AI and real-time data streams to create a system that can anticipate and mitigate outbreaks before they spread.

Virginia Tech’s team, under the direction of University Distinguished Professor Linsey Marr in the Department of Civil and Environmental Engineering, will oversee the BRAVE project, including three subsets grouped by technical area: 1) Biosensors, led by Washington University in St. Louis; 2) fast modeling modules, led by UVA; and 3) engineering interventions, led by the University of California, Davis.

The BRAVE system will be piloted in childcare centers, settings that are often hotspots for respiratory infections. The UVA-developed software and decision-support system will help determine when and how to activate interventions, balancing health outcomes with energy efficiency and cost-effectiveness.


SwRI expands capabilities in large-scale heat exchanger testing



Large-Scale Heat Exchanger Test Facility can test thermal performance of heat exchangers and cooling equipment at heat loads up to five megawatts




Southwest Research Institute

Heat Exchanger 

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Southwest Research Institute (SwRI) has significantly expanded its heat exchanger evaluation capabilities. The Large-Scale Heat Exchanger Test Facility (LS-HXTF) supports testing up to five megawatts of heat loads, something few organizations offer, as well as a wider range of testing.

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Credit: Southwest Research Institute





SAN ANTONIO — November 17, 2025 — Southwest Research Institute (SwRI) has significantly expanded its heat exchanger performance evaluation capabilities with a new facility designed to industry standards, the Large-Scale Heat Exchanger Test Facility (LS-HXTF) that supports testing up to five megawatts of heat loads as well as a wider range of thermal performance testing.

Heat exchangers efficiently transfer heat between two or more fluids without mixing for a wide variety of heating and cooling applications. The market is growing rapidly and is expected to reach more than $30 billion in the next 10 years, largely driven by the data center cooling industry. As artificial intelligence applications become more widely used, data centers become more vital, as does the technology needed to cool them efficiently.

“SwRI offers customized heat exchanger testing to clients, with a wide range of unique and complex testing requirements with applications spanning several industries such as data center cooling, energy and defense to name a few,” said SwRI Research Engineer Dr. Ashok Thyagarajan. “We’ve now increased our testing capacity at the new facility tenfold to five megawatts with a vision to upgrade capabilities further in the immediate future. Additionally, we have expanded the scope of testing beyond just heat exchangers.”

SwRI now also performs testing and validation of coolant distribution units (CDUs), crucial components that distribute cooling fluid to information technology equipment, as well as other critical components, such as secondary side pumps, which pump the cooling fluid to the racks. Additionally, the LS-HXTF can now replicate real-world conditions, including loss of utility cooling with advanced control systems.

The new facility can be reconfigured and customized to accommodate equipment testing energy storage systems, power plants, or defense-related systems. This adaptability makes the LS-HXTF a critical asset not only for data centers but for broader thermal engineering research as well.

“Testing at this scale is challenging because it requires specific expertise to simulate and measure thermal behavior accurately at megawatt scales. Few laboratories can configure and adapt equipment to test both individual components and system-level solutions,” said SwRI Research Engineer Dr. Eugene Hoffman.

The LS-HXTF one of only a handful of facilities worldwide that can combine infrastructure, expertise and cutting-edge technology to provide unique insights for thermal performance testing for the data center cooling and related industries.”

For more information, visit https://www.swri.org/markets/energy-environment/fluids-engineering/data-center-cooling-testing-research.


 

Clinical trial participants call for more inclusive, patient-centered cancer research



“By embracing transparency, inclusivity, and patient advocacy, we can transform clinical trials into a true partnership between medical research and the individuals it seeks to serve.”



Impact Journals LLC

A personal perspective of patient-centred clinical trials 

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Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer review, eliminate borders between specialties by linking different fields of oncology, cancer research, and biomedical sciences, and foster application of basic and clinical science.

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Credit: Copyright © 2025 Rapamycin Press LLC dba Impact Journals Oncotarget ® is a registered trademark of Rapamycin Press LLC Impact Journals ® is a registered trademark of Rapamycin Press LLC RAPAMYCIN PRESS ® is a registered trademark of Rapamycin Press LLC





BUFFALO, NY – November 17, 2025 – A new research perspective was published in Oncotarget (Volume 16) on November 14, 2025, titled “A personal perspective of patient-centred clinical trials.”

In this perspective, led by corresponding author Jia Liu of The Kinghorn Cancer Centre, St Vincent’s Hospital, the University of New South Wales, and the Garvan Institute of Medical Research, three early-phase clinical trial participants — Trevor Tyne, Elizabeth Ivimey, and Leanne Duggan — reflect on their personal experiences with experimental cancer treatments. Their stories offer a unique perspective on the patient journey through early-phase trials and emphasize the need to design clinical research that prioritizes patients’ needs, dignity, and lived realities. The authors highlight both the life-changing opportunities that trials can provide and the systemic barriers that still prevent many patients from participating.

This perspective captures a turning point in how early-phase trials are viewed. Once considered a last resort, these trials are now increasingly offered earlier in treatment, especially with the rise of biomarker-guided therapies. In this context, the patient experience has become critical. The authors outline key benefits of participation, including access to novel therapies, ongoing medical monitoring, emotional support, and a strong sense of purpose in contributing to future medical advancements. However, they also point out significant challenges, such as restrictive eligibility criteria, high financial and logistical burdens, and communication gaps between patients and trial staff.

“While no trial guarantees success, the level of support, access to innovative therapies, and sense of contribution to medical progress can be profoundly meaningful.” 

Each narrative provides insight into the clinical trial experience. One patient explains how living with a visual impairment required tailored accessibility support throughout the trial process Another shares how genomic testing led to targeted treatment after standard options failed. Despite their different diagnoses and circumstances, all three stories reflect resilience, hope, and a shared call for trial designs that better reflect the realities of diverse patients.

To address these issues, the authors propose a number of improvements to trial design and delivery. These include expanding eligibility criteria, offering financial and logistical assistance, improving communication training for research staff, and introducing dedicated trial navigators to help guide patients through complex processes. They also focus on the importance of involving patient advocates in trial design and ensuring smoother transitions for patients moving between treatment centers.

While early-phase trials focus on safety and effectiveness, the authors argue they must also be guided by core values like ethics and patient empowerment. This perspective serves as a reminder that the future of cancer research depends not only on scientific innovation, but on an honest partnership between patients and the research community.

By sharing these real-world experiences, the article encourages a broader conversation about how to make clinical trials more responsive to the people they are designed to serve.

DOI: https://doi.org/10.18632/oncotarget.28776

Correspondence to: Jia Liu – jia.liu@svha.org.au

Abstract video: https://www.youtube.com/watch?v=2CCGN78n8ug

Keywords: cancer, precision oncology, patient-centric care, clinical trials, tumor agnostic, drug development

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About Oncotarget:

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Oncotarget is indexed and archived by PubMed/Medline, PubMed Central, Scopus, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science).

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