Saturday, October 17, 2026

 

Why Japan chose to promote AI rather than regulate it — and where that strategy hits its limits





KeAi Communications Co., Ltd.






When governments around the world set out to govern artificial intelligence, most of them reach for rules. The European Union has adopted a binding, risk-tiered framework; China steers deployment through centralised directives; and the United States relies on executive orders and agency guidance that shift with each administration. In contrast, Japan took a different route. In May 2025, its National Diet passed the Act on Promotion of Research and Development, and Utilization of AI-related Technology — a law whose organising concept is not regulation or oversight, but promotion.

In a review published in the KeAi journal Risk Sciences, two researchers from Tsinghua University and The University of Tokyo asked why Japan made this choice, and what it has achieved so far.

“The instruments a government chooses reveal its assumptions about the nature of the problem,” explains co-author Hiromi M. Yokoyama from The University of Tokyo's Kavli Institute for the Physics and Mathematics of the Universe. “The urgency of Japan's governance problem comes not from the risks of AI being used, but from the economic and social cost of AI going unused.”

The researchers described a society in which AI adoption lagged well behind other advanced economies, public trust in AI was notably low, and an ageing population coincided with ageing industrial IT systems whose maintenance engineers were approaching retirement. Labour shortages run across agriculture, nursing, construction, retail and logistics. Against this background, AI is cast as a technology that can compensate for labour the demographic structure no longer supplies.

One finding stood out. Cross-national surveys by the team show that Japanese respondents score among the highest on objective tests of AI knowledge, yet rank lowest in confidence about their own understanding. Japanese reluctance, the authors note, concentrates in trust rather than acceptance.

The study also explains why promotion could work at all in Japan. The country's tradition of administrative guidance – in which agencies steer private behaviour through non-binding recommendation – together with a corporate culture attentive to compliance and reputation, and close coordination between ministries and organised business, allows voluntary guidelines to function as real constraints without legal compulsion. The Act's central organisational instrument, an AI Strategy Headquarters chaired by the Prime Minister, is designed to overcome the fragmentation of authority across ministries that has hampered Japanese policy in other fields.

As to whether it has worked, in the period since the Act was passed, personal use of generative AI rose sharply and trial use within firms approached international levels. However, the authors identified a second dimension that promotional instruments do not reach. That is, the gap between large firms and small and medium enterprises in actual deployment has not narrowed, and self-assessed transformation maturity remains near the bottom of the scale.

"Adoption is not a single quantity," says co-author Shuo Wang of Tsinghua University's School of Marxism. "Trial and organisational integration respond to different instruments. Promotional instruments lower the cost of trying. They do not supply the capital, technical personnel or managerial authority that system replacement and process redesign require — and these are precisely what smaller firms lack."

The Japanese government appears to have reached a similar conclusion: its second AI Basic Plan, adopted in July 2026, shifts the objective to organisational change in how decisions are made and work is organised. The authors also cautioned that voluntary compliance offers weak protection against rare, high-impact events, and that codifying a promotional orientation in statute may create path dependencies that resist regulatory instruments when circumstances warrant them. Yet the annual revision built into the Basic Plan mechanism — which held through a change of premiership — offers a channel for adjustment that does not require reopening the law.

“A governance model may succeed on its own terms while the underlying problem persists in a form its instruments cannot readily reach.” Yokoyama adds. “Japan's case shows that where adoption is low, the governance problem has a different structure from the innovation-versus-risk balance that dominates comparative debate, and it calls for different instruments.”

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Contact the author: Hiromi M. Yokoyama, Center for Data-Driven Discovery (CD3), Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU, WPI), The University of Tokyo, Kashiwa, Japan. hiromi.yokoyama@ipmu.jp

The publisher KeAi was established by Elsevier and China Science Publishing & Media Ltd to unfold quality research globally. In 2013, our focus shifted to open access publishing. We now proudly publish more than 300 world-class, open access, English language journals, spanning all scientific disciplines. Many of these are titles we publish in partnership with prestigious societies and academic institutions, such as the National Natural Science Foundation of China (NSFC).

 

Owners who spend more time close to their cats tend to have more positive moods



Oxytocin levels in both pets and owners correlate




Kyoto University

Cat

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Cats joined our study with the BLE beacon.

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Credit: KyotoU / Saho Takagi





Kyoto, Japan -- Many owners will enthusiastically attest that their cat has improved their quality of life. Some studies support this common claim that caring for a feline friend has positive effects on human health and wellbeing. However, the evidence is inconsistent, and other studies have even reported possible negative effects of cat ownership.

This led a team of researchers at Kyoto University to question the idea that simply owning a cat provides intrinsic health benefits. Instead, they wondered whether any benefits or drawbacks to keeping a cat come from the quality of the relationship between the human and cat, particularly how owners interact with their cats in everyday life.

To investigate, the team conducted a one-month study of the daily lives of a group of 29 cats and their 19 owners, recruited through flyers and social media. In each household, the researchers conducted hormonal analysis through urine samples, attached Small Bluetooth Low Energy -- BLE -- beacons to the cats' collars to measure daily physical proximity, assessed the owners' mood through questionnaires, and observed the cats' behavior toward their owners and unfamiliar people.

The results revealed a hormonal connection between cats and their owners involving oxytocin and cortisol, hormones that are associated with social relationships and stress, respectively. The team observed a positive correlation in the urinary concentrations of oxytocin of both cats and owners, with higher oxytocin levels in cats linked to lower cortisol levels and fewer negative feelings in their owners. In fact, the cats' oxytocin levels were more closely associated with their owners' negative mood states than the owners' own oxytocin levels were.

Ultimately, the researchers observed that positive mood states in owners were not connected to how long they have had their cats, but rather to the overall physical proximity between owners and their cats. In other words, owners' positive feelings seem to be most strongly associated with how much time they spend close to their cats in everyday life.

"I think many cat owners are familiar with the sense of comfort and peace they feel when their cat climbs onto their lap seeking affection, they start to pet it, and the cat begins purring contentedly," says corresponding author Saho Takagi. "Our findings suggest that this feeling may be partly reflected in the hormonal connection between cats and their owners, particularly through oxytocin, a hormone involved in the formation of parent-child bonds and social relationships."

This study helps to explain why previous inquiries into the health benefits of cat ownership have produced inconsistent results by demonstrating that the quality of the relationship between human and cat matters more than simply owning a cat. However, these findings only exhibit associations, so any causation is still unclear. In the future, the team hopes to explore more deeply how cats and humans influence each other through their everyday interactions.

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The paper "Cats and humans show correlated affiliative physiological states" appeared on 13 October 2026 in iScience, with doi: 10.1016/j.isci.2026.117934

About Kyoto University

Kyoto University is one of Japan and Asia's premier research institutions, founded in 1897 and responsible for producing numerous Nobel laureates and winners of other prestigious international prizes. A broad curriculum across the arts and sciences at undergraduate and graduate levels complements several research centers, facilities, and offices around Japan and the world. For more information, please see: http://www.kyoto-u.ac.jp/en

 

Dogs can read where a person is headed from just a dozen moving dots





KeAi Communications Co., Ltd.

Experimental setup and stimulus examples. Dogs viewed point-light displays of human and dog walkers, and videos of a human turning the head.

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Experimental setup and stimulus examples. Dogs viewed point-light displays of human and dog walkers, and videos of a human turning the head.

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Credit: Xiaohan Ma et al.





A person is nothing but 13 white dots walking on a dark screen — and most of us would still recognize a human figure and probably look the way it is going. A new study published in Cognitive Science Research shows dogs can do the same, but only when the dots represent a human, not another dog.

In the study, scientists from the Chinese Academy of Sciences tested 28 working dogs with point-light displays of a person or a dog walking left, right, or forward, along with videos of a real person turning their head. The dogs were free to look wherever they liked while their reactions were video-recorded for later analysis.

When the dots depicted a human walking sideways, the dogs shifted their gaze in the same direction far more often than in the opposite direction. When the dots depicted another dog, however, the animals showed no such bias. And when the human figure walked straight toward the camera, the dogs simply kept watching the center — showing that the response reflected sensitivity to walking direction rather than movement alone.

“Dogs don't need explicit training to pick up directional social cues from human movement,” says senior and corresponding author Yi Jiang, a professor at the Institute of Psychology, Chinese Academy of Sciences, and the study’s corresponding author. “That this response is selective: it appears for human walkers but not for dog walkers, even though both displays depicted biological motion.”

The dogs’ reaction to human point-light walkers was comparable to their reaction to human head turns — a well-known social cue. “In fact, for side-facing figures, the moving dots were slightly more effective than a head turn at drawing the dogs' gaze,” adds Jiang. “These findings suggest that dogs may use a common social-attention mechanism for different human directional social signals.”

The findings add to a growing picture of how domestication may have shaped dogs' social perception. “Although many species can perceive biological motion, evidence that animals can extract directional social cues from it remains scarce,” says co-author Xiqian Lu, who is also from the same institute. “To date, such evidence has come from monkeys and rats, which acquired this ability only after extensive training. Dogs, by contrast, responded spontaneously, and only to humans.”

The researchers noted that the dogs in the study were working dogs with daily human contact, so experience may also have contributed to their responses. “As to how much of this tuning reflects domestication and how much is shaped by individual experience is the next question,” adds Lu. “For now, nonetheless, the message is clear: a handful of moving dots is enough for dogs to tell where a person is going.”

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Contact author details: Yi Jiang, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China. Email: yijiang@psych.ac.cn

The publisher KeAi was established by Elsevier and China Science Publishing & Media Ltd to unfold quality research globally. In 2013, our focus shifted to open access publishing. We now proudly publish more than 300 world-class, open access, English language journals, spanning all scientific disciplines. Many of these are titles we publish in partnership with prestigious societies and academic institutions, such as the National Natural Science Foundation of China (NSFC).

 

mRNA vaccines compared head-to-head in world-first study




Olivia Newton-John Cancer Research Institute
Research team

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L-R: Prof Stephen Kent, Dr Yi (David) Ju, Dr Shiyao Li

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Credit: Olivia Newton-John Cancer Research Institute






GLOBAL: A world-first study by Australian researchers compared three mRNA-LNP vaccine platforms in human blood samples, generating findings that could revolutionise cancer treatment and vaccine design.

mRNA-lipid nanoparticles (LNPs) transformed the way that vaccines are delivered to humans when they became widely used during the COVID-19 pandemic.

mRNA-LNPs are tiny parcels, ~800 times smaller than the width of a human hair, made of fatty acids (lipids) and containing cargo (messenger RNA) that needs to be delivered inside the body to generate a treatment response (for example, immunity to a virus).

Today, researchers around the world are investigating mRNA-LNPs as candidates for “cancer vaccines” that would deliver mRNA cargo to boost the patient’s immune system and empower it to kill cancer more effectively.

Led by researchers at the Olivia Newton-John Cancer Research Institute (ONJCRI) and the Peter Doherty Institute for Infection and Immunity, this study analysed 327 blood samples from 73 participants who received Moderna, Pfizer, or an investigational COVID-19 mRNA vaccine.

The team assessed whether the mRNA cargo was present in the blood and remained intact after delivery, the stability of the lipid-based packaging and where degradation occurred in the mRNA cargo.

Dr Yi (David) Ju, senior author of the paper published in ACS Nano and laboratory head at ONJCRI, affiliated with La Trobe University as the School of Cancer Medicine, said:

“mRNA vaccines do not all behave the same way in the bloodstream. We found differences in how quickly their mRNA and lipid components declined, and how long sections of the mRNA remained intact.”

The researchers also found that much of the circulating mRNA measured in the Moderna and Pfizer groups was fragmented. A more detailed analysis in six Moderna recipients found that the mRNA was less intact near one end of the mRNA molecule, a pattern also seen in the original vaccine formulation.
The findings provide strong clues on how to make the vaccines more stable, likely making them much more efficient so that patients can receive lower vaccine doses that cause fewer side effects.

Prof Stephen Kent, first author of the study and laboratory head at the Doherty Institute, said:

“These findings give us a way to compare the mRNA cargo and lipid delivery components of different vaccines in people. That knowledge will help us design and evaluate future improved, more efficient mRNA vaccines and therapeutics, including approaches being developed for cancer.”

By establishing a framework to compare mRNA-LNP platforms in humans, the study can help guide the development of more effective mRNA-based medicines.

ENDS 

Publication available at: https://doi.org/10.1021/acsnano.6c09226

   

About the Olivia Newton-John Cancer Research Institute (ONJCRI)  

ONJCRI is a global leader in advancing cancer research, driven by the singular goal of improving patient outcomes. We drive progress by discovering and developing diagnostics and therapeutics that are more effective, tolerable, and accessible. ONJCRI adopts a tumour-agnostic approach, targeting shared pathways across multiple cancer types. This innovative strategy enables us to deliver scalable and impactful therapies that benefit diverse patient populations, accelerating progress across the entire landscape.  

By bridging laboratory discoveries and clinical applications, ONJCRI is redefining how cancer treatments are designed and delivered: from bedside to bench to bedside. With a steadfast commitment to equity, innovation, and collaboration, we strive to transform cancer care, addressing unmet needs and overcoming disparities in access for all communities. For more about the Olivia Newton-John Cancer Research Institute, visit www.onjcri.org.au.  

ONJCRI is an independent medical research institute and is affiliated with La Trobe University as the School of Cancer Medicine.  

 

Harvard announces new licensing model to help startups launch faster



ExpressPath initiative streamlines process from lab discovery to commercialization




Harvard Office of Technology Development

Harvard engineering building

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Harvard Science and Engineering Complex

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Credit: Grace DuVal/Harvard University






ExpressPath, a new licensing model for Harvard engineering, medical device, and software technologies, is helping academic innovators turn promising ideas into real-world products faster and more efficiently.

Harvard launched ExpressPath to minimize the friction in the licensing process across three technology pathways: Engineering & Technology, Medical Device, and Software. The initiative offers market-rate financial terms benchmarked against a wide range of peer universities, along with a simplified license agreement. Researchers can review the terms and license agreement on the Harvard Office of Technology Development (OTD) website, giving startup teams and investors greater transparency and predictability from the outset. 

The initiative is part of a larger strategy to streamline the process from lab discovery to commercial products and services. In the coming months, OTD will also launch initiatives designed to make it easier and clearer for industry to fund research in Harvard labs. 

“The ExpressPath model is one part of Harvard’s broader effort to make it easier for research discoveries to move beyond the laboratory and into the world,” said Harvard’s Senior Vice Provost for Research John Shaw. “By reducing uncertainty and creating a clear path to commercialization, we can help researchers, founders, and investors move promising innovations forward more effectively and at a faster pace.”

To get started, researchers can review the three ExpressPath licensing tracks, including eligibility and license terms, on the OTD website. Teams interested in pursuing an ExpressPath license work with the OTD team to determine which pathway is the best fit. Once eligibility and fit are confirmed, OTD and the team can move quickly to execute an ExpressPath license, eliminating the typical negotiation phase that can delay the commercialization journey. 

“We want the licensing process to move faster so startup teams can focus on the hard work of commercializing early-stage technology and building a company,” says Sam Liss, OTD’s chief technology development officer and associate provost. “Based on my discussions with faculty, researchers, and investors, it’s clear that the ExpressPath model will greatly simplify and streamline licensing.”

The ExpressPath program includes specific pathways for three technology areas:

  • Engineering and technology, which includes instruments, quantum technologies, advanced materials, coatings, hardware, electronics, AI algorithms, robotics, energy, environmental technologies, and other physical science innovations;
  • Software, which offers two tracks depending on the needs of the startup team; and
  • Medical devices, which includes devices used in healthcare — excluding traditional therapeutics and biologics.

To develop the program, OTD reviewed hundreds of technology licenses at other universities across the U.S. OTD also consulted with a variety of external stakeholders including MassVentures, a venture capital firm and economic development agency for the Commonwealth of Massachusetts that funds early-stage technology startups, as well as other investors and entrepreneurs to ensure the terms met fair market benchmarks.

Offering pre-defined, benchmarked financial terms and a simplified licensing agreement at the start of the process can shrink negotiations that can take more than six months and involve tens of thousands of dollars in legal fees, into a matter of weeks, if not less time. “Simply put, ExpressPath removes the haggling,” says Liss. “It's really a different paradigm for how licensing will be done at Harvard for eligible startups.” The process will also be much more consistent for entrepreneurs and investors, as the terms will be pre-set for eligible companies, rather than negotiated on a case-by-case basis.

Licensing processes represent a “big bottleneck” for funders and entrepreneurs, says Russ Wilcox, an investor and entrepreneur who has gone through the process about half a dozen times. It can create a chicken-and-egg problem for would-be companies — funders generally want proof of license before investing in a startup, while a startup needs funds to undertake the licensing process.

“I think ExpressPath will have benefits for everybody" who needs to pursue licensing, Wilcox says, saving both time and money, and providing investor confidence in the licensing process. He expects the program’s ease could allow more startups to grow from university labs because VCs will see fewer potential barriers to licensing intellectual property from them. 

“Anything that makes it more likely that a great company can get going faster, using less capital to get started, is a good thing for innovation,” says Katie Rae, CEO and Managing Partner at Engine Ventures, who has served on several OTD entrepreneurship committees.

After licensing, “the real work” begins, according to Rae: “Then you have to go make a company out of it.” By lowering the barriers that come before, she says, “Harvard is listening and investing in the translation phase of innovation — it is fundamental to the economy.”

Learn more: https://otd.harvard.edu/researchers/licensing-startup-formation/harvard-expresspath-licenses/

 

Using AI to boost advanced reactor safety



Brown contributes to DOE Genesis Mission



University of Tennessee at Knoxville

Using AI to Boost Advanced Reactor Safety

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University of Tennessee, Knoxville Department of Nuclear Engineering (NE) Professor Nick Brown.

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Credit: University of Tennessee






This summer, the United States Department of Energy (DOE) announced the new Genesis Mission—a $5 billion program to create a nationwide ecosystem of AI tools and services that will help American researchers address pressing energy, scientific, and engineering challenges. The DOE awarded Phase I support to 277 projects across the nation, giving them a chance to apply for Phase II funding if they achieve promising results over the next nine months.

Just one project was granted immediate Phase II funding: Prometheus, an AI platform designed to cut nuclear reactor deployment timelines and operating costs in half.

“Nuclear energy is one of our most important sources of baseload electricity, providing 20% of our power (nationally),” said University of Tennessee, Knoxville Department of Nuclear Engineering (NE) Professor Nick Brown, a co-PI on the project. “However, deployment of new reactors has slowed significantly since the 1970s, while many existing reactors are approaching retirement.”

Spearheaded by Idaho National Laboratory (INL), Prometheus unites DOE national laboratories, universities, and commercial partners to develop AI tools that will accelerate the deployment of reactors and related facilities across the nuclear fuel cycle. The project has significant support from across the industry, including leading advanced reactor companies such as TerraPower, Oklo, and X-energy.

Brown is a nationally recognized expert on nuclear fuel safety and advanced reactor design with established collaborations at several national laboratories. In fact, five of Brown’s former group members are current staff researchers at INL and a sixth is expected to join soon.

NE Associate Professor Vlad Sobes and Assistant Professor Xingang Zhao are also bringing their expertise to the project, maintaining the University of Tennessee’s position as a leader in nuclear technology and development.

“The capabilities of agentic workflows have advanced incredibly over the last several years, enabling systematic increases in productivity,” Brown said. “We are excited to be on the cutting edge of the application of these workflows to advanced nuclear reactors.”

Ensuring Future Reactor Safety

Maintaining safety and regulatory compliance is a core pillar of the Prometheus mission. Brown’s group has a well-established research partnership with INL—especially in the areas of advanced reactor and nuclear fuel safety—so he was a natural choice to help lead the project.

Over the next three years, Brown, Sobes, and Zhao will develop AI-based tools to evaluate how the nuclear fuel in new advanced reactor designs will behave under transient and accident conditions.

Sobes, an expert in applying AI to problems in the nuclear data pipeline, will advise Brown’s team on the AI-related aspects of the project. Zhao, whose research focuses on developing integrated AI-based models and simulations to enhance the safety and operational performance of nuclear power plants, will collaborate with Brown on thermal hydraulics and technoeconomic analysis.

“We will be applying Prometheus workflows and developing agents that will enable rapid and comprehensive evaluations of advanced nuclear reactor design and safety,” Brown explained.

The Prometheus team plans to deploy its initial commercial-grade production platform in March 2027, with broader adoption across the industry and the DOE later that year. Overall, the platform is expected to facilitate innovation across the entire nuclear industry.